Application Notes

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Use of High-Content Tools to Drive Innovation and Collaboration in the Biotechnology Industry
Tuesday, December 01, 2009
Joe Zock
The biotechnology industry has been hit hard by the current financial crisis and faces a future where efficiency and collaboration will be prerequisites for survival. Read More
Use of High-Resolution MS for Discovery Pharmocokinetics and Simultaneous Analysis of Metabolites
Tuesday, February 01, 2011
Rohan A. Thakur Mike Koleto
It is essential to eliminate poor drug candidates as early as possible in the drug development process. Unfavorable pharmacokinetic (PK) properties have frequently been the reason for failure of new ... Read More
Use of LIMS to Improve Trace Evidence Management in the Crime Laboratory
Monday, August 27, 2012
Robin Gall
Police do not get a second chance to collect evidence at a chaotic crime scene. Read More
Use of Microcalorimetry to Study Protein Stability
Monday, February 16, 2015
Rémi André Link Brown
Differential scanning calorimetry (DSC) is used in the pharmaceutical, polymer and biotechnology industries to study the effect of temperature on a variety of solids or liquids, including those that ... Read More
Use of New Scanning Technology to Elucidate Ion Channel Mobility
Friday, April 01, 2005
Angela Goodacre Kristen M.S. O’Connell Michael M. Tamkun
Fluorescent chromophores fused to specific proteins have greatly increased our ability to image dynamic events within the living cell. Read More
Use of Odor Detection Software to Match GC-MS Library Search Results and Odor-Active Compounds
Tuesday, June 01, 2010
Philippe Mottay Robert Stoop Peter Picher Urs Hofstetter
Because GC and GC-MS are not always sufficient for olfactory analysis, chemists turn to gas chromatography– olfactometry (GC-O) for the detection of low-level odor-active compounds. Though powerful... Read More
Use of Rotational Vane Rheometry to Solve Practical Problems
Saturday, August 01, 2009
David J. Moonay
Rheology is the study of the deformation of matter. A common definition is that rheology is the study of flow. Viscometry, in particular, is the measurement of viscosity or the resistance to flow. ... Read More
Use of SEC–MALS–dRI–UV for Copolymer Characterization
Tuesday, June 12, 2018

Conventional techniques used to characterize polymers, such as NMR and size-exclusion chromatography/differential refractive index detection, are often labor intensive, complex to perform, and high in... Read More
Use of UHPLC-MS to Determine Illicit Drugs
Sunday, August 01, 2010
Guifeng Jiang
Illicit drugs are listed under five categories,namely, narcotics, stimulants, depressants, hallucinogens, and cannabis. These categories include drugs that are produced legally and prescribed by ... Read More
Use of Weighted Least Squares and Confidence Band Calibration Statistics to Find Reliable Instrument Detection Limits for Trace Organic Chemical Analysis
Friday, September 11, 2015
Paul R. Loconto
Instrument detection limits (IDLs or xD) obtained from applying either ordinary least squares/confidence band calibration statistics (OLS/CBCS) or weighted least squares/confidence band calibration ... Read More
$Use of X-ray Diffraction Analysis to Determine the Orientation of Single-Crystal Materials$
Use of X-ray Diffraction Analysis to Determine the Orientation of Single-Crystal Materials
Friday, April 08, 2011
Ronald Kappler Dave Lydon Ted Turnquist
Single crystals exhibit different properties, depending on the material and their orientation. Read More
Using a Purge-and-Trap Concentrator for Newly Proposed U.S. EPA Method 524.3
Thursday, June 18, 2009
Teri Dattilio
Purge-and-trap (P&T) concentration along with GC analysis is a widely used method for the detection of volatile organic compounds (VOCs). This methodology was developed to achieve the high sensitivity... Read More
Using Advanced Airflow Controls to Ensure Safe Air in the Laboratory
Thursday, September 20, 2018
Dave Rausch
While thousands of laboratories around the world continue to use traditional airflow controls, for enhanced safety and energy savings and reduced valve maintenance, venturi valves offer a higher-... Read More
Using Advanced Data-Management Solutions to Ensure Food Safety
Monday, May 08, 2017
Jeff Tishler Kevin Arnold
Accurate recording of research data and the ability to quickly search historical data and track the genealogy of products result in products being developed more rapidly and consistently while ... Read More
Using Benchtop NMR as a QA Solution in Food and Agriculture
Tuesday, April 10, 2012
Juergen Schober Jim Vecchio John Paul Cerroti
The measurement of parameters such as oil, fat, and moisture content is important to help define the nutritional value and product quality for many foodstuffs and agriculture products. Read More
Using Classifications With Mass Spectral Filters to Enhance Results Obtained From GC×GC-TOFMS Analysis
Wednesday, February 01, 2006
Tincuta Veriotti Don Hilton
Complex sample mixtures have always been a challenge for the analytical chemist. Read More
Using Dynamic Light Scattering to Improve Protein Solution Behavior for Crystallization
Friday, June 01, 2007
Allan Matte Miroslaw Cygler
Improving protein solution behavior is critical in the field of structural biology since it impacts protein crystallization and the ability to determine protein structures by solution nuclear ... Read More
Using Freshly Delivered Ultrapure Water With Low TOC Improves Chromatographic Performance
Wednesday, January 27, 2016
Stéphane Mabic Estelle Riche Cecilia Devaux
Analytical instruments have become increasingly sensitive, requiring a higher level of reagent and solvent quality, including water. Read More
Using Micro-XRF to Quantify Thickness and Composition of Thin-Film Solar Cells
Wednesday, February 05, 2014
Andrew Lee
Thin-film solar cells (TFSCs) have developed into a highly efficient source of energy in solar cell technology, due to the reduction in semiconductor material required compared to traditional solar ... Read More
Using Raman Spectroscopy for Gemstone Analysis
Wednesday, June 07, 2017
Frank J. Yang Gerard Pereira Liang Don Chen
Raman spectroscopy is a nondestructive, extremely fast and low-cost option for gemstone analysis. Read More

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Use of High-Content Tools to Drive Innovation and Collaboration in the Biotechnology Industry

Use of High-Resolution MS for Discovery Pharmocokinetics and Simultaneous Analysis of Metabolites

Use of LIMS to Improve Trace Evidence Management in the Crime Laboratory

Use of Microcalorimetry to Study Protein Stability

Use of New Scanning Technology to Elucidate Ion Channel Mobility

Use of Odor Detection Software to Match GC-MS Library Search Results and Odor-Active Compounds

Use of Rotational Vane Rheometry to Solve Practical Problems

Use of SEC–MALS–dRI–UV for Copolymer Characterization

Use of UHPLC-MS to Determine Illicit Drugs

Use of Weighted Least Squares and Confidence Band Calibration Statistics to Find Reliable Instrument Detection Limits for Trace Organic Chemical Analysis

Use of X-ray Diffraction Analysis to Determine the Orientation of Single-Crystal Materials

Using a Purge-and-Trap Concentrator for Newly Proposed U.S. EPA Method 524.3

Using Advanced Airflow Controls to Ensure Safe Air in the Laboratory

Using Advanced Data-Management Solutions to Ensure Food Safety

Using Benchtop NMR as a QA Solution in Food and Agriculture

Using Classifications With Mass Spectral Filters to Enhance Results Obtained From GC×GC-TOFMS Analysis

Using Dynamic Light Scattering to Improve Protein Solution Behavior for Crystallization

Using Freshly Delivered Ultrapure Water With Low TOC Improves Chromatographic Performance

Using Micro-XRF to Quantify Thickness and Composition of Thin-Film Solar Cells

Using Raman Spectroscopy for Gemstone Analysis

Product Guide

Micromachined HPLC Columns Can Revolutionize Proteomics Workflows

Buyer's Guide: GC-MS for Monitoring Environmental Pollutants

Refocusing the Lens of Cancer Screening

Study: NGS Should Be Go-to Technology on Day Zero of the Next Pandemic

Overcoming Common Challenges in Sample Viability for Single-Cell Research