Application Notes

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Spectroscopic Ellipsometry Characterization of Thin Films Used in the Food Packaging Industry
Tuesday, June 11, 2013
Michelle N. Sestak
Process control and optimization is critical for low-cost, high-throughput, thin-film applications, such as barrier layers used in the food packaging industry. One useful technique for determining ... Read More
Handheld and Portable FTIR Spectrometers for the Analysis of Materials: Taking the Lab to the Sample
Friday, June 07, 2013
Alan J. Rein John Seelenbinder
Industrial and academic scientists working in the development and application of engineered materials are increasingly in need of measurement technologies that can be used closer to the source of the... Read More
Fast, Efficient Antibody Biotinylation for Cleaner Immunodetection Assays
Friday, June 07, 2013
Amedeo Cappione Masaharu Mabuchi David Briggs Timothy Nadler
Many protein detection methods, including Western blotting, flow cytometry, ELISA, and immunohistochemistry, require the use of target-specific probes, such as antibodies, that are detected via two-... Read More
Development of a 100% Dimethyl Sulfoxide (DMSO) Sample Solution for Liquid Handler Performance Verification
Friday, June 07, 2013
Rachel Parshley John Thomas Bradshaw Karl Olson
Dimethyl sulfoxide (DMSO) has become one of the most important solvents used for high-throughput screening (HTS) and compound management applications due to its ability to readily dissolve a wide ... Read More
A Novel Sample Preparation Method for Complete Digestion of Complex Pharmaceutical Matrices
Friday, June 07, 2013
Reynhardt Klopper Eric Fox
For more than 100 years, the USP General Chapter <231> concomitant visual test was the standard method for the determination and quantification of heavy metal impurities present in pharmaceutical products ... Read More
How to Select the Best siRNA Transfection Reagent
Wednesday, June 05, 2013
Josh P. Roberts
The choice of a transfection reagent for small, interfering RNAs, or siRNAs, is largely dependent on the type of cell and species and the downstream assay. According to this guide, the two most ... Read More
Choosing Conservation Over Conversion: The Great Helium Debate
Thursday, May 23, 2013
Frank Kandl Reginald Bartram
In recent months, the growing shortage of helium has gained national attention and raised concerns of availability and cost among users. Laboratories in particular rely on helium for analytical ... Read More
The Streck HbA1c-Cellular® Control: Intact Red Blood Cells for Hemoglobin A1c Testing
Thursday, May 23, 2013

Glycated hemoglobin A, or HbA1c, testing is the most effective means of monitoring diabetes mellitus and determining how well the disease is being controlled. HbA1c testing can now be used to diagnose... Read More
Point-of-Care Tests for Anemia
Wednesday, May 22, 2013

The presence of anemia, which is the insufficient oxygen-carrying capacity of the blood, can be determined by the total hemoglobin concentration. This lab test is the most commonly ordered in hospital... Read More
Detection of siRNA-Mediated Gene Modulation Using RNA Detection Probes
Monday, May 20, 2013
Don Weldon Grace Johnston
To study the function of genes and biological pathways, researchers often use techniques such as RNA interference (RNAi) to modify gene expression. In RNAi experiments, it is important to determine ... Read More
Working Flow Rate: How to Compare Vacuum Pumps
Friday, May 17, 2013
Peter Coffey
To compare vacuum pumps, it is imperative to look at the pumping speed at working vacuum levels. The working vacuum level is the vacuum at which you need to operate your application. Comparing the ... Read More
Measurement and Prediction of Fluid Viscosity at High Shear Rates
Tuesday, April 09, 2013
Tien T. Dao Jeshwanth K. Rameshwaram
Polymeric materials, in a general sense, are viscoelastic in nature since they exhibit a strong dependence of deformation and flow on time and temperature. Performance of these materials can only be ... Read More
Automated Cell Staining in Drug Discovery
Tuesday, April 09, 2013
Amy Yoder Li Liu
Cell and molecular biology become more integral pieces of the modern drug discovery process on a seemingly daily basis. Monitoring the interaction of cells and internal cellular activity provides ... Read More
Automation in the Drug Discovery Process: Delivering Analytical Chemistry to Biologists and Beyond
Friday, March 08, 2013
Wendy Gaisford
Over the past decade, advances in genomic- and proteomic-based research techniques and instrumentation have resulted in major breakthroughs in the elucidation of the structure and function of disease ... Read More
Differential Scanning Calorimetry (DSC) as an Analytical Tool in Plastics Failure Analysis
Thursday, March 07, 2013
Kadine Mohomed David A. Bohnsack
Thermal analysis includes techniques in which a physical property of a substance is measured as a function of temperature and time while the substance is subjected to a controlled temperature program... Read More
Use of an Environmental Transmission Electron Microscope for Dynamic in situ Studies of Nano-Structured Materials at the Atomic Scale
Thursday, March 07, 2013
Joerg R. Jinschek
Current research and development (R&D) that is focused on efficient energy conversion and environmental protection technologies relies heavily on advances in the development of new and improved ... Read More
Automated Liquid Handling Robots: Bridging the Gap Between Nanoliter Liquid Handling and Larger Volume Dispensing
Wednesday, March 06, 2013
Wendy Gaisford
The introduction of automated nanoliter volume liquid handling instrumentation has revolutionized work flows, reducing the tedium of manual pipetting and the potential for manual error. In addition, ... Read More
Understanding Concentration and Evaporation Technology: Part 2: Latest Developments in System Technology
Tuesday, February 26, 2013
Induka Abeysena Rob Darrington
An understanding of the evaporative process and factors affecting it, involving careful selection of a vacuum pump, cold trap or condenser, and consideration of pressure control, is key to obtaining a... Read More
Analysis of Cathinones in Bath Salts by Direct Sample Analysis TOF/MS
Thursday, February 14, 2013
Noelle M. Elliott Avinash Dalmia Carl Schwarz Amanda M. Leffler Frank Dorman
Synthetic cathinones are gaining popularity as drugs of abuse and are often sold in bath salts. Currently, there is no standard method to quickly screen and confirm cathinones in bath salts. Read More
A Portable Multiexcitation Dispersive Raman Spectrometer for Environmental Analysis
Thursday, February 14, 2013
Huawen (Owen) Wu Jack Qian Eric Bergles Lin Chandler
Chemical examination and investigation for environmental analysis often demand portable, versatile, and real-time analytical techniques with high specificity and accuracy, and direct and noncontact ... Read More

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Spectroscopic Ellipsometry Characterization of Thin Films Used in the Food Packaging Industry

Handheld and Portable FTIR Spectrometers for the Analysis of Materials: Taking the Lab to the Sample

Fast, Efficient Antibody Biotinylation for Cleaner Immunodetection Assays

Development of a 100% Dimethyl Sulfoxide (DMSO) Sample Solution for Liquid Handler Performance Verification

A Novel Sample Preparation Method for Complete Digestion of Complex Pharmaceutical Matrices

How to Select the Best siRNA Transfection Reagent

Choosing Conservation Over Conversion: The Great Helium Debate

The Streck HbA1c-Cellular® Control: Intact Red Blood Cells for Hemoglobin A1c Testing

Point-of-Care Tests for Anemia

Detection of siRNA-Mediated Gene Modulation Using RNA Detection Probes

Working Flow Rate: How to Compare Vacuum Pumps

Measurement and Prediction of Fluid Viscosity at High Shear Rates

Automated Cell Staining in Drug Discovery

Automation in the Drug Discovery Process: Delivering Analytical Chemistry to Biologists and Beyond

Differential Scanning Calorimetry (DSC) as an Analytical Tool in Plastics Failure Analysis

Use of an Environmental Transmission Electron Microscope for Dynamic in situ Studies of Nano-Structured Materials at the Atomic Scale

Automated Liquid Handling Robots: Bridging the Gap Between Nanoliter Liquid Handling and Larger Volume Dispensing

Understanding Concentration and Evaporation Technology: Part 2: Latest Developments in System Technology

Analysis of Cathinones in Bath Salts by Direct Sample Analysis TOF/MS

A Portable Multiexcitation Dispersive Raman Spectrometer for Environmental Analysis

Product Guide

Micromachined HPLC Columns Can Revolutionize Proteomics Workflows

Buyer's Guide: GC-MS for Monitoring Environmental Pollutants

Refocusing the Lens of Cancer Screening

Study: NGS Should Be Go-to Technology on Day Zero of the Next Pandemic

Overcoming Common Challenges in Sample Viability for Single-Cell Research