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Advances in Microscale Protein Fractionation and Analysis
Monday, January 01, 2007
Julie S. Hey
Fractionation is an essential step in the identification of proteins and their subsequent structural characterization. read more
High-Efficiency FAMEs Analyses Using Capillary GC
Monday, January 01, 2007
Allen K. Vickers
During the past few decades, a variety of theories concerning the hazards and benefits of dietary fats have been postulated, some of which seem to be contradictory. read more
Fast, Practical GC and GC-MS
Monday, January 01, 2007
Jaap de Zeeuw Martine Barnes
Shortening run times is a welcome exercise for many laboratories, especially when sample throughput needs to be increased. read more
Ultrasensitive Measurement of Protein and Nucleic Acid Biomarkers for Earlier Disease Detection and More Effective Therapies
Friday, January 19, 2007
Gregory Shipp
It is a universal fact substantiated by decades of biopharmaceutical research: the earlier a disease is detected, the more likely treatments will be effective in alleviating or stabilizing the disease... read more
Improved Column Chromatography Performance Using Arginine
Thursday, February 01, 2007
Daisuke Ejima Kouhei Tsumoto Tsutomu Arakawa
Protein purification and analysis using column chromatography is facing new challenges because of increasing demands in the proteomic and biotechnology fields. read more
The Nanoliter Syringes
Thursday, February 01, 2007
Andrew D. Sauter
Following an informal collaboration with Affymax (Palo Alto, CA), Agilent Technologies (Palo Alto, CA), and Chem-Space Associates (Pittsburgh, PA), studying electrospray ionization 1 (ESI), the ... read more
Statistics in Analytical Chemistry: Part 25—Calibration Summary
Thursday, February 01, 2007
David Coleman Lynn Vanatta
In a modern chemical-analysis laboratory, virtually all of the testing equipment must be calibrated periodically. read more
Experimental Variables in GC×GC: A Complex Interplay
Thursday, February 01, 2007
James Harynuk Tadeusz Górecki
Comprehensive two-dimensional gas chromatography (GC×GC) has been enjoying increasing attention in recent years. read more
Minimizing Liquid Delivery Risk: Pipets as Sources of Error
Thursday, March 01, 2007
Richard Curtis
This is the first in a series of articles entitled, “Minimizing Liquid Delivery Risk,” addressing the most common causes of liquid delivery error and providing guidance on how to address and overcome... read more
A Charged Aerosol Detector That Reduces Vaccine Development Time
Thursday, March 01, 2007
Jerry Fireman Darrick Carter Mary Wallace
The Infectious Disease Research Institute (IDRI, Seattle, WA) is a not-for-profit corporation that has developed the first defined vaccine for leishmaniasis, which is now in clinical trials, in ... read more
Fused Core Particles for HPLC Columns
Sunday, April 01, 2007
Joseph J. Kirkland Timothy J. Langlois Joseph J. DeStefano
In recent years, there has been a strong movement toward the use of HPLC columns with smaller particles. read more
Rapid, Quantitative Analysis of Multiple Mycotoxins by Liquid Chromatography Tandem Mass Spectrometry
Sunday, April 01, 2007
Mahalakshmi Rudrabhatla Jason S. Wood
The classical example of detrimental effects caused by bacteria, such as E. coli or Bacillus Anthracis, is through invasion of the host. read more
New Technologies in Human Genetic Analysis
Wednesday, April 04, 2007
Mark E. Samuels Brent Higgins Sylvie Provost Julien Marcadier Christian Blouin Sharen Bowman Marie-Pierre Dubé
Human genetics has benefited in the last decade from spectacular technological advances in DNA analysis. read more
Use of Dual-Selectivity IC-ESI-MS for the Separation and Detection of Anionic and Cationic Arsenic Species
Tuesday, May 01, 2007
Rosanne W. Slingsby Rida Al-Horr Christopher A. Pohl Joung Hae Lee
There are times when an analytical challenge demands a solution that reaches beyond standard methodologies. read more
Establishing a Microbial Control Strategy for Active Pharmaceutical Ingredients
Friday, June 01, 2007
Anne M. Warner John D. Stafford Robert E. Warburton
In the pharmaceutical industry, defining the control strategy for a new active pharmaceutical ingredient (API) is a main goal during development of the process for its commercial manufacture. read more
Multidetection Microplate Readers: Filter-Based, Monochromator-Based. . .or Both?
Friday, June 01, 2007
Xavier Amouretti
The appeal of multidetection microplate readers is easy to understand: they combine multiple measurement technologies such as absorbance, fluorescence,and luminescence into one compact instrument. read more
Minimizing Liquid Delivery Risk: Automated Liquid Handlers as Sources of Error
Friday, June 01, 2007
Keith J. Albert
This is the second in a series of articles entitled, “Minimizing Liquid Delivery Risk,” addressing the most common causes of liquid delivery error and providing guidance on how to address and overcome... read more
Statistics in Analytical Chemistry: Part 26—Detection Limits: Editorial Comments and Introduction
Friday, June 01, 2007
David Coleman Lynn Vanatta
We believe that detection limits (DLs) should go away. read more
Acidic Digestion of Soils to Determine Mercury Concentration
Friday, June 01, 2007
Pamela F. Heckel Tim C. Keener
Soils are notoriously heterogeneous and difficult to analyze. The authors developed a digestion method to extract mercury from clay soils using relatively inexpensive cold vapor atomic absorption ... read more
Calorimetry: Getting the Winning Combination
Wednesday, July 18, 2007
Ed Sullivan
Ultrasensitive calorimetric instruments for measuring very small heats of reaction at constant temperature (isothermal titration calorimetry [ITC]) and small heat effects induced by temperature (... read more