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Analysis of Opioids Using Isotope Dilution With GC/MS/MS
Developing methods for the analysis of drugs of abuse has become a priority for forensic toxicology and law enforcement. The large variety of illicit drugs and new and so-called “designer drugs” has ...
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Use of Heat Stabilization to Preserve Lipids and Improve Sample Quality
Lipids have long been considered to be mere building blocks of cell membranes or energy-storage molecules. It is now evident, however, that these small, nonpolymeric molecules play several key roles ...
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Automating and Validating Analysis in High-Throughput Single-Cell Assays
While genomics and transcriptomics provide insight into the potential of a cell, single-cell phenomic data reflect its current reality, allowing researchers to determine how genomic variants affect ...
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Liquid Biopsy Solutions for Noninvasive Molecular Profiling
Liquid biopsy offers the potential to understand and treat cancer in ways never before possible. The concept is simple: collect tumor DNA after it enters the peripheral blood circulation and identify...
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QIAGEN
Purifying nucleic acids from FFPE samples can be challenging. The quality of the purified nucleic acids depends on a number of factors, including how the samples were handled before, during and after ...
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NIST Shrunk the EPR Machine
When I was in graduate school, electron paramagnetic resonance (EPR) instruments were the size of a Volkswagen Beetle and weighed about four tons.
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Linear Transformation Applied to the Calibration of Analytes in Various Matrices Using a Total Hydrocarbon Analyzer
Total hydrocarbon analyzers provide linear responses to methane and other hydrocarbons; however, the slope and intercept measurements are dependent on the matrix. This requires that calibration be ...
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Volume 47, Number 6
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Sampling Cells and Tissues
Human cell and tissue sampling has become a hot topic, as evidenced by recent coverage in The New York Times and other media outlets.
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A Review of Quetzal: A Linguistic Search Engine for Biomedical Literature
Quetzal is a biomedical literature search engine that uses simple strategies that contain few keywords combined with an extensive biomedical vocabulary and filter sets that mirror the discovery ...
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Obama’s Environmental Move
President Obama did the right thing—the smart and the responsible thing—in announcing new goals to reduce carbon emissions.
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Evolving Software Enables Smarter Workflows: An Interview With Gene Tetreault of BIOVIA
The digital revolution in the laboratory began in the late 1960s, with digital integrators measuring the area of chromatographic peaks in microvolt seconds.
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Reference Standards Address Technical Challenges in DNA Resequencing
The extensive workflow required to analyze DNA samples using next-generation sequencing (NGS) leaves many opportunities for the introduction of variability.
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A Tandem Approach to TOC Analysis in Drinking Water Treatment
In 1974 Congress passed the Safe Drinking Water Act (SDWA) to regulate the nation’s drinking water supply.
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Time-Efficient Execution of Rheological Tests in Oscillation With an Easy-to-Use Quality Control Rheometer
Quality control managers are under constant pressure to conduct analyses as efficiently and cost-effectively as possible. In certain industries, such as paints and coatings and food, rheological ...
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