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Transformation of a University Teaching Laboratory Through Innovative Solutions
Tuesday, June 01, 2010
Steve McDaniel Michael Kihn
This article describes the improvements made to a 4500-square-foot chemistry teaching laboratory within the University of Pennsylvania’s (Philadelphia) Chemistry ’58 building. The design was led by ... read more
Transferability of Pipet Calibrations and Proficiency of Operators: Prerequisites for Method Validations and Method Transfers
Friday, September 25, 2009
A. Björn Carle George W. Rodrigues Richard H. Curtis
Data quality and integrity are among the most important issues for any laboratory, and one of the most obvious ways to maintain quality in a laboratory setting is regular instrument calibration. read more
Total Nitrogen in Water by High-Temperature Catalytic Combustion and Chemiluminescence Detection
Tuesday, February 17, 2015
William Lipps
There are currently no promulgated U.S. EPA methods for the determination of total nitrogen in ambient water and wastewater. There are approved methods for the determination of inorganic nitrogen (NO3... read more
Timeline for Building the Francis Crick Institute
Tuesday, January 17, 2017
Robert L. Stevenson, Ph.D.
The UK Centre for Medical Research and Innovation (UKCMRI) (now known as the Francis Crick Institute) was established in response to the need for an organization dedicated to improving healthcare in ... read more
Three-Dimensional Elemental Imaging Using a Confocal X-Ray Fluorescence Microscope
Saturday, April 01, 2006
Brian M. Patterson George J. Havrilla
Micro X-ray fluorescence (MXRF) is a powerful elemental technique that can nondestructively provide both single-point spectra and full spectral elemental maps. read more
Three Issues of LIMS/Laboratory Informatics That Can Cost Money
Saturday, December 01, 2007
Gloria Metrick
Laboratory information management system (LIMS) and laboratory informatics (LI) projects still have too many significant cost overruns, as do many other software projects. read more
Thermosets: How to Avoid Incomplete Curing
Friday, January 01, 2010
Steve Sauerbrunn Rudolf Riesen
Oligomers and monomers that react and polymerize to form a rigid network with elevated temperatures are called thermosets. Thermosetting oligomers have been used for several decades to produce ... read more
Thermal Analysis of Biodegradable Material: From Modulated Temperature DSC to Fast Scan DSC
Wednesday, August 01, 2007
Peng Ye Krista Swanson Fiorini
Synthetic polymers derived from petroleum products are used widely on a daily basis. read more
The World of Separation Science: Advanced Column Technology Forces Next-Generation Instrumentation at HPLC 2011
Wednesday, August 17, 2011
Robert L. Stevenson, Ph.D.
Throughout the development of HPLC, advances in column performance, primarily efficiency, have exposed deficiencies in instrumentation performance, leading to another generation. read more
The Use of Magnetic Beads in Microfluidic Binding Assays and On-Chip Enzymatic Microreactions
Monday, February 01, 2010
Toni Ann Riveros Roger Lo Xiaojun Liu Ariana Valdez Marisa Lozano Frank A. Gomez
Miniaturization has allowed for the development of a myriad of microfluidic platforms that offer a host of advantages over conventional analytical techniques, including small sample volume ... read more
The Time has Come for a Forensic Laboratory Improvement Act
Tuesday, January 15, 2013
Robert L. Stevenson, Ph.D.
Forensic laboratories are relied upon to provide science-based evidence for a variety of purposes and stakeholders. Since people’s lives are involved, the reports generated need to be based on the ... read more
The Story of MALS
Saturday, October 05, 2013
Philip J. Wyatt
The concept of measuring light scattered from a solution at each of a plurality of angles simultaneously began in late 1976 in a very unlikely application. At that time, scientists from Science ... read more
The State of Microscopy for 2012
Tuesday, November 01, 2011
Barbara Foster
In various recent interviews, I’ve been asked about the state of microscopy and, most specifically, the rise of technologies such as AFM (atomic force microscopy) and Raman confocal and the ... read more
The Search for Promising Viral Targets in Drug Discovery
Wednesday, August 08, 2007
Colleen B. Jonsson Lucile White James Noah William Severson Marintha Heil
In the past decade we have seen advances in laboratory automation and in assays used to assess biological endpoints. read more
The Role of the Anaerobic Chamber in Microbiology Today
Wednesday, May 26, 2010
Brian Coy
The anaerobic chamber, developed more than 40 years ago for microbiologic use, has evolved with operators’ needs and remains a significant tool for research and other applications worldwide. read more
The Role of Synthetic DNA in Big DNA and Genetics Research
Friday, August 02, 2013
Dan Gibson Hans Packer
Synthetic biology is defined as the de novo design and construction of biological devices and systems, and as such is heavily reliant on the use of synthetic DNA. The size and sequence of potential ... read more
The Role of Optical ICPs in Environmental Analyses
Monday, October 01, 2007
Matthew Cassap
Over the last 50 years, there has been increasing legislation relating to environmental protection and quality. read more
The Role of Analytical Instrumentation in the Life Sciences
Saturday, November 01, 2008
Robert L. Stevenson, Ph.D. C. David Carr
Historically, the life sciences have been qualitative in nature, seeking to identify but seldom understand quantitatively. read more
The Road to Better Cell Culture Outcomes
Wednesday, September 01, 2010
David Craig
In an environment literally covered in microorganisms, keeping cell cultures contaminant free is both challenging and essential. read more
The Paperless Laboratory: Automated Lab Instrument Qualification on an iPad or PC
Thursday, January 17, 2013
Joe Tehrani
One of the most time-consuming and costly tasks in a regulated laboratory is periodic qualification of instruments. For laboratories to improve productivity and reduce costs while also meeting ... read more