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A Novel Approach to 3-D Biological Sample Analysis Using a Dual-Beam FIB/SEM
Early interpretations of biological structures using film-based transmission electron microscopy (TEM) images were based on the analysis of two-dimensional TEM images, or by the painful reconstruction...
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Establishing a Microbial Control Strategy for Active Pharmaceutical Ingredients
In the pharmaceutical industry, defining the control strategy for a new active pharmaceutical ingredient (API) is a main goal during development of the process for its commercial manufacture.
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Easy Transition From Assay Development to High-Throughput Screening
A critical factor in achieving success with any assay is to ensure that the assay detection instrumentation is compatible with the reagents being used.
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A Noninvasive Method for Deep Raman Spectroscopy of Living Tissue and Powders
Many analytical applications require fast, noninvasive characterization of deep regions of diffusely scattering (turbid) media, such as living tissue and powders, with high chemical specificity.
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An Automated Surface Plasmon Resonance-Based System
Over the past 15 years, label-free, real-time biomolecular interaction analysis has established itself across a broad spectrum of disciplines from drug discovery to basic life science R&D.
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A Research Tool for Sample Preparation and Microfluidics
Precision ultrasonic microvortexing is an underexplored area in biophysics research, a pathway to automation for portable lab-on-a-chip (LOC) systems, biodetection, assays, and screening.
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Use of High-Content Tools to Drive Innovation and Collaboration in the Biotechnology Industry
The biotechnology industry has been hit hard by the current financial crisis and faces a future where efficiency and collaboration will be prerequisites for survival.
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Plate Washing in 1536: Evaluation of a Double-Column Aspirator Head
Plate assays (1536-well) that require washing (i.e., enzyme-linked immunosorbent assays [ELISAs] and cell-based), are not routinely implemented in high-throughput screening laboratories due to the ...
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Providing Gases for LC-MS Systems in a Safe, Convenient, and Cost-Effective Manner
A liquid chromatographic system with a mass spectrometric detector (LC-MS) requires a supply of nitrogen as the curtain gas, pure zero grade air as the source gas, and dry (–40 °F dewpoint) air as the...
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Professional LIMS Delivered On-Demand
Scientific laboratories are at the heart of most breakthroughs, investigative discoveries, and product development efforts in science-related operations.
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TIRF Microscopy Software for Automated Vesicle Fusion Detection
The recent explosion in the use of total internal reflection fluorescence (TIRF) microscopy to learn about cell trafficking means that there is an urgent need for software capable of annotating the ...
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Increasing Throughput and Lowering Detection Levels in ICP-MS Analysis Using a Microwave Digestion Quartz Rotor for Sample Preparation
Analytical chemists are being asked to perform trace and ultratrace metals analysis on a routine basis.
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Transferability of Pipet Calibrations and Proficiency of Operators: Prerequisites for Method Validations and Method Transfers
Data quality and integrity are among the most important issues for any laboratory, and one of the most obvious ways to maintain quality in a laboratory setting is regular instrument calibration.
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DSC–Microscopy
Differential scanning calorimetry (DSC) has been the primary thermal analysis tool since its inception many decades ago.
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Quality Checking for High-Throughput Screening
Chemical screening requires methods for the liquid handling of chemical compounds.
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