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UCMR4, Microcystins Analysis, and High-Resolution Mass Spectrometry for Confidence in Identity Confirmation
Monday, March 26, 2018
Craig Butt
April Quinn-Paquet
K.C. Hyland
Quantitation of a suite of microcystins and nodularin was demonstrated using LC-MS/MS on a QTOF system.
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Centrifugal Partition Chromatography: The Key to Green Preparative Chromatography
Monday, March 26, 2018
Gregoire Audo
Centrifugal partition chromatography is a sustainable solution for reducing the environmental impact of preparative chromatography while reducing production costs.
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Minimizing Contamination in Cell Culture Laboratories
Tuesday, March 27, 2018
Mary Kay Bates
Cell culture laboratories share the requirement for equipment and consumables that help to reduce contamination, protecting sample integrity for downstream use.
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On-Scene HAZMAT Response and Chemical Confirmation With GC/MS
Tuesday, March 27, 2018
Philip Tackett
Two situations are presented in which a person-portable GC/MS can be used to provide confirmatory chemical identification.
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Effects of Sodium Silicate on Self-Degradable Cementitious Composites
Wednesday, March 28, 2018
Xiuhua Zheng
Shiwei Yang
Zhongli Lei
Huijing Tan
Bairu Xia
Sodium silicate plays an important role in the hydration and self-degradation of geothermal temporary sealing materials, prepared by introducing sodium carboxymethyl cellulose (CMC) into sodium ...
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Statistics in the Laboratory: Mandel Sensitivity
Wednesday, March 28, 2018
Stanley N. Deming
In the three previous columns, we discussed the limit of detection amount LDA, the minimum consistently detectable amount MCDA, and the limit of quantitation amount LQA.
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Reducing the Total Cost of Biological Safety Cabinet Ownership
Tuesday, May 01, 2018
Martin Cole
Minimizing the total cost of BSC ownership can help lab managers realize their sustainability goals through energy savings and reduced heat emissions.
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Routine Maintenance in ICP-MS: Critical When Monitoring Elemental Impurities in Pharmaceuticals
Tuesday, May 01, 2018
Robert Thomas
Routine maintenance is critical in ICP-MS, and this article provides guidance on keeping the sample introduction clean.
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Improving Protein Purification Efficiency of Biologics
Tuesday, May 01, 2018
Candice Cox
Multi-D chromatography reduces time to results and increases the robustness and reproducibility of small-batch biologic purification.
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High-Throughput Capillary Electrophoresis: The Key to Streamlined Quality Analysis for Next-Gen Sequencing
Tuesday, May 01, 2018
Steve Siembieda
The introduction of automated, high-throughput capillary electrophoresis instruments has made it possible to streamline the analysis of next-generation sequencing libraries.
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Strategies for Deep Imaging With Multiphoton Microscopy
Wednesday, May 02, 2018
Carlo Amadeo C. Alonzo
Multiphoton microscopy can inform strategies for maximizing depth penetration through highly scattering specimens.
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Extending the Limits: Oil Immersion Flow Microscopy
Thursday, May 03, 2018
Chris Sieracki
An imaging flow microscope with properly configured oil immersion optics can be used to analyze samples with particles down to about 300 nanometers.
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Optical Efficiency Effects on Infrared Diffuse Reflection Spectroscopy Signal-to-Noise Ratio
Thursday, May 03, 2018
Dalia K. Maraoulaite
Robert L. White
This paper describes the impact of typical DRIFTS optical configurations on measurement SNR.
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How Visualization and Analytics Help Scientists Make Better Decisions Faster
Friday, May 11, 2018
Tom Oldfield
Robert D. Brown
Artificial intelligence. Machine learning. Automation. As these technologies become more widely adopted among life sciences companies in hopes of better innovation and faster drug development, it is ...
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The Power of Modern Super-Resolution Microscopy
Tuesday, June 05, 2018
Lauren Alvarenga
As technology advances and software becomes more sophisticated, optical and computational super-resolution techniques are coming together in commercial imaging instruments to offer flexible, ...
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Enabling Verifiable Science Through Smart, Connected Lab Devices
Tuesday, June 05, 2018
Tiphaine De Jouvencel
IoT laboratory devices such as cloud-enabled pipettes and electronic lab notebooks improve reproducibility.
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Investigating Membrane Proteins Using Native Mass Spectrometry
Tuesday, June 05, 2018
Kelly Broster
A new application of native mass spectroscopy analyzes membrane proteins for the first time.
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A Simple Way to Reduce Analysis Time in GC
Tuesday, June 05, 2018
Jaap de Zeeuw
An easy tool can be used to decrease analysis times in GC.
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Use of SEC–MALS–dRI–UV for Copolymer Characterization
Tuesday, June 12, 2018
Conventional techniques used to characterize polymers, such as NMR and size-exclusion chromatography/differential refractive index detection, are often labor intensive, complex to perform, and high in...
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A Flexible Measurement System for Online Reaction Monitoring Using ESI-MS and ICP-MS
Tuesday, August 07, 2018
Heidi Fleischer
Kerstin Thurow
Vinh Quang Do
An online reaction monitoring system can be coupled to several measurement instruments using an electrospray ionization mass spectrometer (ESI-MS) to receive structural information and an inductively ...
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