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Title
Protein Stability Monitored by Fourier Transform Infrared Spectrometry
Thursday, June 01, 2006
Michael S. Bradley
Degradation of proteins during storage or processing is a major concern in both manufacturing and research.
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Statistics in Analytical Chemistry: Part 22—Lack-of-Fit Details
Thursday, June 01, 2006
David Coleman
Lynn Vanatta
Because of popular demand from readers, this installment will discuss the principles and calculations that underlie the lack-of-fit (LOF) test.
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High-Purity Water and pH
Thursday, June 01, 2006
Estelle Riché
Aude Carrié
Nicolas Andin
Stéphane Mabic
pH influences the rate of many chemical and enzymatic reactions.
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Cost Benefit Analysis of a Multicapillary Electrophoresis System
Thursday, June 01, 2006
Varouj Amirkhanian
Ming Lui
Andras Guttman
Eszter Szantai
Today’s genomics laboratories require high throughput, cost-effectiveness, detection sensitivity, and high resolution.
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Rapid Determination of Nine Chemotherapeuticals in Animal Feed by HPLC-DAD Using a Monolithic Column
Thursday, June 01, 2006
Rita Bibi
Gloria R. Tovo
Ivan Pecorelli
Chemotherapeuticals as feed additives were widely used in the European Union to prevent and control many diseases in food-producing animals,
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Design Strategies for Hyper-Clean Laboratories
Tuesday, August 01, 2006
Thomas Harvath
Nanotechnology has been aptly described as the science of building a structure one atom at a time.
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Impact of HTS on Multidetection Microplate Readers and Benefits For Life Science Research Laboratories
Tuesday, August 01, 2006
Xavier Amouretti
The basic concept behind high-throughput screening (HTS) is a numbers game: If one has the technical ability to test thousands upon thousands of potential drug compounds against a specific target, it ...
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Microfiltration Technology: A Sensible Approach to Automating Sample Preparation
Tuesday, August 01, 2006
William E. Coville
Mason Loika
In the world of laboratories, the discerning eye of an efficiency expert must wince while witnessing sample preparation.
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Expanding the Limits of Closed- Vessel Microwave Sample Preparation
Thursday, August 10, 2006
Kenneth J. Borowski
Charles Schoenfeld
Analytical chemists have long known that closed-vessel microwave sample preparation techniques are the most reliable way to achieve high-quality digestions—i.e., clear, precipitate-free solutions...
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A Valve Switching Ion Chromatography System With Integrated Automation Management
Friday, September 01, 2006
Richard Jack
Rong Lin
Brian De Borba
Kannan Srinivasan
Yoko Sekiguchi
Yuichi Nakanishi
Kazue Yoshimura
Valve switching applications are becoming popular in ion chromatography (IC). Example applications include matrix diversion or matrix elimination prior to analysis of trace components.
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Peptide De Novo Sequencing With MALDI TOF/TOF: A Simple Approach Using Sulfonation Chemistry
Thursday, September 07, 2006
Paolo Conrotto
Ulf Hellman
One of the main focuses of the scientific community, now that major advances have been achieved in the comprehension of genome organization, has become the study of proteins, including their structure...
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Accurate Determination of Amino Acids in High-Carbohydrate-Containing Samples
Sunday, October 01, 2006
Valoran P. Hanko
Jeffrey S. Rohrer
In a high-sensitivity amino acid analysis (AAA) technique that does not require sample derivatization, both amino acids and carbohydrates are separated by high-performance anion-exchange ...
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A Convenient Sample Introduction System for ICP, ICP-MS, and AA
Sunday, October 01, 2006
Roger McLaughlin
Paula Cheese
Min Ding
Adam Ptolemy
April Conn
Ian Brindle
Sample introduction has been a problem for analytical chemists for decades. In 1984, Richard Browner and Andrew Boorn went so far as to call sample introduction "The Achilles’ Heel of Atomic ...
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Statistics in Analytical Chemistry: Part 23—Degrees of Freedom in the Lack-of-Fit Test
Sunday, October 01, 2006
David Coleman
Lynn Vanatta
In the previous article (Part 22, American Laboratory, June/July 2006), the details behind the lack-of-fit (LOF) test were discussed.
read more
A New Paradigm for the Development of Fluorescent RNA Imaging Technology Using Synthetic Molecules
Monday, October 02, 2006
Kazunori Koide
In vivo protein imaging technology has been greatly advanced over the last decade by the development of green fluorescent protein (GFP) and its derivatives as investigational tools.
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A Single Molecular Multianalyte Fluorescent Probe and Its Application to Imaging Intracellular Multianalyte Dynamics
Tuesday, October 10, 2006
Hirokazu Komatsu
Kotaro Oka
Koji Suzuki
Single molecular multianalyte sensors are molecular sensors that can determine multiple analytes by recognition of the various analytes based on the difference of the spectral changes.
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Celebrating 25 Years of Scanning Probe Microscopy and the Work of Kumar Wickramasinghe
Wednesday, November 01, 2006
Jezz Leckenby
In 1981, two research scientists from IBM’s European research facility in Rueschlikon, Switzerland, made a discovery that would help change the face of the world today.
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Understanding the Links Between Rheology and Particle Parameters
Wednesday, November 01, 2006
Steve Carrington
Adrian Hill
The rheology of a suspension or dispersion relates directly to many parameters of commercial interest.
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Statistics in Analytical Chemistry: Part 24—Glossary
Friday, December 01, 2006
David Coleman
Lynn Vanatta
Since the beginning of this series of articles, the central topic has been calibration and its associated uncertainty.
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Attomole Quantitative Chemiluminescence for Molecular Diagnostics
Monday, January 01, 2007
Aaron Ho
Jian Tajbakhsh
The study and use of bioluminescence and chemiluminescence have increased dramatically in recent years.
read more
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