Application Notes

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Time-Efficient Execution of Rheological Tests in Oscillation With an Easy-to-Use Quality Control Rheometer
Friday, August 07, 2015
Fabian Meyer
Quality control managers are under constant pressure to conduct analyses as efficiently and cost-effectively as possible. In certain industries, such as paints and coatings and food, rheological ... Read More
Glycoxidative Modification of Adenosine in Relation to Diabetes and Obesity: Detection of Carboxymethyl-Adenosine in Biological Samples
Friday, August 07, 2015
Zeenat Ara Lila Louis D. Whitesides Chukudi Weze Yazmine Thomas
Proteins are modified in residues of lysine, arginine, histidine, etc., due to high concentrations of sugar and fatty acids in the bloodstream in relation to diabetes. Read More
Electronic DNA Sample Processing Preserves Evidence Integrity in the Forensics Laboratory
Tuesday, August 11, 2015
Joanie Brocato
Ten years ago, most forensics laboratories tested and analyzed a manageable number of samples. Read More
A DNA-Based Screening Assay to Streamline Sexual Assault Sample Processing
Tuesday, August 11, 2015
Allison Holt Michele Marfori Denise Yong Ning Oh Sheri Olson
Sexual assault kit (SAK) samples account for a significant portion of backlogged cases in forensic laboratories. Read More
Use of Weighted Least Squares and Confidence Band Calibration Statistics to Find Reliable Instrument Detection Limits for Trace Organic Chemical Analysis
Friday, September 11, 2015
Paul R. Loconto
Instrument detection limits (IDLs or xD) obtained from applying either ordinary least squares/confidence band calibration statistics (OLS/CBCS) or weighted least squares/confidence band calibration ... Read More
Simple Cell Imaging for Complex Research
Monday, September 21, 2015
Veronika Kortisova Descamps
The average rat brain is about the size of a pea and is divided into more than a dozen functional structures. Read More
Microbiological Testing Using Nutrient Pad Sets for Quality Assurance of Beverages
Wednesday, September 23, 2015
Juliane Pfützenreuter
Inspection of final product is no longer sufficient to meet beverage quality assurance requirements. Read More
Statistics in the Laboratory: A New American Laboratory Column
Friday, September 25, 2015
Stanley N. Deming
Welcome to “Statistics in the Laboratory.” This column will appear four times a year and will build on the popular “Statistics in Analytical Chemistry” series by David Coleman and Lynn Vanatta ... Read More
Five Ways to Improve the Workflow and Financial Health of the Laboratory
Friday, September 25, 2015
Trish Meek
Henry Ford quipped, “There are no big problems; there are just a lot of little problems.” Read More
Quantitative Analysis of H2A.X and ATM DNA Damage Signals Using Benchtop Flow Cytometry
Friday, September 25, 2015
Mark Santos Wenying Zhang
Assessing the level of DNA damage present in cells is integral to understanding the molecular mechanisms involved in the genome repair process and consequences for cell fate. Read More
Examining the Multiple Parameters of Glycolytic Activity
Monday, September 28, 2015
Maya Dubey
Cellular energy enables vital activities such as proliferation, differentiation, stimuli response and intracellular signaling. Read More
Recent Advances in ICP Spectrometers
Monday, September 28, 2015
Mark Grey
When SPECTRO Analytical Instruments (Kleve, Germany) sought to redesign its inductively coupled plasma (ICP) spectrometer instrument line, the company’s engineers worked to address some very specific ... Read More
In-House Pipette Calibration: The Lean Way
Thursday, October 08, 2015
A. Björn Carle
Sorenson Genomics of Salt Lake City focuses on DNA testing, with its expertise in quality, high-throughput testing that spans several diverse business units and highly accredited laboratories. Read More
Innovative Sample Prep Removes Lipids Without Losing Analytes
Thursday, November 19, 2015
April DeAtley Limian Zhao Derick Lucas
Interference from lipids is a common problem for laboratories measuring trace residues in fatty foods or complex biological matrices: their presence in a sample can cause significant matrix ... Read More
The Road to Improved Next-Generation Sequencing Through Innovative PCR Instrumentation
Friday, November 20, 2015
Andrew Birnie
Next-generation sequencing (NGS), one of the most significant technological advances in the the last 30 years, allows millions of DNA strands to be sequenced in parallel. Read More
Getting the Most Out of Limited Samples: A PCR Workflow for Monitoring Gene Expression
Tuesday, November 24, 2015
Joshua Fenrich
Seeking to identify the biochemical triggers that commit stem cells to distinct fates, researchers at the Lunenfeld-Tanenbaum Research Institute at Mount Sinai Hospital in Toronto assessed the culture... Read More
Maple Syrup Color Analysis Using UV/VIS Spectrophotometry
Tuesday, November 24, 2015
Jeff Head John Kinyunjui Mark Talbott Robert Clifford
UV/VIS spectrophotometry is a valuable tool for measuring the properties of liquids and solids. Read More
Optical Tweezers for Single-Cell, Multicellular Investigations in the Life Sciences
Thursday, November 26, 2015
Torsten Jähnke Philipp Rauch
With accuracy down to single piconewtons, optical traps measure forces exerted on microscopic objects without mechanically touching them. Read More
A Clearer View of 3-D Cell Culture: Optimizing Fluorescence Imaging and Analysis
Tuesday, December 01, 2015
Cecile Villemant Grant Cameron Jenny Schroeder
The study of cells in two-dimensional (2-D) culture systems, usually in a well plate or in a flask, has contributed to the understanding of many biological processes. Read More
Statistics in the Laboratory: Control Charts, Part 1
Tuesday, January 26, 2016
Stanley N. Deming
Statistical process control (SPC) charts were introduced briefly in the previous column (October 2015). Read More

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Time-Efficient Execution of Rheological Tests in Oscillation With an Easy-to-Use Quality Control Rheometer

Glycoxidative Modification of Adenosine in Relation to Diabetes and Obesity: Detection of Carboxymethyl-Adenosine in Biological Samples

Electronic DNA Sample Processing Preserves Evidence Integrity in the Forensics Laboratory

A DNA-Based Screening Assay to Streamline Sexual Assault Sample Processing

Use of Weighted Least Squares and Confidence Band Calibration Statistics to Find Reliable Instrument Detection Limits for Trace Organic Chemical Analysis

Simple Cell Imaging for Complex Research

Microbiological Testing Using Nutrient Pad Sets for Quality Assurance of Beverages

Statistics in the Laboratory: A New American Laboratory Column

Five Ways to Improve the Workflow and Financial Health of the Laboratory

Quantitative Analysis of H2A.X and ATM DNA Damage Signals Using Benchtop Flow Cytometry

Examining the Multiple Parameters of Glycolytic Activity

Recent Advances in ICP Spectrometers

In-House Pipette Calibration: The Lean Way

Innovative Sample Prep Removes Lipids Without Losing Analytes

The Road to Improved Next-Generation Sequencing Through Innovative PCR Instrumentation

Getting the Most Out of Limited Samples: A PCR Workflow for Monitoring Gene Expression

Maple Syrup Color Analysis Using UV/VIS Spectrophotometry

Optical Tweezers for Single-Cell, Multicellular Investigations in the Life Sciences

A Clearer View of 3-D Cell Culture: Optimizing Fluorescence Imaging and Analysis

Statistics in the Laboratory: Control Charts, Part 1

Product Guide

Micromachined HPLC Columns Can Revolutionize Proteomics Workflows

Buyer's Guide: GC-MS for Monitoring Environmental Pollutants

Refocusing the Lens of Cancer Screening

Study: NGS Should Be Go-to Technology on Day Zero of the Next Pandemic

Overcoming Common Challenges in Sample Viability for Single-Cell Research