Application Notes

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Determining the Quantity, Integrity, and Molecular Weight Range of Genomic DNA Derived From FFPE Samples
Friday, August 30, 2013
Donna McDade Walker
Assessing the quality and quantity of genomic DNA is a crucial step before next-generation sequencing (NGS) and DNA microarrays—for example, array comparative genomic hybridization (aCGH)—in such ... Read More
Impact of New Pipetting Techniques on Safety in the Laboratory
Monday, September 02, 2013
Bobby Chavli Annette Summers Mary Napier
According to the Occupational Safety and Health Administration (OSHA), on average, it takes between 18 and 36 months to develop and implement a new regulation, trailing the pace of science. As a ... Read More
Characterizing Nanoparticles in Liquids: Protein Aggregation Studies
Monday, September 16, 2013
Pauline Carnell Sarah Newell
Many patients’ lives have been improved with the use of monoclonal antibodies and recombinant proteins since their commercialization about 30 years ago. Work in the field of therapeutic proteins ... Read More
Automatic Motorized Leveling of Laboratory Balances
Friday, October 04, 2013
Thomas Pertsch
A fundamental rule for using high-resolution balances in pharmaceutical laboratories is that the instrument be level at all times. If the lab balance is not level, it cannot accurately measure objects... Read More
A Sensitive and Selective GC/MS Method for Analyzing Persistent Organic Pollutants Using a Novel Ionization Source
Friday, October 04, 2013
Jody Dunstan
Charge transfer chemical ionization (CI) was among the ionization types studied decades ago by researchers investigating fundamental Characteristics of chemical ionization. However, the technique was ... Read More
Analysis of Potable and Wastewaters Using An Autodilution/Calibration System and ICP-OES
Monday, October 07, 2013
Laura Thompson
In 1970, the United States government established the Environmental Protection Agency (EPA) in response to growing public demand for a cleaner environment. The Agency was not only given the ... Read More
Improved Long-Term Culture Using A Microfluidic Platform
Monday, October 07, 2013
Alex Mok Paul Hung Cindy Chen Sónia Gil Kathleen Ongena
Precise and biologically relevant in vitro studies require the ability to analyze cell responses to perturbations over time. In order to achieve successful long-term cell culture and imaging, however,... Read More
45^th Anniversary Webinar
Monday, October 14, 2013

We recently commemorated the 45th Anniversary of American Laboratory by presenting a live webinar, “The Evolution of Mass Spectrometry—History and Advances over the Last 45 Years.” Topics included the... Read More
Evaluation of Antibiotic-Free Cell Cultures in Manual and Automated Cell Handling
Monday, October 28, 2013
Kerstin Thurow Ricarda Lehmann Leonie Vetter Luisa Person
Antibiotics are frequently added to cell culture media; the greatest benefit to this is that it suppresses contamination. However, routine use of antibiotics is associated with the development of ... Read More
Analysis of Chiral Compounds in Lavender Oil Using Headspace Fast Chiral Gas Chromatography
Wednesday, November 06, 2013

Enantiomeric compounds are very important in the flavors and fragrances field. Chiral capillary gas chromatography (GC) is a proven, convenient method for characterizing oils and differentiating ... Read More
Synthesis, Characterization, and Evaluation of a Fluid Loss Agent for High-Temperature Drilling Fluid
Thursday, November 07, 2013
Xiuhua Zheng Shiwei Yang Zhongli Lei
Polymers and inorganic additives have been widely used in high-temperature water-based drilling fluids to transport rock cuttings, maintain well stability, control rheological properties, and minimize... Read More
A Map to More Reliable RT-qPCR Results Using MIQE Guidelines
Thursday, November 07, 2013
Sean Taylor
RT-qPCR (reverse transcription-quantitative polymerase chain reaction) is used routinely by a broad spectrum of researchers to assess the absolute or relative quantity of genomic DNA (gDNA) or ... Read More
Field-Deployable, Real-Time Sensor for the Monitoring of Volatile Organic Compounds (VOCs)
Thursday, November 07, 2013
Manish Gupta J. Brian Leen
Volatile organic compounds (VOCs) play an important role in atmospheric chemistry. They are critically involved in aerosol formation, tropospheric chemistry, and air quality. Read More
Validation of Metal Impurities in Drug Products
Thursday, November 07, 2013
Alan Cross
The Elemental Impurities Chapters <232> and <233> were due to appear this year in the U.S. Pharmacopeia (with similar sections in the European Pharmacopeia). The date has now been pushed back pending the ... Read More
Flow Cytometry Applied to Plant Reproductive Biology
Thursday, November 07, 2013
Diego H. Hojsgaard Elmar Herbig
Understanding how biodiversity is distributed in nature and how it is impacted by human activities has become crucial for nature conservation. Read More
Fast, Accurate Blood-Alcohol Analysis Using Headspace-Gas Chromatography
Friday, November 08, 2013

Blood-alcohol analysis is a common, important analysis for diagnostic and forensic labs. In addition to the detection of ethanol, other metabolites must be considered, such as methanol or iso-propanol... Read More
Determination of Palladium in Water and Geological Samples by Flame Atomic Absorption Spectrophotometry
Thursday, November 28, 2013
Dong Zhang Qian-Wu Wang
The precious metal palladium has been widely applied in the electronics, aerospace, chemical, metallurgy, automobile engines, and pharmaceutical industries due to its corrosion resistance, oxidation ... Read More
Identification of Cancer Stem Cells Within Mixed Populations Using Live Cell RNA Detection
Thursday, January 09, 2014
Don Weldon Steve McClellan
Despite the ubiquity of studies measuring mRNA and miRNA levels, many current techniques require cell lysis and are enormously disruptive to the cells being studied. Read More
Bottle Liquid–Liquid Extraction Update: In Situ Water Sample Preparation
Tuesday, January 21, 2014

As first described in Ref. 1, an alternative liquid–liquid extraction technique was originally conceived, born, and cultivated in an environmental lab setting to enable holding time obligations to be ... Read More
Ultrafast Confocal Raman Imaging - Application Examples
Monday, January 27, 2014

Using the Ultrafast Confocal Raman Imaging Option, a single Raman spectrum can be acquired in as few as 760 µsec. A wide variety of samples can be analyzed with the Ultrafast Confocal Raman Imaging ... Read More

Sort

Determining the Quantity, Integrity, and Molecular Weight Range of Genomic DNA Derived From FFPE Samples

Impact of New Pipetting Techniques on Safety in the Laboratory

Characterizing Nanoparticles in Liquids: Protein Aggregation Studies

Automatic Motorized Leveling of Laboratory Balances

A Sensitive and Selective GC/MS Method for Analyzing Persistent Organic Pollutants Using a Novel Ionization Source

Analysis of Potable and Wastewaters Using An Autodilution/Calibration System and ICP-OES

Improved Long-Term Culture Using A Microfluidic Platform

45^th Anniversary Webinar

Evaluation of Antibiotic-Free Cell Cultures in Manual and Automated Cell Handling

Analysis of Chiral Compounds in Lavender Oil Using Headspace Fast Chiral Gas Chromatography

Synthesis, Characterization, and Evaluation of a Fluid Loss Agent for High-Temperature Drilling Fluid

A Map to More Reliable RT-qPCR Results Using MIQE Guidelines

Field-Deployable, Real-Time Sensor for the Monitoring of Volatile Organic Compounds (VOCs)

Validation of Metal Impurities in Drug Products

Flow Cytometry Applied to Plant Reproductive Biology

Fast, Accurate Blood-Alcohol Analysis Using Headspace-Gas Chromatography

Determination of Palladium in Water and Geological Samples by Flame Atomic Absorption Spectrophotometry

Identification of Cancer Stem Cells Within Mixed Populations Using Live Cell RNA Detection

Bottle Liquid–Liquid Extraction Update: In Situ Water Sample Preparation

Ultrafast Confocal Raman Imaging - Application Examples

Product Guide

Micromachined HPLC Columns Can Revolutionize Proteomics Workflows

Buyer's Guide: GC-MS for Monitoring Environmental Pollutants

Refocusing the Lens of Cancer Screening

Study: NGS Should Be Go-to Technology on Day Zero of the Next Pandemic

Overcoming Common Challenges in Sample Viability for Single-Cell Research