Application Notes

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Measuring Absolute Molar Mass Using UHPLC SEC-MALS
Friday, June 13, 2014
Sophia Kenrick Aym Berges
The characterization of aggregates or fragments in a biomolecular sample for applications such as bioanalytical chemistry and clinical diagnostics has traditionally been carried out using size ... Read More
Best Practices for the Use of Micropipets
Friday, June 13, 2014
A. Björn Carle Doreen Rumery George Rodrigues
Every day, air-displacement pipets are used to quantitatively dispense sample and reagent aliquots for reaction, routine analyses, and specialized tests. Read More
Thorough Risk Assessment Supports At-Scale Process Safety
Wednesday, July 16, 2014
Urs Groth
It goes without saying that in any manufacturing environment no one sets out to design an unsafe process. However, it is not enough to ensure a process will be safe under normal operating conditions. Read More
An Economical Alternative to Rheological Characterization
Tuesday, July 29, 2014
Tien T. Dao Jeshwanth K. Rameshwaram
Rheological characterization continues to gain importance in the development of novel materials across a wide variety of industries. Historically, rheological characterization required a significant ... Read More
Electrophoresis 2.0: Faster, Stronger, and More Reproducible
Monday, August 04, 2014
Ryan Jensen Stefan Lehr Anton Posch
In 2010, researchers around the world were competing to finish the race to purify BRCA2, a protein whose mutant form is associated with more than 50% of hereditary breast cancer. But only one of ... Read More
LIMS-BPMS Coupling: A Novel Approach for Flexible End-to-End Workflow Automation in Life Science Laboratories, Part 2
Monday, August 04, 2014
Kerstin Thurow Silke Holzmüller-Laue Bernd Göde
This article illustrates the potential of coupling a business process management system (BPMS) and LIMS, was presented in Part 1 of this paper (Am. Lab. 2014, 46[4], 26–9). Part 2 highlights the ... Read More
Determination of Total Mercury Content in Wood Materials—Part 3: Miniaturization Using ICP-MS
Monday, August 04, 2014
Heidi Fleischer Kerstin Thurow Ellen Vorberg
High-throughput screening processes have become an essential tool in the pharmaceutical industry and clinical laboratory. High-throughput screening, or HTS, is used in drug discovery as well as in ... Read More
DNA Modification in Obese Persons: Detection and Estimation of Carboxymethyl-2’- Deoxyadenosine in Human Urine and DNA
Monday, September 01, 2014
Zeenat Ara Lila Dawnn Flowers Morgan Tubman-Jackson
Genetics, obesity, and lack of exercise play a vital role in the development of diabetes. Almost 80% of people with Type 2 diabetes are overweight. Read More
Enabling Cancer Research and Treatment With Droplet-Based Digital PCR Technology
Wednesday, September 03, 2014
George Karlin-Neumann
Cancer research is as necessary as ever, especially if we are to fulfill the promise of personalized (or “precision”) medicine based on specific cancer therapies directed to known molecular targets. Read More
Preparation of SMA/CaCO₃/CaCl₂@SiO₂ as a Fluid Loss Agent Based on PSA/Ca-MMT/CaCl₂@SiO₂
Thursday, September 04, 2014
Xiuhua Zheng Shiwei Yang Zhongli Lei
A novel inorganic/organic hybrid, highly temperature-resistant fluid loss agent had previously been reported by the Drilling Fluid Laboratory of China University of Geosciences. However, Ca-MMT (... Read More
Safety and Environmental Considerations in the Life Sciences Laboratory
Friday, September 05, 2014
Larry Gallagher
In life science laboratories and biotech firms, safety and environmental issues can be presented by the gases and cryogens utilized in the processes and controls. From simple oxygen deficiency that ... Read More
Microscopy for Materials Characterization: Illuminating Structures With Light and Electrons
Tuesday, September 09, 2014
Elaine F. Schumacher
Engineered materials abound in products that we use every day. They can range from a bulk material like the glass in a window to a dispersion of titanium dioxide nanoparticles in a sunscreen ... Read More
Portable Visible Absorption Spectrometry: Two Dimensions Instead of One
Wednesday, September 10, 2014
Alexander Scheeline
Think of a visible absorption spectrometer or a visible fluorimeter. What do you see? A scanned diffraction grating and photomultiplier? Read More
Analysis of Protosappanin B in Sappan Lignum by Capillary Zone Electrophoresis
Tuesday, September 23, 2014
Luzhi Sui Xiangqian Hou Xinmin Li Dunqing Wang
Sappan Lignum, the dried heartwood of Caesalpinia sappan L, has been used as an herbal medicine since ancient times. Sappan Lignum promotes blood circulation; removes blood stasis; reduces swelling, ... Read More
Determination of Sulfonamides in Chicken Liver by Capillary Electrophoresis with an In-Column Fiber-Optic LED-Induced Fluorescence Detector
Tuesday, September 30, 2014
Lihong Guo Dan Xiao Martin M.F. Choi
Sulfonamides (SAs) are a class of synthetic antimicrobial compounds with a broad spectrum. As shown in Figure 1, they all contain the same chemical structure of an unsubstituted amino on a benzene ... Read More
Application of Porous Nano-Calcium Titanate in Preconcentration of Heavy Metals in Water
Wednesday, October 15, 2014
Dong Zhang Yan Li
Heavy metal pollution in water has been a public concern for decades.Heavy metals, which include lead, cadmium, mercury, chromium, zinc, copper, and nickel, are highly toxic with hidden pollution, ... Read More
Top Considerations When Automating Your Real-Time PCR Workflow
Thursday, October 16, 2014
Jennifer Reed Kim Petro
With the increasing importance of large-scale data generation, many pharmaceutical labs are using robots to speed data collection. One such strategy is to automate the real-time PCR workflow. Read More
Detecting and Managing Water Contaminants in the Laboratory
Thursday, October 16, 2014
Jim Keary
Water purity is a fundamentally important factor in many laboratories, yet it is frequently overlooked. Researchers use water in most lab processes, and poor water quality can quickly lead to ... Read More
Use of Environmental Transmission Electron Microscopy to Study the Dynamic, Catalytic Reactions on Metal Nanoparticle Catalysts
Thursday, October 16, 2014
Joerg Jinschek
Prof. Seiji Takeda leads a research group in the Department of Nanocharacterization for Nanostructures and Functions of the Nanoscience and Nanotechnology Center at the Institute of Scientific and ... Read More
A Portable CGE-Based Biomolecule Detection System Using a Smartphone App for Operation via WiFi
Monday, October 27, 2014
Varouj Amirkhanian Eric Tsai Allen Chi Myron Yu Hsinhan Huang
Most bioseparation and detection tools used in the laboratory employ slab gel-based electrophoresis technologies, which have routinely been used for the analysis of biomolecules (i.e., DNA, RNA, ... Read More

Sort

Measuring Absolute Molar Mass Using UHPLC SEC-MALS

Best Practices for the Use of Micropipets

Thorough Risk Assessment Supports At-Scale Process Safety

An Economical Alternative to Rheological Characterization

Electrophoresis 2.0: Faster, Stronger, and More Reproducible

LIMS-BPMS Coupling: A Novel Approach for Flexible End-to-End Workflow Automation in Life Science Laboratories, Part 2

Determination of Total Mercury Content in Wood Materials—Part 3: Miniaturization Using ICP-MS

DNA Modification in Obese Persons: Detection and Estimation of Carboxymethyl-2’- Deoxyadenosine in Human Urine and DNA

Enabling Cancer Research and Treatment With Droplet-Based Digital PCR Technology

Preparation of SMA/CaCO₃/CaCl₂@SiO₂ as a Fluid Loss Agent Based on PSA/Ca-MMT/CaCl₂@SiO₂

Safety and Environmental Considerations in the Life Sciences Laboratory

Microscopy for Materials Characterization: Illuminating Structures With Light and Electrons

Portable Visible Absorption Spectrometry: Two Dimensions Instead of One

Analysis of Protosappanin B in Sappan Lignum by Capillary Zone Electrophoresis

Determination of Sulfonamides in Chicken Liver by Capillary Electrophoresis with an In-Column Fiber-Optic LED-Induced Fluorescence Detector

Application of Porous Nano-Calcium Titanate in Preconcentration of Heavy Metals in Water

Top Considerations When Automating Your Real-Time PCR Workflow

Detecting and Managing Water Contaminants in the Laboratory

Use of Environmental Transmission Electron Microscopy to Study the Dynamic, Catalytic Reactions on Metal Nanoparticle Catalysts

A Portable CGE-Based Biomolecule Detection System Using a Smartphone App for Operation via WiFi

Product Guide

Micromachined HPLC Columns Can Revolutionize Proteomics Workflows

Buyer's Guide: GC-MS for Monitoring Environmental Pollutants

Refocusing the Lens of Cancer Screening

Study: NGS Should Be Go-to Technology on Day Zero of the Next Pandemic

Overcoming Common Challenges in Sample Viability for Single-Cell Research