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WS-CRDS: Precision Trace Gas Analysis and Simplified Stable Isotope Measurements
Friday, December 05, 2008
Eric R. Crosson
Wavelength-scanned cavity ring-down spectroscopy (WSCRDS) is fast gaining worldwide acceptance as a superior tool for trace gas analysis, because it combines operational simplicity and portability ...
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World Genome Data Analysis Summit 2012: Big Data, Big Problems, and Thoughtful Solutions
Wednesday, December 12, 2012
Robert L. Stevenson, Ph.D.
The World Genome Data Analysis Summit attracted about 70 scientists and engineers to the Monaco Hotel in San Francisco, CA, November 27–29 to talk shop on DNA data.
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Whole Genome Amplification: Extending Beyond the Limitations of Traditional PCR
Monday, April 04, 2005
Alicia Pruett
Tony Favello
Ernie Mueller
The history of molecular biology is marked by technological advances that have opened up the investigation of both fundamental and applied biological problems.
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When Analyzing Cancer at the Molecular Level, Microliters Matter
Friday, November 30, 2007
This year, more than 1.4 million Americans will be diagnosed with cancer. An extremely complex disease family, cancer affects all types of people, from all nationalities and genetic make-ups.
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What’s New in Optical Spectroscopy at Pittcon® 2013?
Friday, May 10, 2013
Mark Fisher
Soon after the first spectrophotometer was built, the challenge of improving it began. How could we make spectrophotometers better? Could we make them smaller, faster, or perhaps improve the ...
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What Should I Consider Before Buying an Automated Liquid Handler?
Wednesday, March 06, 2013
James Netterwald
Those in the market for an automated liquid handler have a number of considerations, as explained in this article. Types of dispensers for automated liquid handlers are peristaltic pumps, ...
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What Lab Managers Should Know About Managing and Reviewing Orphan Chromatographic Data in Light of the FDA’s Quality Metrics Initiative
Monday, July 09, 2018
Heather Longden
Pharmaceutical industry laboratory managers have likely been following the FDA’s Quality Metrics Initiative, which aims to prevent and mitigate drug shortages and encourage manufacturers to adopt ...
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What is “Hot” in Column Technologies for Liquid Chromatography?
Thursday, December 04, 2008
Frantisek Svec
It has been just over 100 years since Russian botanist Mikhail Semionovich Tswett invented the separation technique that he named chromatography.
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Validating Process and Action Limits for Automated Liquid Handlers in Volume-Dependent Assays
Wednesday, August 19, 2009
Keith Volk
Errors in automated liquid handling can have a significant impact on data integrity. Since automated liquid handling is a relatively new and rapidly advancing technology, standardized verification ...
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Utilizing Extended Linear Velocity to Maximize Peak Capacity in UHPLC
Tuesday, November 01, 2011
Dawn Stickle
Bob Giuffre
Historically, plate height as given by the Van Deemter equation has been used as the measure for separation efficiency in terms of contribution from the A, B, and C term versus linear velocity.
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USP <232> and <233> are Issued: Quo Vadis?
Thursday, May 31, 2018
Robert L. Stevenson, Ph.D.
This article explores whether to develop and support assays in-house or outsource them.
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Using MALS-UV-RI Detection for Accurate Characterization of PEGylated Proteins
Saturday, October 01, 2011
Michelle Chen
PEGylation involves covalent attachment of synthetic polyethylene glycol (PEG) chains to another molecule, usually a protein, peptide, or nucleotide.
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Using Light Scattering to Characterize SiO2 Chemical Mechanical Planarization Slurries
Sunday, February 01, 2009
Hui Ning
Chemical mechanical planarization (CMP) slurries are typically colloidal dispersions of silicon dioxide (SiO2) in an acid or base solution. They are integral to the semiconductor industry, emerging as...
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Using Inductively Coupled Plasma (ICP) Metal Data and Alkalinity Results for Effective Screening of Acidity Samples
Tuesday, May 15, 2012
Curtis Callahan
Acidity and alkalinity analyses are quantitatively and qualitatively related. These analyses are used in determining water quality, especially in areas of mining.
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Using FTIR Spectroscopy to Analyze Gemstones
Thursday, May 29, 2008
Stephen Lowry
Due to the increasing popularity and high prices of quality gemstones, there is a large market for less expensive stones that resemble the real thing.
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Using FAIMS to Increase Selectivity for LC-MS Analyses
Wednesday, June 01, 2005
Roger Guevremont
Beata Kolakowski
In the development of many LC-MS methods, interferences are commonplace. In an environment in which data must stand up to rigorous scrutiny, such as in the pharmaceutical industry, selectivity of ...
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Use of Radio Frequency Identification (RFID) for Sample Tracking
Tuesday, July 31, 2012
Hanan Davidowitz
Many solutions are available for sample tracking and identification.
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Use of qPCR to Detect Biomarkers for Assessing Stem Cells
Saturday, October 01, 2011
Jaime Sabel
In the human body, undifferentiated stem cells are the raw material used to repopulate tissues and organs in response to accidental cell death or normal cell turnover.
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Use of Microcoil Probes to Acquire More Sensitive NMR Spectral Data
Tuesday, February 01, 2005
Peter Froehlich
Nuclear magnetic resonance (NMR) spectroscopy is a powerful analytical technique that is commonly used to provide structural information as well as other chemical metrics such as sample composition ...
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Use of Integrated Data Analysis to Gain an Advantage in Biomarker Discovery and Personalized Medicine
Saturday, October 01, 2011
Jens Hoefkens
The genomic revolution of the last two decades has provided pharmaceutical companies with an almost overwhelming number of potential drug targets.
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