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Laser Diffraction: A Firm Foundation for Particle Characterization
For manufacturers of solid and/or particulate products, particle size is frequently a critical parameter, and is one of the principal variables routinely used to characterize their materials.
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Environmental Testing: Paving the Path Toward a Healthier Earth
We humans are an integral part of our environment—our skies, rivers, oceans, forests, and the land.
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Increased IEF Throughput Using a Dual-Electrode Assembly
An isoelectric focusing (IEF) apparatus capable of operating at 12,000 V maximum voltage enables isoelectric focusing of proteins in immobilized pH gradients (IPGs) to be completed in less than 3 hr.
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Highlights From Joint Congress 2011: One Era Ends in Disappointment and Another Begins*
In an opening plenary, Prof. Barry Karger of the Barnett Institute of Chemical and Biological Analysis concisely defined analytical chemistry as “The science of generating relevant information by ...
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Call for Images
Would you like to see you image on the cover of American Laboratory?
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Impact of HTS on Multidetection Microplate Readers and Benefits For Life Science Research Laboratories
The basic concept behind high-throughput screening (HTS) is a numbers game: If one has the technical ability to test thousands upon thousands of potential drug compounds against a specific target, it ...
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Protein Stability Monitored by Fourier Transform Infrared Spectrometry
Degradation of proteins during storage or processing is a major concern in both manufacturing and research.
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Application of Difference Spectroscopy to Biopharmaceutical Formulation Development
Spectroscopy is increasingly being used in biopharmaceutical formulation development to characterize protein structure and the response of structure to the formulation configuration.
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Peptide De Novo Sequencing With MALDI TOF/TOF: A Simple Approach Using Sulfonation Chemistry
One of the main focuses of the scientific community, now that major advances have been achieved in the comprehension of genome organization, has become the study of proteins, including their structure...
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Rapid Screening of Complex Mixtures by Thin Layer Chromatography–Bioluminescence
The screening of complex mixtures such as foodstuffs, beverages, dietary supplements, and wastewater for toxins and adulterants or potential biological activity is often expensive and time consuming.
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Microfiltration Technology: A Sensible Approach to Automating Sample Preparation
In the world of laboratories, the discerning eye of an efficiency expert must wince while witnessing sample preparation.
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Influence of Instrumental Conditions on the Electrospray Ionization Mass Spectrometry of Peptides/Proteins in Mixtures
The simultaneous detection of several peptides or proteins in mixtures is an integral part of expression proteomics investigations.
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Cost-Effective DNA Analyzers for Increased Quality and Productivity in Sequencing and Genetic Analysis
In the past decade, advancements in DNA analysis technologies have had an enormous impact on the progress of life science research and have fueled the genomics revolution.
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Microcalorimetry: A Powerful Tool for Characterizing Amyloid Fibril Formation
Many soluble proteins misfold and form insoluble amyloid fibrils. This process occurs in many neurodegenerative disorders, such as Alzheimer’s disease, amyotrophic lateral sclerosis, Parkinson’s ...
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Reducing Cell Culture Costs By Reducing Serum Levels
Cell culture is a very important research tool today, but one that is also very expensive to use.
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