Application Notes

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Measurement and Prediction of Fluid Viscosity at High Shear Rates
Tuesday, April 09, 2013
Tien T. Dao Jeshwanth K. Rameshwaram
Polymeric materials, in a general sense, are viscoelastic in nature since they exhibit a strong dependence of deformation and flow on time and temperature. Performance of these materials can only be ... Read More
Matrix Degradation Assays for Investigating Cell Invasion
Tuesday, November 01, 2011
Jun Ma Luke Armstrong Janet Anderl
Tumor metastasis, inflammation, and development are accompanied by the invasion of cells through the extracellular matrix. Read More
Material Characterization With Complete Compositional Analysis Using Thermogravimetry
Wednesday, January 16, 2013
Matthias Wagner Michael R. Zemo
Consistent high performance demanded from modern materials has been a topic of discussion for both technical and business individuals for many years. The globalization of the supply and ... Read More
Mass Spectrometry—The Quest for Ionization Improvements: Notable New MS Products at Pittcon 2014
Tuesday, May 06, 2014
Brian Musselman
Sitting here watching March Madness reminded me of the new instrumentation presented at Pittcon® in Chicago. Not one, but two, mass spectrometer prod- ucts were awarded a Pittcon Editors’ Award, ... Read More
Maple Syrup Color Analysis Using UV/VIS Spectrophotometry
Tuesday, November 24, 2015
Jeff Head John Kinyunjui Mark Talbott Robert Clifford
UV/VIS spectrophotometry is a valuable tool for measuring the properties of liquids and solids. Read More
Manufacturing Considerations for IVD Reagents Used in Clinical Chemistry and Special Chemistry Laboratories
Tuesday, July 25, 2017
Robert J. Janetschek Julia Nisbet-Fahy Andrew Whitehouse
To produce diagnostic reagents that meet current and future demands requires a knowledge, understanding, and appreciation of the various reagents used for clinical testing applications. Read More
Managing Workstation Exhaust at Biosafety Level Laboratories
Monday, April 03, 2006
Paul A. Tetley
Biosafety level laboratories, particularly Levels3 and 4, present special problems for managing workstation fumehood exhaust. Read More
Managing the Complexity of Microbial Biofuel Production With Integrated Informatics
Tuesday, May 09, 2017
Barbara van Cann
Integrated informatics solutions based on LIMS and chromatography data systems are helping biofuel producers ensure that processes are robust, safe and efficient. Read More
Managing Laboratory Maintenance
Tuesday, February 07, 2006
L. Wayne Collins
Other than personnel-related costs, maintenance is generally the most expensive item in the laboratory operating budget. Read More
Making Surface Tension Measurement a Practical Utility for Modern Industrial R&D
Thursday, December 01, 2005
Christoffer Johans Ilkka Palonen Pekka Suomalainen Paavo K.J. Kinnunen
Vast numbers of new surfactants are introduced annually for improved formulation and functionality in products ranging from personal care (e.g., soaps, shampoos, sun care, and cosmetics products), ... Read More
Maintaining a Quality System in the Clinical Laboratory
Thursday, June 29, 2017
Ginger Weeden
Communication, collaboration, and thorough preparation are essential to developing a quality system. Read More
Lower Pollution Limits and Refinery Flare Monitoring Require Special Gas Control Equipment for Sampling
Tuesday, April 05, 2016
Larry Gallagher
Implementation of Title 40 of the Clean Air Act has resulted in a dramatic reduction in critical air pollutants. Read More
Losses of Proteins in Gradient HPLC
Friday, August 24, 2018
Steven C. Goheen Jacqueline Hilsenbeck-Fajardo
Gradient elution of biopolymers by HPLC is an effective method for separation and quantitation. Read More
Long-Range Sequencing is Required to Unlock the Full Genome
Friday, February 19, 2016
Michael Schnall-Levin
Next-generation sequencing (NGS) provides unprecedented access to one of biology’s greatest mysteries—the genome. Read More
Long-Range Genomics Is Reviving a Lost Art
Wednesday, July 26, 2017
Chris Boles
The instrument described here was designed to treat DNA gently enough that users can prepare libraries of extremely large fragments directly from blood samples, bacterial and tissue cultures, or other... Read More
Long Reads and the Return of Reference Genomes
Thursday, February 18, 2016
Chris Boles Jonas Korlach
The availability of inexpensive, massively parallel short-read sequencers shifted the focus of high-quality reference genome production to resequencing and draft genome assemblies, emphasizing ... Read More
Liquid Handling Uses Acoustic Droplet Ejection for Improved Results
Monday, May 08, 2017
Mark Fischer-Colbrie
Acoustic drop ejection systems can pave the way for entirely new applications, bringing higher throughput and greater flexibility to many areas of biology. Read More
Liquid Biopsy Solutions for Noninvasive Molecular Profiling
Monday, June 22, 2015
Michael Schwartz
Liquid biopsy offers the potential to understand and treat cancer in ways never before possible. The concept is simple: collect tumor DNA after it enters the peripheral blood circulation and identify... Read More
Linear Transformation Applied to the Calibration of Analytes in Various Matrices Using a Total Hydrocarbon Analyzer
Friday, July 24, 2015
Michael T. Tang Grace Feng Greg Merideth Rui Huang
Total hydrocarbon analyzers provide linear responses to methane and other hydrocarbons; however, the slope and intercept measurements are dependent on the matrix. This requires that calibration be ... Read More
LIMS-BPMS Coupling: A Novel Approach for Flexible End-to-End Workflow Automation in Life Science Laboratories, Part 2
Monday, August 04, 2014
Kerstin Thurow Silke Holzmüller-Laue Bernd Göde
This article illustrates the potential of coupling a business process management system (BPMS) and LIMS, was presented in Part 1 of this paper (Am. Lab. 2014, 46[4], 26–9). Part 2 highlights the ... Read More

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Measurement and Prediction of Fluid Viscosity at High Shear Rates

Matrix Degradation Assays for Investigating Cell Invasion

Material Characterization With Complete Compositional Analysis Using Thermogravimetry

Mass Spectrometry—The Quest for Ionization Improvements: Notable New MS Products at Pittcon 2014

Maple Syrup Color Analysis Using UV/VIS Spectrophotometry

Manufacturing Considerations for IVD Reagents Used in Clinical Chemistry and Special Chemistry Laboratories

Managing Workstation Exhaust at Biosafety Level Laboratories

Managing the Complexity of Microbial Biofuel Production With Integrated Informatics

Managing Laboratory Maintenance

Making Surface Tension Measurement a Practical Utility for Modern Industrial R&D

Maintaining a Quality System in the Clinical Laboratory

Lower Pollution Limits and Refinery Flare Monitoring Require Special Gas Control Equipment for Sampling

Losses of Proteins in Gradient HPLC

Long-Range Sequencing is Required to Unlock the Full Genome

Long-Range Genomics Is Reviving a Lost Art

Long Reads and the Return of Reference Genomes

Liquid Handling Uses Acoustic Droplet Ejection for Improved Results

Liquid Biopsy Solutions for Noninvasive Molecular Profiling

Linear Transformation Applied to the Calibration of Analytes in Various Matrices Using a Total Hydrocarbon Analyzer

LIMS-BPMS Coupling: A Novel Approach for Flexible End-to-End Workflow Automation in Life Science Laboratories, Part 2

Product Guide

Micromachined HPLC Columns Can Revolutionize Proteomics Workflows

Buyer's Guide: GC-MS for Monitoring Environmental Pollutants

Refocusing the Lens of Cancer Screening

Study: NGS Should Be Go-to Technology on Day Zero of the Next Pandemic

Overcoming Common Challenges in Sample Viability for Single-Cell Research