Read the Latest Technical Articles for Lab Professionals - Technical Articles

Sort

Scientific Imaging: To Sharpen or Obscure?
Monday, October 01, 2012
Jerry Sedgewick
In the world of scientific imaging, the matter of whether or not to sharpen an image can pose an ethical question: Does sharpening change the essential nature of the image? read more
Science-Based Hydraulic Fracing: Review of the ACS Regional Meeting
Wednesday, February 05, 2014
Robert L. Stevenson, Ph.D.
The above headline is not a typo, since there is no “k” in “hydraulic fracturing.” This correction was just one of many misconceptions addressed in a daylong session on hydraulic stimulation of petro-... read more
Scaling the Scaffolds: Control of Pore Size in Tissue Engineering Scaffolds
Tuesday, November 01, 2011
Katriona Scoffin
A bioscaffold is a medical device designed to support the growth of new tissue. Scaffolds are used in vivo to support the regrowth of soft tissues and bone after surgery or injury; in vitro they ... read more
sbv IMPROVER: Species Translation Challenge Open to the Scientific Community for Submissions
Monday, June 10, 2013
Manuel C. Peitsch
The organizers of sbv IMPROVER (Industrial Methodology for PROcess VErification in Research) are currently accepting submissions for the Species Translation Challenge, an innovative crowd-sourcing... read more
Sample Prep for LC, GC, and SFC at Pittcon® 2013
Friday, May 10, 2013
Robert L. Stevenson, Ph.D.
At Pittcon® 2013, sample prep stood out as a major focus, perhaps because of the few advances in chromatography instrumentation. In addition, some sample preparation is spilling over into other ... read more
Routine Implementation of Very-High-Pressure Liquid Chromatography in Pharmaceutical Development
Monday, March 01, 2010
Qinggang Wang Brent Kleintop
High-pressure liquid chromatography is probably the most widely used analytical technique for characterizing drug substances and drug products in the pharmaceutical industry. It is widely employed ... read more
Robust Solutions for High-Temperature Biodiesel Analysis: Combining Deactivated Metal Columns, Leak-Tight Coupling, and Built-In Retention Gap Technology
Tuesday, January 01, 2008
Jaap de Zeeuw Barry L. Burger
There has been a huge increase in the use of biodiesel fuels. read more
Review of U.S. EPA Methods for Perchlorate Using Suppressed Conductivity Detection
Tuesday, January 22, 2013
Jeff Rohrer Richard Jack Brian De Borba Lillian Chen
Perchlorate is identified as an environmental contaminant found in drinking, ground, and surface waters. The origins of perchlorate are both natural and anthropogenic. In its natural origin, ... read more
Results are in for the Second sbv IMPROVER Challenge on Species Translation
Friday, November 08, 2013
Robert L. Stevenson, Ph.D.
Species translation involves searching for biological mechanisms of action (MoA) that are common to different species, in this case, humans and rats. In addition to the interesting scientific question... read more
Reliable Clinical and Forensic Drug Testing: Guideline Supports High-Quality Standards in Laboratory Analysis
Friday, October 24, 2008
Melissa D’Archangelo
Developing reliable and efficient procedures for clinical and forensic drug testing is a challenge for many laboratories. read more
Regulatory Considerations When Developing Assays for the Characterization and Quality Control of Antibody-Drug Conjugates
Monday, August 27, 2012
Marjorie A. Shapiro Xiao-Hong Chen
Therapeutic monoclonal antibodies can be conjugated with a variety of molecules including small-molecule drugs, radionuclides, peptides, other proteins (protein toxins, enzymes, cytokines), and ... read more
Reflections on a Third-Generation Mobile Phase Recycler for HPLC
Wednesday, February 01, 2006
Al Welch
The volume of HPLC mobile phase (MP) purchased and discarded each year is about 20,000,000 L, or enough to fill two rail trains each with 100 tank cars. On average, each of the 200,000 active HPLCs... read more
Reducing DNA Sample Backlogs and Protecting Chain-of-Custody in the Forensic Laboratory
Monday, December 24, 2012
Laurent Baron Bobby Chavli Lois Tack Annette Summers
For years, forensic laboratories in the U.S. have struggled to reduce DNA sample processing backlogs and human errors, both of which hinder timely and reliable criminal convictions. read more
Real-Time Detection of Central Nervous System Tissues on Bovine Carcasses Using Fluorescence Spectroscopy
Wednesday, September 01, 2010
Ramkrishna Adhikary Prasun Mukherjee Holger Schönenbrücher Thomas A. Casey Mark A. Rasmussen Jacob W. Petrich
Bovine spongiform encephalopathy (BSE) is a fatal, neurodegenerative transmissible spongiform encephalopathy (TSE) in cattle that is thought to be the cause of variant Creutzfeldt-Jakob disease (vCJD)... read more
Rapid, Robust, and Sensitive Detection of 11-nor-Δ⁹-Tetrahydrocannabinol-9-Carboxylic Acid in Hair
Thursday, September 01, 2011
Bernhard Rothweiler Fred Feyerherm David Engelhart Stephan Baumann
Testing hair for drugs of abuse has been practiced for over 50 years, due in large part to the ability to detect drug use over a longer period of time, as compared to other biological matrices, ... read more
Rapid, Quantitative Analysis of Multiple Mycotoxins by Liquid Chromatography Tandem Mass Spectrometry
Sunday, April 01, 2007
Mahalakshmi Rudrabhatla Jason S. Wood
The classical example of detrimental effects caused by bacteria, such as E. coli or Bacillus Anthracis, is through invasion of the host. read more
Rapid Enantiomeric Excess Determination of D- and L-Proline Using Electrospray Ionization–Mass Spectrometry
Thursday, September 01, 2011
Heidi Fleischer Kerstin Thurow
The enantiomeric composition of proline is commonly determined using conventional analytical methods such as HPLC, GC, and CE. read more
Rapid Determination of Nine Chemotherapeuticals in Animal Feed by HPLC-DAD Using a Monolithic Column
Thursday, June 01, 2006
Rita Bibi Gloria R. Tovo Ivan Pecorelli
Chemotherapeuticals as feed additives were widely used in the European Union to prevent and control many diseases in food-producing animals, read more
Rapid and Automatable Desalting of Proteins and Protein Complexes by Size Exclusion Chromatography for On-Line Detection by Native Mass Spectrometry
Friday, June 14, 2019

Online buffer exchange is an effective screening tool that bridges the gap between protein expression and time-consuming structural biology methods. read more
Raman Imaging as a Tool for Characterizing Carbon Nanomaterials
Monday, March 31, 2014
Michael Arnold Mark Wall Susmit Singha Roy Robert Jacobberger Gerald Brady
In recent years, carbon nanomaterials have created their own niche in materials science due to their exceptional electronic, thermal, mechanical, optical, and magnetic properties, creating potential ... read more

Technical Articles

Sort

Scientific Imaging: To Sharpen or Obscure?

Science-Based Hydraulic Fracing: Review of the ACS Regional Meeting

Scaling the Scaffolds: Control of Pore Size in Tissue Engineering Scaffolds

sbv IMPROVER: Species Translation Challenge Open to the Scientific Community for Submissions

Sample Prep for LC, GC, and SFC at Pittcon® 2013

Routine Implementation of Very-High-Pressure Liquid Chromatography in Pharmaceutical Development

Robust Solutions for High-Temperature Biodiesel Analysis: Combining Deactivated Metal Columns, Leak-Tight Coupling, and Built-In Retention Gap Technology

Review of U.S. EPA Methods for Perchlorate Using Suppressed Conductivity Detection

Results are in for the Second sbv IMPROVER Challenge on Species Translation

Reliable Clinical and Forensic Drug Testing: Guideline Supports High-Quality Standards in Laboratory Analysis

Regulatory Considerations When Developing Assays for the Characterization and Quality Control of Antibody-Drug Conjugates

Reflections on a Third-Generation Mobile Phase Recycler for HPLC

Reducing DNA Sample Backlogs and Protecting Chain-of-Custody in the Forensic Laboratory

Real-Time Detection of Central Nervous System Tissues on Bovine Carcasses Using Fluorescence Spectroscopy

Rapid, Robust, and Sensitive Detection of 11-nor-Δ⁹-Tetrahydrocannabinol-9-Carboxylic Acid in Hair

Rapid, Quantitative Analysis of Multiple Mycotoxins by Liquid Chromatography Tandem Mass Spectrometry

Rapid Enantiomeric Excess Determination of D- and L-Proline Using Electrospray Ionization–Mass Spectrometry

Rapid Determination of Nine Chemotherapeuticals in Animal Feed by HPLC-DAD Using a Monolithic Column

Rapid and Automatable Desalting of Proteins and Protein Complexes by Size Exclusion Chromatography for On-Line Detection by Native Mass Spectrometry

Raman Imaging as a Tool for Characterizing Carbon Nanomaterials

Product Guide

Micromachined HPLC Columns Can Revolutionize Proteomics Workflows

Buyer's Guide: GC-MS for Monitoring Environmental Pollutants

Refocusing the Lens of Cancer Screening

Study: NGS Should Be Go-to Technology on Day Zero of the Next Pandemic

Overcoming Common Challenges in Sample Viability for Single-Cell Research