Blog

A Method to Separate and Characterize Modified Forms of Histones Using HILIC and Electron Transfer Dissociation-Mass Spectrometry
Friday, January 23, 2009
Histone proteins are the highly basic core proteins of nucleosomes and play an important role in DNA regulation through post-translational ... Read More
Measuring the Heat of Evaporation by TGA/DSC
Thursday, January 01, 2009
Heat of evaporation is the amount of heat required to make a physical change from the liquid phase to the gas phase. Read More
Identifying Pharmaceuticals in Surface Water Using LC-MS/MS in Both Positive and Negative Ion Modes
Thursday, January 01, 2009
Compounds such as antibiotics, over-the- counter medicines, and caffeine drain through the sewage system largely unaltered into rivers and streams, ... Read More
The Use of Pressurized Liquid Dispensing Containers (PLDCs) With Flammable Liquids in Laboratories
Thursday, January 01, 2009
Large quantities of flammable solvents are used in today’s high-throughput analytical and biopharmaceutical laboratories. To minimize hazards, these ... Read More
Volume 41, Number 1
Thursday, January 01, 2009
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Detecting the Future of Bioscience
Saturday, December 13, 2008
The potential to use antibodies as research tools has been known since the early 1890s, when Karl Landsteiner used antibodies to distinguish between ... Read More
Achieving Consistency and Reproducibility in Cell-Based Research
Friday, December 05, 2008
In recent years, advances in mammalian cell-based research have enabled many scientific and medical discoveries. Read More
Statistics in Analytical Chemistry: Part 32—Detection Limits Via 3-Sigma
Friday, December 05, 2008
As was mentioned in the first article on detection limits (DLs) (Part 26, American Laboratory, June/July 2007), many formulas exist for calculating ... Read More
Making Single-Molecule Sequencing a Reality
Friday, December 05, 2008
The quest to directly sequence individual strands of DNA has challenged genomic technologists for decades. Read More
Desktop Biological Nanopatterning Using Dip-Pen Nanolithography
Friday, December 05, 2008
The ability to control the size and shape of deposited chemical structures on the nanoscale opens up new and exciting possibilities for the ... Read More
An Immunoaffinity Capillary Electrophoresis Biomarker Analyzer for Use in Toxicoproteomics Research
Friday, December 05, 2008
The slow pace of discovery of new protein biomarkers of toxicity or “toxicity signature protein/peptides” is partially due to the lack of high-... Read More
WS-CRDS: Precision Trace Gas Analysis and Simplified Stable Isotope Measurements
Friday, December 05, 2008
Wavelength-scanned cavity ring-down spectroscopy (WSCRDS) is fast gaining worldwide acceptance as a superior tool for trace gas analysis, because it ... Read More
What is “Hot” in Column Technologies for Liquid Chromatography?
Thursday, December 04, 2008
It has been just over 100 years since Russian botanist Mikhail Semionovich Tswett invented the separation technique that he named chromatography. Read More
Improving the Laboratory Work Experience When Homogenizing
Friday, November 28, 2008
It is no secret to researchers who homogenize tissue samples as part of their regular laboratory routine that the job can be messy and loud, and ... Read More
High-Throughput Cell Cycle Analysis Using a Microplate Cytometer
Friday, November 28, 2008
The traditional method of determining the cell cycle phase of individual cells is by quantifying their total DNA content using flow cytometry. Read More