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Hydrogen/Deuterium Exchange-MS for Biologics: Higher-Order Structure Analysis and Epitope Mapping
Monday, January 01, 2018
Yoshitomo Hamuro
Biologics are the fastest-growing sector in the pharmaceutical industry, with global sales approaching $200 billion and making up about 20% of all pharmaceuticals.
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The Growth of Mass Spectrometry in the Clinic
Friday, January 20, 2017
Lisa Thomas
Bradley Hart
The use of MS in the clinical laboratory really took off with liquid chromatography-tandem mass spectrometry. Its adoption over the last 15 years has been driven by the need for greater immunoassay ...
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Timeline for Building the Francis Crick Institute
Tuesday, January 17, 2017
Robert L. Stevenson, Ph.D.
The UK Centre for Medical Research and Innovation (UKCMRI) (now known as the Francis Crick Institute) was established in response to the need for an organization dedicated to improving healthcare in ...
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Trends in Biobanking
Tuesday, July 26, 2016
Martin Frey
In the early days of biobanking, biological sample collections were usually associated with a specific research area and stored near the collection point.
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Fighting Resistance With Calorimetry: New Tools for Antimicrobial Drug Development
Thursday, November 19, 2015
Magnus Jansson
Antibiotic-resistant bacteria are a growing concern, and with good reason—an estimated 23,000 deaths and two million illnesses occur annually in the U.S.
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Diagnostics From the Chemistry Laboratory to the Point of Care: An Interview With Shane Needham of Alturas Analytics, Inc.
Friday, September 25, 2015
Robert L. Stevenson, Ph.D.
The disease discovery and therapy workflow is lengthy and convoluted, with the potential for technical, regulatory and turf issues.
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A Molecular Diagnostic Platform for Use in the Physician’s Office to Treat Infectious Disease
Tuesday, April 28, 2015
Ihor Boszko
Shana Kelley
The current standard of care for infectious disease management typically involves a nucleic acid amplification test (NAAT) to produce a definitive diagnosis. Due to the complexity of molecular ...
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2014 Emerging Clinical & Laboratory Diagnostics: The Portable Lab
Monday, October 06, 2014
Robert L. Stevenson, Ph.D.
For decades, the clinical laboratory has been recognized as the leading model for applied analytical chemistry labs. Clinical chemists are the first to deal with real-world concerns such as large-...
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Precision Medicine Will Digitize Humans, But Who Pays?
Thursday, November 07, 2013
Robert L. Stevenson, Ph.D.
In a serendipitous confluence of events, I was finishing the 2013 edition of Eric Topol’s book, "The Creative Destruction of Medicine: How the Digital Revolution will Create Better Health Care," ...
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How Personalized Medicine Led to the Convergence of LIMS and LIS
Friday, October 04, 2013
Trish Meek
When the Human Genome Project mapped all 20,000+ genes in the human body in the late 1990s and early 2000s, it cost roughly $3 billion.
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New Drug Development Tools (DDT): Connecting the Dots Between Biomarker Discovery and Improved Patient Outcomes
Tuesday, August 06, 2013
Robert L. Stevenson, Ph.D.
For at least two decades, biological markers, or biomarkers, have been promoted as key advances in scientific discovery that provide a measure of biological function. Researchers and, indeed, the ...
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