Application Notes

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$A Fully Automated Benchtop X-Ray Diffractometer for Structure Determination of Small Molecules$
A Fully Automated Benchtop X-Ray Diffractometer for Structure Determination of Small Molecules
Tuesday, March 17, 2009
Michael Ruf
Single-crystal crystallography provides accurate and precise measurements of molecular dimensions in a way that no other science can begin to approach. Small-molecule crystallographers study ... Read More
A Flexible Imaging Detector for Nanoliter Volume Bioanalysis
Friday, March 20, 2009
David M. Goodall Pawel L. Urban
Most organic molecules, especially biomolecules, absorb light in the UV range with the response being proportional to their concentration. Read More
21st Century Gel Documentation in Research and Production Environments
Friday, March 27, 2009
John Pizzonia
Standard gel documentation has been performed for decades with some variation of the “camera on a stick” approach, that is, the camera and lens are positioned above the target pointed downward at the ... Read More
Automated ELISA Liquid Handling With a Combination Microplate Washer Dispenser
Friday, April 17, 2009
Paul Held Jason Greene
Many biochemical assays involve the addition of different reagent fluids interrupted by delays or incubations to allow for a reaction to occur. Read More
Evolving Products in the Homogenizing Field
Friday, April 17, 2009
Brian Archibald
As technology moves forward in laboratory research and development, new products are emerging within the field of sample preparation. Read More
Decoding the Nanoworld: Pushing the Envelope in Atomic Force Microscopy
Friday, April 17, 2009
Mario Viani Roger Proksch Jason Cleveland Monteith G. Heaton
Over the past decade, atomic force microscopy/scanning probe microscopy (AFM/SPM) has emerged as the leading tool for investigations at the nanoscale—doing everything from imaging, to compositional ... Read More
Selecting Centrifuge Consumables
Friday, April 17, 2009
Tammy Goodman
Selecting a centrifuge and rotor can sometimes feel like the easy part when faced with choosing the consumables in which to centrifuge samples. There are many suppliers of centrifuge tubes to choose ... Read More
A Chromatography Detector for Multicomponent Analysis of Macromolecules and Polymers
Friday, April 17, 2009
Jason Sanchez Paul Clarke Jean-Luc Brousseau
The properties of long-chain molecules and polymers are tailored to meet the demands of a specific application in a range of different ways. In the production of “smart” materials and other high-... Read More
Food Safety: The Value of LIMS in This Regulated Environment
Thursday, May 28, 2009
Colin Thurston
The U.S. Food and Drug Administration (FDA) has issued a number of regulations to ensure the safety of food manufactured, distributed, exported, and imported in the U.S. The Federal Food, Drug and ... Read More
A Novel Approach to 3-D Biological Sample Analysis Using a Dual-Beam FIB/SEM
Thursday, May 28, 2009
Ben Lich
Early interpretations of biological structures using film-based transmission electron microscopy (TEM) images were based on the analysis of two-dimensional TEM images, or by the painful reconstruction... Read More
Easy Transition From Assay Development to High-Throughput Screening
Thursday, May 28, 2009
Peter Banks Xavier Amouretti Karen Kleman-Leyer Brad Larson Tracy Worzella
A critical factor in achieving success with any assay is to ensure that the assay detection instrumentation is compatible with the reagents being used. Read More
Using a Purge-and-Trap Concentrator for Newly Proposed U.S. EPA Method 524.3
Thursday, June 18, 2009
Teri Dattilio
Purge-and-trap (P&T) concentration along with GC analysis is a widely used method for the detection of volatile organic compounds (VOCs). This methodology was developed to achieve the high sensitivity... Read More
Determination of Metal Impurities Present in Solar-Grade Bulk Silicon by ORS-ICP-MS
Thursday, June 18, 2009
Junichi Takahashi
Research into alternative energy sources is accelerating, with one of the most dynamic areas of interest being the development of devices to harness solar energy. Some industry experts, including the ... Read More
A Versatile Substrate Coated With Silver Nanoparticles for Surface-Enhanced Vibrational Spectroscopy
Thursday, June 18, 2009
Beng Guat Ooi Lijie Zhao Ngee-Sing Chong
Both infrared and Raman spectroscopic techniques are useful for probing the structure of complex molecules. However, they are typically not as sensitive as mass spectrometric techniques and hence have... Read More
An Improved Protocol for the Analysis of Alcohols by Direct Analysis in Real Time Mass Spectrometry
Thursday, June 18, 2009
James A Laramée H. Dupont Durst J. Michael Nilles Theresa R. Connell
It was previously reported that when Direct Analysis in Real Time (DART™) (JEOL USA, Inc., Peabody, MA) mass spectrometry was applied to the analysis of very pure alcohols, their mass spectra were ... Read More
ICP Spectrometry Coupled With a Separate Sampling and Excitation Accessory for Rapid Analysis of Impurities in Silver
Wednesday, July 01, 2009
George Buchbinder Nikolai Verblyudov Andrew Clavering
Silver is one of the oldest metals known to humanity and is still very important in minting, jewelry, and industry. Silver can be obtained from pure deposits and ores and, like other precious metals, ... Read More
Portable IR Analyzers: The Ideal Measurement Solution for Biofuels Blend Quality and Wastewater Testing
Wednesday, July 01, 2009
Sandra Rintoul
Two challenges facing the biofuels industry involve compliance with blend quality standards and wastewater regulations. According to a study done by the National Renewable Energy Laboratory, the chief... Read More
Use of Rotational Vane Rheometry to Solve Practical Problems
Saturday, August 01, 2009
David J. Moonay
Rheology is the study of the deformation of matter. A common definition is that rheology is the study of flow. Viscometry, in particular, is the measurement of viscosity or the resistance to flow. ... Read More
Sediment Standard Reference Materials
Saturday, August 01, 2009
Michele Schantz Rolf Zeisler
The National Institute of Standards and Technology (NIST, Gaithersburg, MD) issued a new series of Standard Reference Materials® (SRMs) targeting the ever-increasing list of potentially toxic ... Read More
A Novel Approach to Particle Size Measurement in the Single-Nanometer Range
Saturday, August 01, 2009
Yanyin Yang Robert H. Clifford Gilbert Vial Haruo Shimaoka
Nanotechnology is pervasive, as evidenced by the abundance of information found in the latest scientific journals. What is nanotechnology? According to the National Nanotechnology Initiative, “a ... Read More