Application Notes

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Use of Microcalorimetry to Study Protein Stability
Monday, February 16, 2015
Rémi André Link Brown
Differential scanning calorimetry (DSC) is used in the pharmaceutical, polymer and biotechnology industries to study the effect of temperature on a variety of solids or liquids, including those that ... Read More
Use of LIMS to Improve Trace Evidence Management in the Crime Laboratory
Monday, August 27, 2012
Robin Gall
Police do not get a second chance to collect evidence at a chaotic crime scene. Read More
Use of High-Resolution MS for Discovery Pharmocokinetics and Simultaneous Analysis of Metabolites
Tuesday, February 01, 2011
Rohan A. Thakur Mike Koleto
It is essential to eliminate poor drug candidates as early as possible in the drug development process. Unfavorable pharmacokinetic (PK) properties have frequently been the reason for failure of new ... Read More
Use of High-Content Tools to Drive Innovation and Collaboration in the Biotechnology Industry
Tuesday, December 01, 2009
Joe Zock
The biotechnology industry has been hit hard by the current financial crisis and faces a future where efficiency and collaboration will be prerequisites for survival. Read More
Use of Heat Stabilization to Preserve Lipids and Improve Sample Quality
Friday, June 12, 2015
Marcus Söderquist
Lipids have long been considered to be mere building blocks of cell membranes or energy-storage molecules. It is now evident, however, that these small, nonpolymeric molecules play several key roles ... Read More
Use of Environmental Transmission Electron Microscopy to Study the Dynamic, Catalytic Reactions on Metal Nanoparticle Catalysts
Thursday, October 16, 2014
Joerg Jinschek
Prof. Seiji Takeda leads a research group in the Department of Nanocharacterization for Nanostructures and Functions of the Nanoscience and Nanotechnology Center at the Institute of Scientific and ... Read More
Use of an FTIR Spectrometer to Characterize the Spectral Output of a Near-Infrared Diode Laser
Thursday, September 01, 2011
Richard Spragg
Characterizing the spectral output of a diode laser requires more than simply measuring the center wavelength with a wavemeter. Read More
Use of an Environmental Transmission Electron Microscope for Dynamic in situ Studies of Nano-Structured Materials at the Atomic Scale
Thursday, March 07, 2013
Joerg R. Jinschek
Current research and development (R&D) that is focused on efficient energy conversion and environmental protection technologies relies heavily on advances in the development of new and improved ... Read More
Use of an Automated Microscope Platform for Protein and Small-Molecule Crystal Harvesting
Sunday, November 01, 2009
Tom Friedlander
A standard laboratory microscope is a necessary tool in almost every laboratory in the world. While electron, fluorescence, confocal, and atomic force microscopes (AFMs) are gaining in popularity, the... Read More
Use of a Planetary Ball Mill for Cryogenic Grinding of Yeast Cells
Thursday, September 20, 2012
Kyle James
The Michael Rout Lab at the Rockefeller University in New York, NY, initially contacted Retsch Inc. (Newtown, PA) in 2006 to discuss the possibility of using the Planetary Ball Mill to cryogenically... Read More
Use of a Pen-Shaped Capillary Gel Electrophoresis Cartridge for Cost-Effective DNA Fragment Analysis
Tuesday, July 31, 2012
Varouj Amirkhanian Eric Tsai
Most laboratories currently utilize slab-gel electrophoresis systems for DNA and protein analysis. However, both polyacrylamide gel electrophoresis (PAGE) and agarose slab-gel electrophoresis ... Read More
Use of a LIMS to Help Manage a Larger Workload With Reduced Staff
Wednesday, November 01, 2006
Carolyn Vaughn
A leading manufacturer of tablets, softgels, and two-piece hard-shells in the nutraceuticals and personal health enhancement market, like other players in the industry, faced the challenge of meeting... Read More
Urinary Drug Testing: Small Changes for Big Improvements in Sensitivity
Tuesday, September 27, 2016
Jenny Cybulski
An oversight or mistake in drug testing can have dire consequences—a positive drug test can ruin the possibility of employment, turn an accident into a lawsuit, or cause a physician to discontinue ... Read More
Understanding the Potential of Near-Infrared Chemical Imaging
Monday, October 27, 2008
Janie Dubois Neil Lewis
Improvements in the price–performance ratio of digital imaging cameras coupled with better data processing tools have promoted the use of “machine vision.” Read More
Understanding Concentration and Evaporation and Technology: Part 1: Basic Principles of Commonly Used Evaporation Techniques
Wednesday, February 06, 2013
Induka Abeysena Rob Darrington
Solvent removal is an essential process across a broad range of applications in the pharmaceutical, chemical, and biotechnology industries. Although a diversity of sample formats and solvents are used... Read More
Understanding Concentration and Evaporation Technology: Part 2: Latest Developments in System Technology
Tuesday, February 26, 2013
Induka Abeysena Rob Darrington
An understanding of the evaporative process and factors affecting it, involving careful selection of a vacuum pump, cold trap or condenser, and consideration of pressure control, is key to obtaining a... Read More
Ultrasensitive Calorimetry: One of the Best-Kept R&D Secrets
Monday, October 01, 2007
Ed Sullivan
The first calorimetric test most of us performed was probably either the classic Styrofoam cup test or the more sophisticated bomb (combustion chamber) calorimeter, which allowed the measurement of ... Read More
Ultrasensitive 3D Confocal Raman Imaging
Monday, January 27, 2014

This article describes integration of a Raman spectrometer and a state-of-the-art confocal microscope to achieve ultrafast Raman imaging. The alpha300 R ultrafast confocal Raman imaging system was ... Read More
Ultrafast Confocal Raman Imaging - Application Examples
Monday, January 27, 2014

Using the Ultrafast Confocal Raman Imaging Option, a single Raman spectrum can be acquired in as few as 760 µsec. A wide variety of samples can be analyzed with the Ultrafast Confocal Raman Imaging ... Read More
UCMR4, Microcystins Analysis, and High-Resolution Mass Spectrometry for Confidence in Identity Confirmation
Monday, March 26, 2018
Craig Butt April Quinn-Paquet K.C. Hyland
Quantitation of a suite of microcystins and nodularin was demonstrated using LC-MS/MS on a QTOF system. Read More

Sort

Use of Microcalorimetry to Study Protein Stability

Use of LIMS to Improve Trace Evidence Management in the Crime Laboratory

Use of High-Resolution MS for Discovery Pharmocokinetics and Simultaneous Analysis of Metabolites

Use of High-Content Tools to Drive Innovation and Collaboration in the Biotechnology Industry

Use of Heat Stabilization to Preserve Lipids and Improve Sample Quality

Use of Environmental Transmission Electron Microscopy to Study the Dynamic, Catalytic Reactions on Metal Nanoparticle Catalysts

Use of an FTIR Spectrometer to Characterize the Spectral Output of a Near-Infrared Diode Laser

Use of an Environmental Transmission Electron Microscope for Dynamic in situ Studies of Nano-Structured Materials at the Atomic Scale

Use of an Automated Microscope Platform for Protein and Small-Molecule Crystal Harvesting

Use of a Planetary Ball Mill for Cryogenic Grinding of Yeast Cells

Use of a Pen-Shaped Capillary Gel Electrophoresis Cartridge for Cost-Effective DNA Fragment Analysis

Use of a LIMS to Help Manage a Larger Workload With Reduced Staff

Urinary Drug Testing: Small Changes for Big Improvements in Sensitivity

Understanding the Potential of Near-Infrared Chemical Imaging

Understanding Concentration and Evaporation and Technology: Part 1: Basic Principles of Commonly Used Evaporation Techniques

Understanding Concentration and Evaporation Technology: Part 2: Latest Developments in System Technology

Ultrasensitive Calorimetry: One of the Best-Kept R&D Secrets

Ultrasensitive 3D Confocal Raman Imaging

Ultrafast Confocal Raman Imaging - Application Examples

UCMR4, Microcystins Analysis, and High-Resolution Mass Spectrometry for Confidence in Identity Confirmation

Product Guide

Micromachined HPLC Columns Can Revolutionize Proteomics Workflows

Buyer's Guide: GC-MS for Monitoring Environmental Pollutants

Refocusing the Lens of Cancer Screening

Study: NGS Should Be Go-to Technology on Day Zero of the Next Pandemic

Overcoming Common Challenges in Sample Viability for Single-Cell Research