Technical Articles

The previous article (American Laboratory, Apr 2011) ended with an unsolved problem: how to implement a pass-fail method if the blank matrix contains a non-negligible amount of the analyte. read more

Consider the following algebraic equation: 5x + 11y + 39z = 106 Since this single expression has three unknowns, there are many possible solutions; a single exact solution cannot be found. read more

Since the beginning of this series of articles, the central topic has been calibration and its associated uncertainty. read more

Welcome to “Statistics in analytical chemistry.” read more

Measurement is at the heart of what analytical chemists do on a routine basis. read more

This fourth real-world example of calibration diagnostics comes from the same study as did Part 13 (American Laboratory, Sept 2004). read more

This month’s installment is the second in a series of real-world examples of calibration diagnostics. read more

This month's article will conclude the three-part series explaining calibration diagnostics. read more

The past seven articles have provided the fundamentals of calibration, including a protocol for designing a calibration study. read more

In the last installment in this series, it was suggested that a rule-of-thumb for calibration designs was five-by-five (i.e., five replicates of each of five concentrations), for a total of 25 data ... read more