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Title
Automating Sample Preparation in the Metals Laboratory
Saturday, August 01, 2009
Joe Boyd
Preparing samples for analysis is an extremely time-consuming task. In fact, sample preparation steps can easily take up more time in the laboratory than the actual analysis. With autosamplers on ...
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A Nondestructive Technique for the Detection of Metallic Impurities in Alloys
Tuesday, September 01, 2009
John R. Dannecker
Neil D. Fichtelberg
Scott A. Knowles
Examples of welds contaminated with small quantities of incorrect weld filler metal were recently discovered in fabricated assemblies. The presence of such impurities, which are not detectable using ...
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1-mm-i.d. Monolithic HPLC Columns for High-Efficiency Protein Separations
Tuesday, September 01, 2009
Sebastiaan Eeltink
Remco Swart
The preparation of monolithic separation media for HPLC composed of a single, continuous polymer macroporous support has been reported since the late 1960s. Due to its unique material properties, ...
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Knowledge Management and Efficiency Gains
Tuesday, September 01, 2009
Paul Denny-Gouldson
Eliot Randle
In the face of escalating R&D costs, currently estimated at $800 million U.S. to produce a new drug, the life science discovery industry is constantly searching for ways to control expenditure, ...
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Quality Checking for High-Throughput Screening
Friday, September 25, 2009
Jan Wagner
Matthias Gierth
Marc Bickle
Chemical screening requires methods for the liquid handling of chemical compounds.
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Quality Checking for High-Throughput Screening
Friday, September 25, 2009
Jan Wagner
Matthias Gierth
Marc Bickle
Chemical screening requires methods for the liquid handling of chemical compounds.
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Dietary Supplement Standard Reference Materials
Thursday, October 01, 2009
Lane C. Sander
Karen W. Phinney
Michele M. Schantz
Katherine E. Sharples
Stephen A. Wise
In 1994, the U.S. Congress enacted the Dietary Supplement Health and Education Act (DSHEA) to "protect the right of access of consumers to safe dietary supplements." One way in which this is expected ...
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Reduced Carryover Using an LC Autosampler System
Thursday, October 01, 2009
Osamu Shirota
Kazuhiko Mibayashi
Yasutaka Naruse
Masashi Mita
Recent high-sensitivity and high-throughput trends in liquid chromatography,influenced largely by the latest interfacing technologies of mass spectrometry, seem to demand further improvements in ...
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Impurity Evaluation of Heparin Sodium by Anion Exchange Chromatography
Thursday, October 01, 2009
Catalin E. Doneanu
Weibin Chen
As a blood-thinning drug, heparin and its derivative, low-molecular-weight heparin (LMWH), have been widely used for decades during surgery and kidney dialysis.
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Plate Washing in 1536: Evaluation of a Double-Column Aspirator Head
Thursday, October 22, 2009
Michelle Batchlett
Jason Cassaday
Carissa Ohart
Kurtis Berry
Oleg Kornienko
Jim Chang
Plate assays (1536-well) that require washing (i.e., enzyme-linked immunosorbent assays [ELISAs] and cell-based), are not routinely implemented in high-throughput screening laboratories due to the ...
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TIRF Microscopy Software for Automated Vesicle Fusion Detection
Thursday, October 22, 2009
Katarina Mele
James G. Burchfield
Jamie Lopez
David E. James
William E. Hughes
Adelle Coster
Pascal Vallotton
The recent explosion in the use of total internal reflection fluorescence (TIRF) microscopy to learn about cell trafficking means that there is an urgent need for software capable of annotating the ...
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Professional LIMS Delivered On-Demand
Friday, October 30, 2009
Thomas Kent
Steven Chen
Scientific laboratories are at the heart of most breakthroughs, investigative discoveries, and product development efforts in science-related operations.
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Fluorescence Microscopy: Solving Common Documentation Challenges
Sunday, November 01, 2009
Mark Clymer
Fluorescence has proven to be a useful technique for identifying, tracking, and studying molecules of interest in biological specimens. In fact, fluorescence is among the fastest growing microscopy ...
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Use of an Automated Microscope Platform for Protein and Small-Molecule Crystal Harvesting
Sunday, November 01, 2009
Tom Friedlander
A standard laboratory microscope is a necessary tool in almost every laboratory in the world. While electron, fluorescence, confocal, and atomic force microscopes (AFMs) are gaining in popularity, the...
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Advances in Cryo-SEM: From Micrometers to Nanometers
Sunday, November 01, 2009
Jens Greiser
Science is driving the demand for nanoscale resolution. Cryo-scanning electron microscopy (cryo-SEM), which combines the high-performance imaging of scanning electron microscopy (SEM) with cryogenic ...
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The Helium Ion Microscope: Advances in Technology and Applications
Sunday, November 01, 2009
Larry Scipioni
Paul Alkemade
Vadim Sidorkin
Ping Chen
Diederik Maas
Emile van Veldhoven
Helium ion microscopy (HIM) offers the highest spatial resolution surface imaging of any scanning beam method, as well as extremely high surface sensitivity.
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An Automated Surface Plasmon Resonance-Based System
Tuesday, December 01, 2009
John Quinn
Aaron Martin
Nathan Gillock
Jeffery Havard
Over the past 15 years, label-free, real-time biomolecular interaction analysis has established itself across a broad spectrum of disciplines from drug discovery to basic life science R&D.
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A Research Tool for Sample Preparation and Microfluidics
Tuesday, December 01, 2009
Jason Tucker
Shane Woody
Precision ultrasonic microvortexing is an underexplored area in biophysics research, a pathway to automation for portable lab-on-a-chip (LOC) systems, biodetection, assays, and screening.
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Use of High-Content Tools to Drive Innovation and Collaboration in the Biotechnology Industry
Tuesday, December 01, 2009
Joe Zock
The biotechnology industry has been hit hard by the current financial crisis and faces a future where efficiency and collaboration will be prerequisites for survival.
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Confidence Up Close
Friday, January 01, 2010
Aubrey Lambert
The combined pressures of continuing miniaturization, higher packing densities, and rigorous quality assurance means that the physical size of particles capable of adversely affecting industrial ...
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