Per- and polyfluorinated alkyl substances (PFAS) are prevalent in aqueous environments and known to be potentially harmful if they accumulate in the human body. Precise and reliable PFAS analysis of drinking water sources is, therefore, imperative, and can be achieved using advanced liquid chromatography–tandem mass spectrometry (LC-MS/MS) in combination with automated solid-phase extraction (SPE) and combustion ion chromatography (CIC) – as described in this article.
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