Application Notes

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The Spirit of Creation: Milestones in Microscopy
Friday, September 28, 2018
Takeo Ogama
Instruments developed in Olympus’ nearly 100-year history encompass research, the clinical laboratory, and the life sciences. Read More
The Significance of pH Stability for Cell Cultures
Thursday, September 01, 2005
Daniela Maurer
Cell culture media generally comprise amino acids, salts, vitamins, other substances, and an anorganic buffer substance (NaHCO3). Read More
The Science of a Lab Relocation
Thursday, June 20, 2019
George Rohlfing
Key points to ensure a successful lab relocation. Read More
The Scales of Scientific Justice in Translational Science: Data Reproducibility and Verifiable Science
Tuesday, March 04, 2014
Tristan Berto
The traditional “scales of justice” represent truth and fairness. For the scientific community, the balance is between big data (terabytes of data across numerous databases) on one scale and ... Read More
The Road to Improved Next-Generation Sequencing Through Innovative PCR Instrumentation
Friday, November 20, 2015
Andrew Birnie
Next-generation sequencing (NGS), one of the most significant technological advances in the the last 30 years, allows millions of DNA strands to be sequenced in parallel. Read More
The Power of Pulsed Amperometric Detection Coupled With Chromatography for Analyzing Carbohydrates
Saturday, October 01, 2011
George Limpert
Most chemists vaguely remember a portion of their instrumental analysis course that covered electroanalytical chemistry. Read More
The Power of Modern Super-Resolution Microscopy
Tuesday, June 05, 2018
Lauren Alvarenga
As technology advances and software becomes more sophisticated, optical and computational super-resolution techniques are coming together in commercial imaging instruments to offer flexible, ... Read More
The Personal Proteome: What It Can Tell Us and How Current Advances in Technology Could Make the Proteome an Everyday Measurement
Tuesday, August 07, 2018
Jeff Jones Ryan Benz
The personal proteome has real potential to become a daily assessment tool that could benefit individuals needing to track disease progression or recovery outcome. Read More
The Performance Capability of a Fully Automated Concentrator System as Compared to the Traditional Kuderna Danish Method
Saturday, January 01, 2005
Robert Johnson
Environmental samples, including water and soils,extracted with an organic solvent must typically be dried and concentrated before analysis. Read More
The Path to the Paperless Laboratory: A Workstation-Based Consumables Inventory Management System
Tuesday, June 01, 2010
John P. Helfrich
In all analytical laboratories, the purchase, preparation, storage, and control of chemical reagents, standards, and working reagents are routine tasks. Read More
The Myths and Truths of Measuring Pure Water
Monday, November 07, 2016
Gayle Gleichauf Kim Knepper
Techniques such as liquid chromatography and mass spectrometry require ultrapure water (UPW) for trace-level analysis. Read More
The Multidisciplinary Electronic Laboratory Notebook: Pipe Dream or Proven Success?
Tuesday, November 01, 2011
Dominic John Mariusz Banaszczyk Gabriel Weatherhead
Electronic laboratory notebooks (ELNs) emerged in the R&D landscape around 15 years ago with a commendable objective: reduce or eliminate the errors and inefficiencies driven by the use of paper ... Read More
The Missing Link Between HPLC and UPLC Technology
Monday, February 01, 2010
William Foley Beth Gildea Thomas E. Wheat
Having proven its performance and reliability under extremely rigorous conditions for the most demanding applications, UPLC technology has brought routine benefits to increasing numbers of scientists,... Read More
The Importance of Monodisperse Silica in the Evolution of UHPLC and HPLC Column Performance
Tuesday, March 10, 2015
Richard A. Henry Paul Ross William R. Betz Gaurang Parmar Wayne K. Way
There is growing interest in the use of monodisperse particle-size distribution or PSD (here defined as having 10% RSD or less) to prepare modern HPLC columns because good correlation has been ... Read More
The Importance of Controlled Concentration and Drying in MALDI-TOF Applications
Friday, July 01, 2005
Steve Knight
Matrix-assisted laser desorption/ionization-time- of-flight mass spectrometry (MALDI-TOF MS) is now an accepted and routine analysis technique for the elucidation and quantitation of biomolecules ... Read More
The Impact of Chiral Supercritical Fluid Chromatography in Drug Discovery: From Analytical to Multigram Scale
Thursday, June 01, 2006
Dauh-Rurng Wu Leslie Leith Balu Balasubramanian Todd Palcic David Wang-Iverson
A significant responsibility for the analytical group within Drug Discovery Chemistry at Bristol Myers-Squibb (Princeton, NJ) is the chromatographic purification of chiral compounds, both ... Read More
The Hollow Fiber Bioreactor and Cell Co-Cultivation
Tuesday, June 12, 2012
John J.S. Cadwell
Historically, the scientific method had been based upon the reduction of complex systems to their simplest forms in order to understand their individual processes. Read More
The Helium Ion Microscope: Advances in Technology and Applications
Sunday, November 01, 2009
Larry Scipioni Paul Alkemade Vadim Sidorkin Ping Chen Diederik Maas Emile van Veldhoven
Helium ion microscopy (HIM) offers the highest spatial resolution surface imaging of any scanning beam method, as well as extremely high surface sensitivity. Read More
The Future of Rapid On-Line Measurement
Monday, February 01, 2010
Aubrey Lambert
Fiber optic technology has already radically altered the telecommunications field, by carrying highly multiplexed data at great speeds over vast distances. Now these capabilities have been packaged ... Read More
The Future of Information Technology: Selecting a Forward- Looking LIMS Vendor
Friday, March 10, 2006
David Leitham
Most sophisticated LIMS purchasers have a well-developed methodology for evaluating which system best meets their needs. Read More

Sort

The Spirit of Creation: Milestones in Microscopy

The Significance of pH Stability for Cell Cultures

The Science of a Lab Relocation

The Scales of Scientific Justice in Translational Science: Data Reproducibility and Verifiable Science

The Road to Improved Next-Generation Sequencing Through Innovative PCR Instrumentation

The Power of Pulsed Amperometric Detection Coupled With Chromatography for Analyzing Carbohydrates

The Power of Modern Super-Resolution Microscopy

The Personal Proteome: What It Can Tell Us and How Current Advances in Technology Could Make the Proteome an Everyday Measurement

The Performance Capability of a Fully Automated Concentrator System as Compared to the Traditional Kuderna Danish Method

The Path to the Paperless Laboratory: A Workstation-Based Consumables Inventory Management System

The Myths and Truths of Measuring Pure Water

The Multidisciplinary Electronic Laboratory Notebook: Pipe Dream or Proven Success?

The Missing Link Between HPLC and UPLC Technology

The Importance of Monodisperse Silica in the Evolution of UHPLC and HPLC Column Performance

The Importance of Controlled Concentration and Drying in MALDI-TOF Applications

The Impact of Chiral Supercritical Fluid Chromatography in Drug Discovery: From Analytical to Multigram Scale

The Hollow Fiber Bioreactor and Cell Co-Cultivation

The Helium Ion Microscope: Advances in Technology and Applications

The Future of Rapid On-Line Measurement

The Future of Information Technology: Selecting a Forward- Looking LIMS Vendor

Product Guide

Micromachined HPLC Columns Can Revolutionize Proteomics Workflows

Buyer's Guide: GC-MS for Monitoring Environmental Pollutants

Refocusing the Lens of Cancer Screening

Study: NGS Should Be Go-to Technology on Day Zero of the Next Pandemic

Overcoming Common Challenges in Sample Viability for Single-Cell Research