Application Notes

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A Moisture Absorbing Polymer for Solvent Extraction Applications
Tuesday, April 01, 2014
Chris Pohl Kannan Srinivasan Rahmat Ullah Pranathi Perati
The moisture absorbing polymer consumable described in this article is designed to remove moisture from wet samples inline during extraction as well as from the post-extraction solvent extract. Read More
Nanoscale Infrared Spectroscopy of Polymer Composites
Tuesday, April 01, 2014
Kevin Kjoller Curtis Marcott Michael Lo Qichi Hu Eoghan Dillon Craig B. Prater
The field of polymer composites is a rapidly developing area of study in materials science. The addition of a variety of new component materials, such as carbon fibers, clay, carbon nanotubes, ... Read More
Interview With Richard Peters, President of NuAire, Inc.
Tuesday, April 01, 2014
Maria Stone
Max D. Peters started the company back in 1971. He was an avionics engineer at Honeywell and he worked on satellites, aircraft, and other projects involving HEPA [high efficiency particle air] ... Read More
Quality Control: An Important Success Factor in Nucleic Acid-Based Analysis
Tuesday, April 01, 2014
Carola Schade
Quality control (QC) is becoming increasingly important in nucleic acid-based testing. As detection technologies become more and more sensitive, final results are influenced not only by biological ... Read More
Improving the Crystallization Process for Optimal Drug Development
Friday, March 28, 2014
Michael Collazo Soheila Vaezeslami Sarah Burl
Macromolecular X-ray crystallography is an important and powerful technique in drug discovery. Studying the specific interactions of a particular drug with its protein target at the atomic level can ... Read More
Single-Cell RNA Detection to Identify Cell Subpopulations in Heterogeneous Mixtures
Tuesday, March 25, 2014
Don Weldon Victor Koong Alex Ko Yuko Williams Laura White
Traditional RNA detection methods, which analyze RNA levels in lysed, permeabilized, or fixed cell samples, make it challenging to understand the role of one gene in the context of a tissue, organ, or... Read More
Ensuring Data Integrity in Dropping Point Determination
Wednesday, March 12, 2014
Hans-Joachim Muhr
Softening and dropping point determination are established analytical tests that provide quality control for petrochemical products such as lubricating grease. However, to be accurate and comparable, ... Read More
LIMS-BPMS Coupling: A Novel Approach for Flexible End-to-End Workflow Automation in Life Science Laboratories, Part 1
Tuesday, March 11, 2014
Kerstin Thurow Silke Holzmüller-Laue Bernd Göde
Generalized life science automation (LSA) includes all application areas of laboratory automation, i.e., health care, pharmaceutical development, chemistry, and biology. The connection of all ... Read More
The Scales of Scientific Justice in Translational Science: Data Reproducibility and Verifiable Science
Tuesday, March 04, 2014
Tristan Berto
The traditional “scales of justice” represent truth and fairness. For the scientific community, the balance is between big data (terabytes of data across numerous databases) on one scale and ... Read More
Micro RNA Profiling with a Multiplexed Assay
Monday, March 03, 2014
Mark Santos
From the discovery of new miRNAs to clarifying their biological roles and utility as biomarkers, micro RNA (miRNA)-based research is undergoing a period of change. Rigorous methods are therefore ... Read More
Qualitative and Quantitative Determination of Methacrylates in Dental Filling Materials
Monday, March 03, 2014
Heidi Fleischer Kerstin Thurow Ellen Vorberg Mareike Warkentin
Various species of methacrylates are widely used in dentistry as filling materials. These consist mainly of an organic matrix, based on a monomer system of methacrylates and inorganic additives. Read More
Improved Pipetting Technique: An “Out-of-the-Box” Solution to Reduce Manual Pipetting Errors
Monday, March 03, 2014
Tanya Knaide
Handheld air-displacement pipets are used in virtually every laboratory around the world. The technique and skills of individual pipet operators are critical to the accuracy of results of liquid ... Read More
Comparative Analysis of Antinuclear Antibody and Antinuclear Antibody Spectrum
Friday, February 28, 2014
Cui Kong Jianwei Zhou Jinsong Sun Aihua Shen Qin Song Xinke Chen Li Li
The occurrence of autoimmune disease (AID) has increased 3–5% and has had a significant impact on human health. The detection of serum antinuclear antibody (ANA) is beginning to receive more attention... Read More
Electronic Pipetting: The Call for Innovation
Thursday, February 27, 2014
Paula Heimler
Take a close look around most laboratories and you will find an old, barely used fixture. No one knows who ordered it or who it belongs to. It is yellowed, dusty, and top heavy, with a small keyboard ... Read More
Automated Colony Counting: A Critical Requirement for Advanced Cancer Research
Monday, February 10, 2014
Michael Rau
The colony counting method has long been recognized as the primary method for measuring the effects of radiation, chemotherapeutic drugs, and other agents on cell viability. Read More
Seeing Molecular Interactions of Large Complexes by Cryo Electron Microscopy at Atomic Resolution
Thursday, February 06, 2014
Laurie J. Wang Z.H. Zhou
Suppose one has never seen an automobile and is asked to perform the simple task—while blindfolded—of adding gasoline to the car and checking its oil. A task like this is impossible to perform until ... Read More
Direct Sample Analysis/Time-of-Flight Mass Spectrometry
Thursday, February 06, 2014
Avinash Dalmia Andrew Tyler
There have been many developments in mass spectrometry ionization techniques in recent years, enabling the investigation of diverse sample types across the molecular weight range. Some of these ... Read More
Using Micro-XRF to Quantify Thickness and Composition of Thin-Film Solar Cells
Wednesday, February 05, 2014
Andrew Lee
Thin-film solar cells (TFSCs) have developed into a highly efficient source of energy in solar cell technology, due to the reduction in semiconductor material required compared to traditional solar ... Read More
How Solid-Phase Extraction Affects Challenges in Bioanalysis
Wednesday, February 05, 2014
Mike Oliver Tim Liddicoat Ken Meadows
Modern bioanalytical laboratories are tasked with providing high-quality analytical results from complex biological samples in a high-throughput environment. These needs have to be balanced with the ... Read More
How Lab Informatics Technologies Help Meet Evolving Healthcare Needs
Wednesday, February 05, 2014
Shooki Grasiani Don Koch Randy Hice
As U.S. healthcare providers (HCPs) navigate a changing healthcare climate, diagnostic laboratories are playing an increasingly important role in helping them prevent medical errors, lower ... Read More