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Our Life and Death Relationship with Bacteria
Monday, November 17, 2014
We have a symbiotic relationship with bacteria. Many are essential for life, but a few can be lethal. Plus, the bacteria play an essential role in returning us to dust.
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True Hypoxia Replication: Creating Optimal Conditions for Cell-Based Research
Monday, November 10, 2014
There is a rapidly growing need for systems capable of creating precise, reproducible, and physiologically relevant cell environments in the laboratory in order to enable accurate analysis of both ...
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An Improved Method to Generate Virus-Free Human iPSCs
Monday, November 03, 2014
Induced pluripotent stem cells (iPSCs) are offering new opportunities in both research and clinical applications. Researchers are using these cells for drug and toxicity screening, as well as for ...
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A Portable CGE-Based Biomolecule Detection System Using a Smartphone App for Operation via WiFi
Monday, October 27, 2014
Most bioseparation and detection tools used in the laboratory employ slab gel-based electrophoresis technologies, which have routinely been used for the analysis of biomolecules (i.e., DNA, RNA, ...
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Semantic Web Technologies as a Key to Successful Federation of Data in Life Science Organizations
Monday, September 22, 2014
The RDF Semantic Web has become an important player over the years in regard to federating different data sources using a common query federation tool, SPARQL. W3C SPARQL is now established as a ...
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Success of the Third sbv IMPROVER Network Verification Challenge
Wednesday, September 17, 2014
The accomplishment of the Human Genome Project in 2001 created the illusion that the time would soon come when everyone would go to the doctor’s office, read his or her genome, and get treatment ...
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Enabling Cancer Research and Treatment With Droplet-Based Digital PCR Technology
Wednesday, September 03, 2014
Cancer research is as necessary as ever, especially if we are to fulfill the promise of personalized (or “precision”) medicine based on specific cancer therapies directed to known molecular targets.
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Electrophoresis 2.0: Faster, Stronger, and More Reproducible
Monday, August 04, 2014
In 2010, researchers around the world were competing to finish the race to purify BRCA2, a protein whose mutant form is associated with more than 50% of hereditary breast cancer. But only one of ...
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AES 2013: Annual Meeting of the AES Electrophoresis Society
Monday, August 04, 2014
The field of electrophoresis encompasses separations of molecules or particles based on their migration in an applied electric field. Electrophoresis now includes a wide variety of techniques ...
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LIMS-BPMS Coupling: A Novel Approach for Flexible End-to-End Workflow Automation in Life Science Laboratories, Part 2
Monday, August 04, 2014
This article illustrates the potential of coupling a business process management system (BPMS) and LIMS, was presented in Part 1 of this paper (Am. Lab. 2014, 46[4], 26–9). Part 2 highlights the ...
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Book Review: The Future of the Mind
Monday, July 14, 2014
On April 2, 2014, President Obama announced the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative, with projected funding of over $100 million. This seems well and good,...
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Book Review: Aggregation of Therapeutic Proteins
Tuesday, July 01, 2014
As an editor for American Laboratory, I responded to our subscribers for help in detecting and controlling aggregation of therapeutic proteins. On the one hand, I was amazed at the complexity and ...
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The Importance of an Integrated Informatics Solution for Life Science Organizations and Keys to Successful Deployment
Monday, June 16, 2014
The exorbitant cost of bringing a new pharmaceutical product to market in the U.S. is well documented, with estimates as high as 12 years and $11 billion. There are many factors that drive this cost, ...
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Measuring Absolute Molar Mass Using UHPLC SEC-MALS
Friday, June 13, 2014
The characterization of aggregates or fragments in a biomolecular sample for applications such as bioanalytical chemistry and clinical diagnostics has traditionally been carried out using size ...
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Best Practices for the Use of Micropipets
Friday, June 13, 2014
Every day, air-displacement pipets are used to quantitatively dispense sample and reagent aliquots for reaction, routine analyses, and specialized tests.
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