Super SESI-HRMS: Real Time Analysis of Dynamic Metabolic Processes

In the last ten years, we have developed the tools required to analyze dynamic changes in metabolism. A key technical challenge was to detect large and biologically relevant molecules in the gas phase, which allowed for the analysis of respiration metabolites. This article describes and illustrates this new window into the metabolism and the volatilome. With an exclusive look at high ionization efficiency of Secondary Electro-Spray Ionization (SESI) and Super SESI application.

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