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Title
Impact of Weighing Accuracy and Data Integrity in Forensic Drug Analysis
Friday, November 10, 2017
Tucker Rubino
Klaus Fritsch
Thomas Rohrer
To stay compliant with ever-changing regulations and withstand any challenge in court, it is critical for managers and scientists in forensic laboratories to be well-informed about the key issues ...
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Isothermal Titration Calorimetry: An Indispensable Tool for Biological Pathway Research and Drug Development
Monday, October 02, 2017
Verna Frasca
As our knowledge of the genetic and molecular basis of disease continues to grow, drug development programs focus increasingly on those proteins associated with disease states.
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ASTM-Approved Method for Simultaneous Determination of Total Nitrogen and Phosphorus in Wastewater by Ion Chromatography
Monday, October 02, 2017
Jeff Rohrer
Richard Jack
Brian De Borba
As natural elements in aquatic ecosystems, nitrogen and phosphorus support the growth of algae and aquatic plants, providing food and shelter for fish and other organisms.
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Failure Analysis of Rubber Materials Using Pyrolysis-GC/MS
Wednesday, February 14, 2018
Rojin Belganeh
William Pipkin
Pyrolysis GC/MS has a wide variety of applications for identifying the organic composition of unknown samples by providing detail information about the compounds present in a sample.
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Innovations in Metals Analysis Optimize the Process
Thursday, January 18, 2018
David Smith
From reagent addition to sample digestion, faster, and safer metals digestion can be achieved with the latest technology.
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GC/VUV: A Novel Tool for the Identification and Quantitation of Gas-Phase Analytes
Monday, February 19, 2018
Paul Johnson
VUV spectroscopy has unique capabilities that address many of the challenges inherent to GC separations.
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Best Practices When Changing From HPLC to TOC Analysis for Cleaning Validation
Thursday, January 18, 2018
Lukas Swanson
Cleaning process/sample compatibility, cleaning limit acceptance criteria, and product recovery/solubility should be considered when investigating the feasibility of TOC analysis for CV.
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Centrifugation: Best Practices for Reliable, Reproducible Results
Wednesday, February 14, 2018
Hugh Tansey
Laboratories can benefit from advances in centrifuge functionality and performance, as well as ergonomics and ease-of-use.
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A Portable CGE System for Cell Free DNA Detection
Monday, January 29, 2018
Varouj Amirkhanian
Eric Tsai
Alice Lin
Geoffrey Routh
A capillary gel electrophoresis system provides cost-effective cfDNA analysis for the noninvasive detection of cancer and prenatal genetic testing.
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Testing Viscosity in Chocolates: New Methods to Reliably Meet Industry Standards
Wednesday, February 14, 2018
Klaus Oldoerp
The latest advancements in rheological instrumentation have enabled food manufacturers to test viscosity in chocolate products faster and more reliably than previously.
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Statistics in the Laboratory: The Limit of Quantitation
Thursday, January 18, 2018
Stanley N. Deming
In the two previous columns, we discussed the limit of detection LD, the minimum signal strength above which we can state with at least a given level of confidence (e.g., =99.95%) that analyte is ...
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Optical Efficiency Effects on Infrared Diffuse Reflection Spectroscopy Signal-to-Noise Ratio
Thursday, May 03, 2018
Dalia K. Maraoulaite
Robert L. White
This paper describes the impact of typical DRIFTS optical configurations on measurement SNR.
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On-Scene HAZMAT Response and Chemical Confirmation With GC/MS
Tuesday, March 27, 2018
Philip Tackett
Two situations are presented in which a person-portable GC/MS can be used to provide confirmatory chemical identification.
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Multistep Thermal Characterization of Liquid-Filled Capsules and Medication Packaging Using GC/MS
Friday, March 23, 2018
Karen D. Sam
Multistep thermal sampling allowed the analysis of both volatile and nonvolatile constituents directly to the gas chromatograph.
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Integrating GC/TOF Exposome Profiling and Genetic Disease Screening to Provide a Holistic Perspective on Honey Bee Health
Friday, March 23, 2018
Sassicaia J. Schick
Robert L. Broadrup
Christopher Mayack
Helen K. White
Anthony Macherone
The exposome generated by gas chromatography/quadrupole time-of-flight analysis was integrated with semiquantitative PCR disease screening to establish chemical profile signatures and associations ...
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A Blood Separation Device That Eliminates Centrifugation and Reduces Preanalytical Errors and Turnaround Times
Friday, February 09, 2018
Darren Lee
Clinical diagnostic testing laboratories are under increased pressure to continually provide accurate results for each patient tested while reducing turnaround times (TATs).
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Why Choose A Cone Spindle for Viscosity Measurement?
Monday, March 26, 2018
Robert G. McGregor
Key considerations for selecting a rotational viscometer include how much sample material is available for testing, whether a broad range of shear rates used in the test method is important, whether ...
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UCMR4, Microcystins Analysis, and High-Resolution Mass Spectrometry for Confidence in Identity Confirmation
Monday, March 26, 2018
Craig Butt
April Quinn-Paquet
K.C. Hyland
Quantitation of a suite of microcystins and nodularin was demonstrated using LC-MS/MS on a QTOF system.
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Centrifugal Partition Chromatography: The Key to Green Preparative Chromatography
Monday, March 26, 2018
Gregoire Audo
Centrifugal partition chromatography is a sustainable solution for reducing the environmental impact of preparative chromatography while reducing production costs.
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Routine Maintenance in ICP-MS: Critical When Monitoring Elemental Impurities in Pharmaceuticals
Tuesday, May 01, 2018
Robert Thomas
Routine maintenance is critical in ICP-MS, and this article provides guidance on keeping the sample introduction clean.
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