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Improving the Crystallization Process for Optimal Drug Development
Friday, March 28, 2014
Michael Collazo
Soheila Vaezeslami
Sarah Burl
Macromolecular X-ray crystallography is an important and powerful technique in drug discovery. Studying the specific interactions of a particular drug with its protein target at the atomic level can ...
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Improving Refinery Laboratory Productivity 20% While Increasing Accuracy With LIMS
Thursday, March 01, 2007
Robert Hudson
In process manufacturing, a laboratory information management system (LIMS) implementation will deliver exceptional value if it eliminates redundant data transcriptions within the laboratory, ...
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Improving Protein Purification Efficiency of Biologics
Tuesday, May 01, 2018
Candice Cox
Multi-D chromatography reduces time to results and increases the robustness and reproducibility of small-batch biologic purification.
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Improving pH Measurement in Drinking Water Monitoring
Thursday, March 14, 2019
Ricki Hartwell
Advances in pH electrode technology based on iodide/triiodide reference systems and novel electrode designs are improving the reliability, stability, and longevity of pH measurement systems.
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Improving Performance of Ultrasonic Cleaners for Sieve Cleaning, Solvent Degassing, and Sample Prep
Wednesday, October 31, 2012
Bob Sandor
Ultrasonic energy, specifically ultrasonic cavitation, is widely accepted in research laboratories to accomplish multiple functions.
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Improving FTIR Operation With a Contaminant Analysis Program
Wednesday, September 01, 2010
John Monti
Spectrum search (library search) is a procedure often used in contaminant analysis. It consists of using the search function included in Fourier transform infrared (FTIR) software or specialized ...
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Improving Food Safety: How Advanced GC-MS/MS Systems Enable Fast, Accurate, and Reliable PBDE Quantification
Friday, February 22, 2019
Paul Silcock
Advances in GC-MS/MS are enabling accurate and robust quantification of PBDEs, helping food safety laboratories meet regulatory requirements and safeguard consumer health.
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Improved Sample Preparation Productivity With Selective Extraction Using Accelerated Solvent Extraction
Tuesday, August 02, 2011
Jennifer H. Peterson
Bruce E. Richter
David E. Knowles
During any extract ion process, interferences can also be extracted along with desired analytes.
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Improved Pipetting Technique: An “Out-of-the-Box” Solution to Reduce Manual Pipetting Errors
Monday, March 03, 2014
Tanya Knaide
Handheld air-displacement pipets are used in virtually every laboratory around the world. The technique and skills of individual pipet operators are critical to the accuracy of results of liquid ...
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Improved Method to Quantitate Gluten in Purified Wheat Starch
Friday, February 17, 2017
Katharina Anne Scherf
Peter Koehler
A new HPLC method may be applied as a confirmatory method to ELISA, particularly to check for the presence of glutenins in WSt rendered gluten-free.
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Improved Long-Term Culture Using A Microfluidic Platform
Monday, October 07, 2013
Alex Mok
Paul Hung
Cindy Chen
Sónia Gil
Kathleen Ongena
Precise and biologically relevant in vitro studies require the ability to analyze cell responses to perturbations over time. In order to achieve successful long-term cell culture and imaging, however,...
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Improved Liquid Biopsies With Combined Digital PCR and Next-Generation Sequencing
Friday, February 19, 2016
George Karlin-Neumann
The discovery that circulating tumor DNA (ctDNA) can be found in the blood, urine and other bodily fluids of cancer patients has led to a new type of biopsy that bypasses surgery—liquid biopsy.
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Improved Capabilities of Noncell-Based Permeability Assays
Monday, April 10, 2006
Greg Kazan
Assays that predict passive absorption of orally administered drugs have become increasingly important in the early drug discovery process.
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Implementing On-Line Nano-UHPLC Technology for Improved Productivity in Proteomics Applications
Thursday, December 01, 2011
Lasse Gaarde Falkenby
Ole Hørning
Christian Ravnsborg
Jakob Bunkenborg
Jens S. Andersen
Many laboratories performing proteomics analysis utilize conventional nano-HPLC, which can result in limited separation and ionization, reducing the productivity and amount of peptide and protein ...
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Implementation of a Centralized, Enterprise-Wide Information System in the QA/QC Environment
Saturday, March 01, 2008
Douglas Zacherl
A rapidly growing number of corporations are moving their information structure toward a more centralized, enterprise-wide model in which all the key information about their business can be readily ...
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Impact of Weighing Accuracy and Data Integrity in Forensic Drug Analysis
Friday, November 10, 2017
Tucker Rubino
Klaus Fritsch
Thomas Rohrer
To stay compliant with ever-changing regulations and withstand any challenge in court, it is critical for managers and scientists in forensic laboratories to be well-informed about the key issues ...
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Impact of New Pipetting Techniques on Safety in the Laboratory
Monday, September 02, 2013
Bobby Chavli
Annette Summers
Mary Napier
According to the Occupational Safety and Health Administration (OSHA), on average, it takes between 18 and 36 months to develop and implement a new regulation, trailing the pace of science. As a ...
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Imaging of Graphene with Confocal Raman and Atomic Force Microscopy (AFM)
Monday, January 27, 2014
Graphene is a two-dimensional material and as such is applicable in a wide variety of fields. Graphene characterization requires the use of a measurement tool that is nondestructive. An effective tool...
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Image-Based, Automated Analysis of 3-D Tumor Spheroids
Tuesday, August 07, 2018
Dmitry Kuksin
An image cytometer makes it possible for researchers to gain a deeper understanding of how drugs may affect the tumors under study.
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Image-Based Characterization of 3-D Cell Culture Models Grown in Spheroid Microplates
Tuesday, August 07, 2018
Tom Villani
Ann E. Rossi
Hilary Sherman
A high-throughput, cost-effective approach for 3-D image-based characterization of 3-D cell culture model has been developed.
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