Application Notes

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Proper Monitoring of Refrigerators and Freezers to Protect Valuable Biomedical Inventory
Friday, January 20, 2017
Rob Fusco
Best practices for cold storage must be followed to protect valuable samples. Important goals are to avoid degradation, which stems from high and low temperature extremes, and prevent loss of potency ... Read More
High-Throughput VOC and Inorganic Gas Analysis: Automated SIFT-MS
Friday, January 20, 2017
Mark J. Perkins Vaughan S. Langford Murray J. McEwan
A sensitive technique called selected ion flow tube mass spectrometry (SIFT-MS) allows the direct, real-time monitoring of inorganic gases and volatile organic compounds (VOCs), with no need to ... Read More
siRNA Knockdown: Implementing Negative Controls in Antibody QC
Friday, January 20, 2017
Will Olds
This article presents an overview of short interfering RNA (siRNA) knockdown, a powerful negative control method, followed by tips to optimize siRNA transfection experiments. Read More
Bringing Raman Spectroscopy to the Undergraduate Laboratory
Friday, January 20, 2017
Brian Marquardt Giora Proskurowski
Designed specifically for the educational environment, a Raman tool incorporates a safe way to operate laser in a durable, open package, offered at about a third of the price of a traditional Raman ... Read More
Compact HPLC Systems for the Analysis of Pesticides, Dyes and Drugs
Friday, January 20, 2017
Vlad Orlovsky Yury Zelechonok Konstantin Tchalukov
The analyzer described in this article provides fast analysis of food dyes commonly used in products in the beverage and pharmaceutical industries, as well as high-resolution separation of a complex ... Read More
Integration of a Dilution Module in a Mass Spectrometry-Based Online Reaction Monitoring System
Friday, January 20, 2017
Heidi Fleischer Kerstin Thurow Vinh Quang Do Dany Hoffmann
A dilution module based primarily on a mass rate attenuator solves the problem of high concentration solution to the mass spectrometer. The low-flow compensation approach was used to circumvent the ... Read More
Comparison of ICP-QQQ and MP-AES to Alternative Atomic Spectroscopy Techniques
Friday, February 17, 2017
Shane Elliott
This article gives an overview of the various atomic spectroscopy techniques available to address a range of applications in environmental science, food and agriculture, life sciences and academic ... Read More
Refrigeration Practices for Biological Sample Preservation
Friday, February 17, 2017
Robert Sandor
Preservation of biological samples such as tissues, plasma and forensic and pathology specimens relies on maintaining proper storage temperatures and on the type of sample and analysis to be done. ... Read More
Improved Method to Quantitate Gluten in Purified Wheat Starch
Friday, February 17, 2017
Katharina Anne Scherf Peter Koehler
A new HPLC method may be applied as a confirmatory method to ELISA, particularly to check for the presence of glutenins in WSt rendered gluten-free. Read More
Super-Resolution Microscopy Techniques Combine to Clarify Spatiotemporal Structure of the Endoplasmic Reticulum
Friday, February 17, 2017
Robert L. Stevenson, Ph.D.
Super-resolution microscopy encompasses several new techniques for direct spatiotemporal imaging of structural features much smaller than the diffraction limit of light. The endoplasmic reticulum (ER)... Read More
Individual Cell Analysis for Protein Expression and Cell Health Markers
Tuesday, March 21, 2017
Robin T. Clark
The Muse instrument uses microcapillary fluidics and preoptimized reagents to create an inexpensive, compact, portable cell analyzer that requires minimal setup and no expertise to operate. Read More
Design and Use of Multiplex Immunoassays Based on Oligonucleotide Tethering
Tuesday, March 21, 2017
Robert S. Matson
Oligonucleotide tethering offers an unconventional approach to antibody immobilization. Read More
Lab Vacuum Pumps: Selection and Protection
Friday, February 17, 2017
Peter Coffey
Useful tips are given for choosing the right vacuum pump for the lab. Read More
Automated Liquid Handling Facilitates Immunofluorescence Assay Optimization
Tuesday, March 21, 2017
Wendy Goodrich
This article describes the high-resolution capability of an automated imager equipped with oil immersion microscope objectives. Read More
GC×GC-MSq: A New Tool in Arson Investigation
Tuesday, March 21, 2017
Clifford M. Taylor A. Kirk Rosenhan Joey M. Raines Jose M. Rodriguez
Two-dimensional gas chromatography-quadrupole mass spectrometry (GC×GC-MSq) is a powerful tool for complex arson analysis. Read More
Identifying Whiskey Adulteration by GC/MS Through Chemical Profiling and Differential Analysis
Tuesday, March 21, 2017
Paul Silcock Dominic Roberts Jana Hajslova Jana Pulkrabova
GC/MS used with statistical analysis and structural elucidation software rapidly determines the complex chemical composition of whiskies. Read More
A Redesigned Confocal Microscope for Super-Resolution Microscopy
Tuesday, May 09, 2017
Erik Manders Peter Drent Ronald Breedijk
A simple optical redesign converts a standard confocal microscope to a super-resolution microscope. Read More
Scalable Synthesis Technology
Wednesday, June 07, 2017
Philipp Wenter
A DNA synthesis platform addresses the need for smaller-scale oligo production without sacrificing quality, accuracy or turnaround time. Read More
Advances in Single-Cell Biology Using Mass Spectrometry
Wednesday, March 22, 2017
Rohan Thakur
Single-cell analysis by MS has proven extremely valuable in discovering unique neuropeptides in a broad range of animal models, from complex mammalian species to simpler organisms such as sea slugs. Read More
Best Practices: Incubators
Monday, May 08, 2017
Nancy Klimpel
Important parameters to consider when selecting an incubator are temperature accuracy, stability and uniformity. Read More