Application Notes

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1-mm-i.d. Monolithic HPLC Columns for High-Efficiency Protein Separations
Tuesday, September 01, 2009
Sebastiaan Eeltink Remco Swart
The preparation of monolithic separation media for HPLC composed of a single, continuous polymer macroporous support has been reported since the late 1960s. Due to its unique material properties, ... Read More
Knowledge Management and Efficiency Gains
Tuesday, September 01, 2009
Paul Denny-Gouldson Eliot Randle
In the face of escalating R&D costs, currently estimated at $800 million U.S. to produce a new drug, the life science discovery industry is constantly searching for ways to control expenditure, ... Read More
A Nondestructive Technique for the Detection of Metallic Impurities in Alloys
Tuesday, September 01, 2009
John R. Dannecker Neil D. Fichtelberg Scott A. Knowles
Examples of welds contaminated with small quantities of incorrect weld filler metal were recently discovered in fabricated assemblies. The presence of such impurities, which are not detectable using ... Read More
Use of Rotational Vane Rheometry to Solve Practical Problems
Saturday, August 01, 2009
David J. Moonay
Rheology is the study of the deformation of matter. A common definition is that rheology is the study of flow. Viscometry, in particular, is the measurement of viscosity or the resistance to flow. ... Read More
Sediment Standard Reference Materials
Saturday, August 01, 2009
Michele Schantz Rolf Zeisler
The National Institute of Standards and Technology (NIST, Gaithersburg, MD) issued a new series of Standard Reference Materials® (SRMs) targeting the ever-increasing list of potentially toxic ... Read More
A Novel Approach to Particle Size Measurement in the Single-Nanometer Range
Saturday, August 01, 2009
Yanyin Yang Robert H. Clifford Gilbert Vial Haruo Shimaoka
Nanotechnology is pervasive, as evidenced by the abundance of information found in the latest scientific journals. What is nanotechnology? According to the National Nanotechnology Initiative, “a ... Read More
Automating Sample Preparation in the Metals Laboratory
Saturday, August 01, 2009
Joe Boyd
Preparing samples for analysis is an extremely time-consuming task. In fact, sample preparation steps can easily take up more time in the laboratory than the actual analysis. With autosamplers on ... Read More
Portable IR Analyzers: The Ideal Measurement Solution for Biofuels Blend Quality and Wastewater Testing
Wednesday, July 01, 2009
Sandra Rintoul
Two challenges facing the biofuels industry involve compliance with blend quality standards and wastewater regulations. According to a study done by the National Renewable Energy Laboratory, the chief... Read More
ICP Spectrometry Coupled With a Separate Sampling and Excitation Accessory for Rapid Analysis of Impurities in Silver
Wednesday, July 01, 2009
George Buchbinder Nikolai Verblyudov Andrew Clavering
Silver is one of the oldest metals known to humanity and is still very important in minting, jewelry, and industry. Silver can be obtained from pure deposits and ores and, like other precious metals, ... Read More
Using a Purge-and-Trap Concentrator for Newly Proposed U.S. EPA Method 524.3
Thursday, June 18, 2009
Teri Dattilio
Purge-and-trap (P&T) concentration along with GC analysis is a widely used method for the detection of volatile organic compounds (VOCs). This methodology was developed to achieve the high sensitivity... Read More
Determination of Metal Impurities Present in Solar-Grade Bulk Silicon by ORS-ICP-MS
Thursday, June 18, 2009
Junichi Takahashi
Research into alternative energy sources is accelerating, with one of the most dynamic areas of interest being the development of devices to harness solar energy. Some industry experts, including the ... Read More
A Versatile Substrate Coated With Silver Nanoparticles for Surface-Enhanced Vibrational Spectroscopy
Thursday, June 18, 2009
Beng Guat Ooi Lijie Zhao Ngee-Sing Chong
Both infrared and Raman spectroscopic techniques are useful for probing the structure of complex molecules. However, they are typically not as sensitive as mass spectrometric techniques and hence have... Read More
An Improved Protocol for the Analysis of Alcohols by Direct Analysis in Real Time Mass Spectrometry
Thursday, June 18, 2009
James A Laramée H. Dupont Durst J. Michael Nilles Theresa R. Connell
It was previously reported that when Direct Analysis in Real Time (DART™) (JEOL USA, Inc., Peabody, MA) mass spectrometry was applied to the analysis of very pure alcohols, their mass spectra were ... Read More
Food Safety: The Value of LIMS in This Regulated Environment
Thursday, May 28, 2009
Colin Thurston
The U.S. Food and Drug Administration (FDA) has issued a number of regulations to ensure the safety of food manufactured, distributed, exported, and imported in the U.S. The Federal Food, Drug and ... Read More
A Novel Approach to 3-D Biological Sample Analysis Using a Dual-Beam FIB/SEM
Thursday, May 28, 2009
Ben Lich
Early interpretations of biological structures using film-based transmission electron microscopy (TEM) images were based on the analysis of two-dimensional TEM images, or by the painful reconstruction... Read More
Easy Transition From Assay Development to High-Throughput Screening
Thursday, May 28, 2009
Peter Banks Xavier Amouretti Karen Kleman-Leyer Brad Larson Tracy Worzella
A critical factor in achieving success with any assay is to ensure that the assay detection instrumentation is compatible with the reagents being used. Read More
Evolving Products in the Homogenizing Field
Friday, April 17, 2009
Brian Archibald
As technology moves forward in laboratory research and development, new products are emerging within the field of sample preparation. Read More
Automated ELISA Liquid Handling With a Combination Microplate Washer Dispenser
Friday, April 17, 2009
Paul Held Jason Greene
Many biochemical assays involve the addition of different reagent fluids interrupted by delays or incubations to allow for a reaction to occur. Read More
Selecting Centrifuge Consumables
Friday, April 17, 2009
Tammy Goodman
Selecting a centrifuge and rotor can sometimes feel like the easy part when faced with choosing the consumables in which to centrifuge samples. There are many suppliers of centrifuge tubes to choose ... Read More
A Chromatography Detector for Multicomponent Analysis of Macromolecules and Polymers
Friday, April 17, 2009
Jason Sanchez Paul Clarke Jean-Luc Brousseau
The properties of long-chain molecules and polymers are tailored to meet the demands of a specific application in a range of different ways. In the production of “smart” materials and other high-... Read More