Application Notes

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What’s Happening in Chemometrics?
Wednesday, June 01, 2005
Susan Foulk
Chemometrics is the discipline associated with the application of mathematical and statistical methods to chemical measurements. Read More
$Increasing Application of X-Ray Powder Diffraction in the Pharmaceutical Industry$
Increasing Application of X-Ray Powder Diffraction in the Pharmaceutical Industry
Wednesday, June 01, 2005
Brian Litteer Detlef Beckers
X-ray powder diffraction has recently been propelled to the forefront as an analytical tool in the pharmaceutical industry for a wide range of applications. Read More
Coupling Fourier Transform Infrared Spectroscopy to Gel Permeation Chromatography via a Liquid Flow Cell
Friday, July 01, 2005
Greg D. Saunders Steve J. O’Donohue Paul J. DesLauriers
Fourier transform infrared (FTIR) spectroscopy is a well-established technique used in the compositional analysis of materials through the measurement of vibrational absorption bands. Read More
Quartz Crystal Microbalance/Heat Conduction Calorimetry
Friday, July 01, 2005
Allan L. Smith
One need only look around to see that the world is full of surfaces. Read More
A System That Helps Scientists See Drugs in Tissue Samples
Friday, July 01, 2005
Mark Springer
For drug developers, being able to see where a drug candidate is distributed in a targeted tissue helps them better assess the potential value of that compound as a pharmaceutical product. Read More
The Importance of Controlled Concentration and Drying in MALDI-TOF Applications
Friday, July 01, 2005
Steve Knight
Matrix-assisted laser desorption/ionization-time- of-flight mass spectrometry (MALDI-TOF MS) is now an accepted and routine analysis technique for the elucidation and quantitation of biomolecules ... Read More
Continuous Gas Supply for the Cryo/Bio Laboratory: Increased Performance, Safety, and Cost Efficiency
Monday, August 01, 2005
Patrick Carlucci David Durkin
Traditionally, the de rigueur source of gas supply for most laboratory and process equipment has been the high-pressure gas cylinder. Read More
A High-Sensitivity Sensor for DSC
Friday, August 05, 2005
Rudolf Riesen Blaine Weddle
A dramatic increase in sensitivity at low signal noise without a significant loss in signal resolution has been achieved with the HSS7 high-sensitivity sensor. Read More
Creating Rich Web-Based LIMS With Programmable XML Technologies
Thursday, September 01, 2005
Dinu Toiba
Laboratory information management systems convert mass amounts of data into analytical information useful throughout the enterprise. Read More
Image Analysis of Neurite Branching: High-Content Screening at High Speed
Thursday, September 01, 2005
Pascal Vallotton Leanne Bischof Michael Buckley Ryan Lagerstrom Changming Sun Hugues Talbot Dadong Wang
Automated image analysis is becoming a central tool for quantifying the effect of candidate drugs on cells. Read More
The Significance of pH Stability for Cell Cultures
Thursday, September 01, 2005
Daniela Maurer
Cell culture media generally comprise amino acids, salts, vitamins, other substances, and an anorganic buffer substance (NaHCO3). Read More
On-Site Wastewater Analysis Using a TOG/TPH Analyzer
Thursday, September 01, 2005
Sandra Rintoul
It is estimated that 23–28% of sanitary sewer overflows (SSOs) are due to fats, oils, and grease (FOG). Read More
Ten Steps to Maintaining Gas Stream Purity
Friday, September 23, 2005
Frank Kandl
Many problems in gas chromatography follow a cylinder change-out, prompting chemists to buy ever-higher purity grades of gas. Read More
An NPDES Distillation Method for Measuring Total Cyanide in Water
Saturday, October 01, 2005
John R. Sebroski Karin L. Bogren
Used for total cyanide distillation, the MICRO DIST system was granted National Primary Drinking Water Regulations (NPDWR) approval in 2003 and is expected to receive nationwide Tier III approval for ... Read More
Tips to Prevent Streaking on 2-D Gels
Tuesday, November 01, 2005
Tom Berkelman Mary Grace Brubacher Haiyin Chang Tim Cross William Strong
The most common problem encountered with 2-D gels is protein streaking, whether in the horizontal or vertical direction. Read More
Flow Characterization: Selecting Appropriate Technology
Tuesday, November 01, 2005
Steve Carrington Joanne Langridge
It is well known that measuring the rheological properties of materials contributes to the development of better products and helps predict end-use performance as well as the physical properties of a... Read More
Exploring the Full Range of Temperature When Faced With a Difficult Separation
Thursday, December 01, 2005
R. Travis Tucker Stephanie Marin Neal E. Craft John E Estes
Carotenoids such as beta-carotene, lutein, zeaxanthin, and lycopene are believed by many scientists to act as powerful antioxidants that protect against heart disease and cancer and boost the immune ... Read More
Making Surface Tension Measurement a Practical Utility for Modern Industrial R&D
Thursday, December 01, 2005
Christoffer Johans Ilkka Palonen Pekka Suomalainen Paavo K.J. Kinnunen
Vast numbers of new surfactants are introduced annually for improved formulation and functionality in products ranging from personal care (e.g., soaps, shampoos, sun care, and cosmetics products), ... Read More
Mercury Measurements: Overcoming Contamination and Interferences to Enable the Correct Measurements for Valued Judgments
Thursday, December 01, 2005
Peter B. Stockwell Warren T. Corns Derek W. Bryce
Interest and concern about the levels of mercury in its various forms in the environment have been well documented over the last 50 years. Read More
A Multifrequency Temperature- Modulated Technique For DSC
Sunday, January 01, 2006
Markus Schubnell Christoph Heitz Thomas Hütter Steven Sauerbrunn Juergen E.K. Schawe
In conventional differential scanning calorimetry (DSC), a sample is subjected to a temperature program with a constant heating rate. As a result, the DSC instrument delivers an output signal, which, ... Read More