Technical Articles

This real-world example of calibration diagnostics involves the ion-chromatographic behavior of phosphoric acid; phosphate is the actual analyte form that is measured by the instrument. read more

This installment will present the sixth and last in this series of calibration examples. read more

The previous several articles have dealt with calibrationstudy design and calibration-diagnostic procedures. read more

The previous two installments have discussed the issue of nonideal recovery, a problem that occurs in many analytical methods. read more

In the previous article (Part 27, American Laboratory, Sept 2007), the world of detection was shown to revolve around three variables: 1) the detection limit, 2) the probability of false positives, a,... read more

In Part 29 (American Laboratory, Feb 2008), Hubaux-Vos detection limits (H-V DLs) were explained and an illustration was given. read more

As was mentioned in the first article on detection limits (DLs) (Part 26, American Laboratory, June/July 2007), many formulas exist for calculating these values. read more

The subject of detection limits (DLs) is a controversial one, generating many questions and almost endless debate. read more

The previous article (Part 35, American Laboratory, Aug 2009) introduced the concept of significant digits, pointing out that a statistically sound treatment will: 1) result in a formula that depends ... read more

In this series of articles, all of the regression discussions to date have assumed that the replicate preparations of a given concentration have been exact. read more