Application Notes

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Liquid Handling Uses Acoustic Droplet Ejection for Improved Results
Monday, May 08, 2017
Mark Fischer-Colbrie
Acoustic drop ejection systems can pave the way for entirely new applications, bringing higher throughput and greater flexibility to many areas of biology. Read More
Using Advanced Data-Management Solutions to Ensure Food Safety
Monday, May 08, 2017
Jeff Tishler Kevin Arnold
Accurate recording of research data and the ability to quickly search historical data and track the genealogy of products result in products being developed more rapidly and consistently while ... Read More
Quantitating VOCs in Serum Using Automated Headspace-SPME/Cryo-Focusing/Isotope Dilution/Capillary GC/MS
Friday, March 31, 2017
Paul R. Loconto
In January 2007, the author’s lab received a frozen shipment of calibration standards and quality control (QC) samples to perform method validation for quantitating traces of volatile organic ... Read More
Advances in Single-Cell Biology Using Mass Spectrometry
Wednesday, March 22, 2017
Rohan Thakur
Single-cell analysis by MS has proven extremely valuable in discovering unique neuropeptides in a broad range of animal models, from complex mammalian species to simpler organisms such as sea slugs. Read More
Automated Liquid Handling Facilitates Immunofluorescence Assay Optimization
Tuesday, March 21, 2017
Wendy Goodrich
This article describes the high-resolution capability of an automated imager equipped with oil immersion microscope objectives. Read More
GC×GC-MSq: A New Tool in Arson Investigation
Tuesday, March 21, 2017
Clifford M. Taylor A. Kirk Rosenhan Joey M. Raines Jose M. Rodriguez
Two-dimensional gas chromatography-quadrupole mass spectrometry (GC×GC-MSq) is a powerful tool for complex arson analysis. Read More
Identifying Whiskey Adulteration by GC/MS Through Chemical Profiling and Differential Analysis
Tuesday, March 21, 2017
Paul Silcock Dominic Roberts Jana Hajslova Jana Pulkrabova
GC/MS used with statistical analysis and structural elucidation software rapidly determines the complex chemical composition of whiskies. Read More
Individual Cell Analysis for Protein Expression and Cell Health Markers
Tuesday, March 21, 2017
Robin T. Clark
The Muse instrument uses microcapillary fluidics and preoptimized reagents to create an inexpensive, compact, portable cell analyzer that requires minimal setup and no expertise to operate. Read More
Design and Use of Multiplex Immunoassays Based on Oligonucleotide Tethering
Tuesday, March 21, 2017
Robert S. Matson
Oligonucleotide tethering offers an unconventional approach to antibody immobilization. Read More
Lab Vacuum Pumps: Selection and Protection
Friday, February 17, 2017
Peter Coffey
Useful tips are given for choosing the right vacuum pump for the lab. Read More
Comparison of ICP-QQQ and MP-AES to Alternative Atomic Spectroscopy Techniques
Friday, February 17, 2017
Shane Elliott
This article gives an overview of the various atomic spectroscopy techniques available to address a range of applications in environmental science, food and agriculture, life sciences and academic ... Read More
Refrigeration Practices for Biological Sample Preservation
Friday, February 17, 2017
Robert Sandor
Preservation of biological samples such as tissues, plasma and forensic and pathology specimens relies on maintaining proper storage temperatures and on the type of sample and analysis to be done. ... Read More
Improved Method to Quantitate Gluten in Purified Wheat Starch
Friday, February 17, 2017
Katharina Anne Scherf Peter Koehler
A new HPLC method may be applied as a confirmatory method to ELISA, particularly to check for the presence of glutenins in WSt rendered gluten-free. Read More
Super-Resolution Microscopy Techniques Combine to Clarify Spatiotemporal Structure of the Endoplasmic Reticulum
Friday, February 17, 2017
Robert L. Stevenson, Ph.D.
Super-resolution microscopy encompasses several new techniques for direct spatiotemporal imaging of structural features much smaller than the diffraction limit of light. The endoplasmic reticulum (ER)... Read More
Comparison of Crystallization Behavior of Different-Colored Polypropylene Parts Using a Single DSC Experiment
Friday, January 20, 2017
James A. Browne
A compositional analysis may explain the reasons for variations in processing behavior, but is time consuming and expensive. As an alternative, straightforward differential scanning calorimetry (DSC) ... Read More
A High-Throughput Method for Routine Analysis of Pesticide Residues on Cannabis
Friday, January 20, 2017
David Egerton
Testing for pesticide residues in Cannabis must be sensitive, selective, fast and affordable. The method described in this article uses HPLC with triple-quadrupole mass spectrometry. Read More
Proper Monitoring of Refrigerators and Freezers to Protect Valuable Biomedical Inventory
Friday, January 20, 2017
Rob Fusco
Best practices for cold storage must be followed to protect valuable samples. Important goals are to avoid degradation, which stems from high and low temperature extremes, and prevent loss of potency ... Read More
High-Throughput VOC and Inorganic Gas Analysis: Automated SIFT-MS
Friday, January 20, 2017
Mark J. Perkins Vaughan S. Langford Murray J. McEwan
A sensitive technique called selected ion flow tube mass spectrometry (SIFT-MS) allows the direct, real-time monitoring of inorganic gases and volatile organic compounds (VOCs), with no need to ... Read More
siRNA Knockdown: Implementing Negative Controls in Antibody QC
Friday, January 20, 2017
Will Olds
This article presents an overview of short interfering RNA (siRNA) knockdown, a powerful negative control method, followed by tips to optimize siRNA transfection experiments. Read More
Bringing Raman Spectroscopy to the Undergraduate Laboratory
Friday, January 20, 2017
Brian Marquardt Giora Proskurowski
Designed specifically for the educational environment, a Raman tool incorporates a safe way to operate laser in a durable, open package, offered at about a third of the price of a traditional Raman ... Read More