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New Approach to 3-D Imaging of Biological Materials Provides Isotropic Resolution Down to a Few Nanometers
Visualizing the three-dimensional (3-D) architecture of cells and tissues is essential for understanding the relationships between structure and function in biological systems.
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Wyatt’s International Light Scattering Colloquium Focuses on the Nano World
The 24th International Light Scattering Colloquium, which attracted about 70 scientists to the Biltmore Hotel on Butterfly Beach in Santa Barbara, Calif., November 3–4, focused on analytical ...
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Automation Enhances Next-Generation Sequencing Workflows
Powerful next-generation sequencing (NGS) platforms have led to the development of large-scale genome initiatives like the 100,000 Genomes Project, The Cancer Genome Atlas (TCGA), International ...
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Super-Resolution Microscopy Helps Extend Optical Observation Beyond Its Theoretical Boundaries
Scientists have long needed to view structures and processes that cannot be resolved via traditional optical microscopy.
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Smart Sample Prep in Chromatography: An Automated Liquid–Liquid Extraction Technique for Metabolomics Analysis
As laboratories continue to be asked to increase productivity and the analysis power that is available with advanced chromatography systems continues to grow, the focus for many scientists is firmly ...
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A Novel Hydrogel-Based Approach for Cell Isolation, Purification and Release
The purification and enrichment of specific cell populations from complex starting samples is a critical component of multiple life science workflows.
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Long-Range Sequencing is Required to Unlock the Full Genome
Next-generation sequencing (NGS) provides unprecedented access to one of biology’s greatest mysteries—the genome.
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Long Reads and the Return of Reference Genomes
The availability of inexpensive, massively parallel short-read sequencers shifted the focus of high-quality reference genome production to resequencing and draft genome assemblies, emphasizing ...
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Transitioning From HPLC to UHPLC of Proteins
Since the introduction of ACQUITY UPLC (Ultra Performance Liquid Chromatography) by Waters (Milford, Mass.) over a decade ago, there has been increased interest in the effects of high pressure on ...
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Using a Standard Bath Circulator as a Calibration Device
This technical note will review the considerations for using a standard bath circulator or water bath as a calibration instrument instead of a purpose-built calibration bath.
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Equipping Researchers in the Developing World
Having shipped 87 tons of scientific equipment to 35 institutions based in 24 countries in the developing world since 2003, the nonprofit organization Seeding Labs has a very focused and motivated ...
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The Benefits of HPLC Coupled With Mass Spectrometry for the Direct Quantitation of Underivatized Amino Acids
Amino acids are critical biological components having multiple metabolic functions, particularly when linked together to form proteins, and have any number of important roles.
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Highlights From SLAS2016
Despite a blizzard in the Eastern United States, 6293 scientists—an increase of about 25% from the conference’s previous high—were able to travel to sunny San Diego to discuss laboratory automation ...
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Microplate Reader Wins Best New Life Sciences Product Award
The Synergy Neo2 multi-mode microplate reader from BioTek Instruments is the winner of the Best New Life Sciences Product for 2015 as part of the annual Scientists’ Choice Awards sponsored by ...
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Advances in Separation Science at Pittcon 2016
While spectacular developments in chemical imaging and spectroscopy continue to entice the market, separation science remains a key enabling technology.
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