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Advances in Microscale Protein Fractionation and Analysis
Fractionation is an essential step in the identification of proteins and their subsequent structural characterization.
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Ultrasensitive Measurement of Protein and Nucleic Acid Biomarkers for Earlier Disease Detection and More Effective Therapies
It is a universal fact substantiated by decades of biopharmaceutical research: the earlier a disease is detected, the more likely treatments will be effective in alleviating or stabilizing the disease...
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Calorimetry: Getting the Winning Combination
Ultrasensitive calorimetric instruments for measuring very small heats of reaction at constant temperature (isothermal titration calorimetry [ITC]) and small heat effects induced by temperature (...
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Pipets and Ergonomics: What Matters Most
The handheld pipet is perhaps the most ubiquitous piece of equipment in any laboratory.
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A Collaborative Building Design That Provides Research Space for Childhood Neurological Diseases
According to the World Health Organization, 1 billion people worldwide, including 300 million children, are affected by neurological disease.
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Simultaneous Crystallization Testing in a Laboratory Furnace
A previous paper described a model of an air-cooled test tube with a series of sockets and plugs (crystallization socket-outlet adaptor) installed in a laboratory chamber furnace, the goal of which ...
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Bioassays 2011
During the last decade, tremendous strides have been made in proteomics and genomics.
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Seventh Annual Semantic Technology Conference (SemTech 2011): Natural Language Processing Catches up to Large-Scale Integration
In 2009, when I attended the Semantic Technology Conference in San Jose, CA, the meeting was a mixture of software developers and applications reports. Many were from scientists seeking to improve ...
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TGA With Evolved Gas Analysis
In thermogravimetric analysis (TGA), the weight of a sample is recorded as a function of temperature or time under defined atmospheric conditions.
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A High-Sensitivity Sensor for DSC
A dramatic increase in sensitivity at low signal noise without a significant loss in signal resolution has been achieved with the HSS7 high-sensitivity sensor.
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Methodologies for Stabilization of Pharmaceuticals in Biological Samples
The instability of small drug molecules in biological fluids causes serious bioanalytical challenges, regardless of what type of powerful analytical technology is employed for the bioanalytical ...
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A New Approach to Atomic Force Microscopy for Nanometrology Applications
Since the invention of the atomic force microscope (AFM), the use of high-resolution topographic images has become the standard in microscopy and surface science publications.
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New Frontiers in Chromatography
High-performance liquid chromatography (HPLC) has proven to be the predominant technology used in laboratories worldwide during the past 30-plus years.
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Multicapillary Columns for Chromatography
The principles and theory of high-speed capillary chromatography have been known since the 1960s. To realize the maximum speed capabilities, it is necessary to use capillaries with a diameter of ...
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Creating Rich Web-Based LIMS With Programmable XML Technologies
Laboratory information management systems convert mass amounts of data into analytical information useful throughout the enterprise.
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