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A Molecular Diagnostic Platform for Use in the Physician’s Office to Treat Infectious Disease
Tuesday, April 28, 2015
The current standard of care for infectious disease management typically involves a nucleic acid amplification test (NAAT) to produce a definitive diagnosis. Due to the complexity of molecular ...
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Identification of Microplastics in the Marine Environment by Raman Microspectroscopy and Imaging
Tuesday, April 28, 2015
Each year, 5–13 million tons of plastic debris enter the oceans. The main reason for this is the inappropriate disposal of waste from industrialized nations.
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Kerafast: Connecting Scientists and Providing “Reagents for the Greater Good”
Monday, April 27, 2015
We had the opportunity to interview Jennifer Rossi, Ph.D., Chief Operating Officer of Kerafast (Boston, Mass.; kerafast.com), to find out how the online platform connects scientists and improves ...
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Volume 47, Number 3
Monday, April 27, 2015
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Portable Raman Microscopy: Laboratory-Quality Results Measured Anywhere
Bio-Rad
Wednesday, April 22, 2015
While handheld portable Raman is now well established, until recently, microRaman had yet to make the leap out of the laboratory and into the world at large. To meet that challenge, BioTools (Jupiter...
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Resistant
Wednesday, April 22, 2015
By now you are well aware of the threat. You may have even contributed to its growth. Should you worry? Task forces have been formed. There are government agencies on the case and executive orders ...
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An Automated System to Improve Western Blot Processing
Wednesday, April 22, 2015
Western blot assays provide important information about the presence and levels of protein expression. The first step in the procedure is the lysis of cells or tissues followed by solubilization of ...
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Point-of-Care Diagnostics at the 22nd International Molecular Medicine Tri-Conference
Wednesday, April 22, 2015
Point-of-care diagnostics (POC) was an important track at the 22nd International Molecular Medicine Tri-Conference, held February 15–20, 2014, in San Francisco, Calif. According to Jeffrey DuBois, Ph....
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Use of Transgenic Mouse Models to Test for Carcinogenicity
Tuesday, April 21, 2015
Carcinogenicity studies are conducted to determine the tumorigenic potential of pharmaceuticals and chemicals, as required by regulatory authorities. Two-year bioassays in rats and mice have ...
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Liquid Biopsy Symposium at Molecular MedTri-Con 2015
Tuesday, April 21, 2015
The hottest track at the 2015 Molecular Med Tri-Con was circulating nucleic acids. Circulating tumor cells were also sizzling, leading to the question: “Which is most important?”
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Application of HPLC in the Synthesis of 2,4,5-Trifluorobenzoic Acid
Monday, April 20, 2015
An important fine chemical intermediate for pharmaceuticals, agrichemicals and polymers, 2,4,5-trifluorobenzoic acid (2,4,5-TFBA) is synthesized from tetrachlorophthalic anhydride via hydrolysis, ...
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Fracking is Changing America
Friday, April 17, 2015
Fracking continues to change America, generally for the good. The Wall Street Journal1 reported that 49% of domestic petroleum production in March 2015 was product derived from fracked shale rock ...
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Simplified Bioanalytical Sample Preparation
Wednesday, April 08, 2015
The complexity of biological samples can pose challenges to downstream analysis in the pharmaceutical industry. Bioanalytical and drug metabolism and pharmacokinetics (DMPK) groups often work with ...
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Evaluation of an Automated Solid-Phase Extraction Method Using Positive Pressure
Wednesday, April 08, 2015
Investigations for the determination of drugs in real samples, while gaining in importance, are limited by time and sample throughput. In response to this, the authors developed an automated solid-...
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Validation of a Magnetic Bead Mixer on an Automated Next-Generation Sequencing Library Preparation System
Tuesday, April 07, 2015
Reduced costs and higher throughput have made next-generation sequencing (NGS) more accessible to users in such diverse fields as diagnostics, infectious disease, food safety and public health. NGS ...
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