Technical Articles

The use of MS in the clinical laboratory really took off with liquid chromatography-tandem mass spectrometry. Its adoption over the last 15 years has been driven by the need for greater immunoassay ... read more

It’s important to realize that information gets filtered and distorted by the inherent behavior of a measurement process. read more

In the previous two columns (January/February and April 2016), we looked at the basic ideas behind control charts, saw how to construct the common X-bar and R charts and discovered that only two ... read more

In the previous column (January/February 2016), we looked at the basic ideas behind control charts and saw how to construct a common X-bar and R chart. read more

Light scattering is the most powerful tool for characterizing the size, shape, interactions and function of nanoparticles. read more

Thermal analysis by structural characterization (TASC) combines with differential scanning calorimetry (DSC) and light microscopy to provide a powerful technique for characterizing polymers, ... read more

The current standard of care for infectious disease management typically involves a nucleic acid amplification test (NAAT) to produce a definitive diagnosis. Due to the complexity of molecular ... read more

Before analytical results can be generated, a laboratory requires a suitable calibrated instrument, a trained analyst, an approved/validated method, appropriate reference materials, a standard ... read more

There are currently no promulgated U.S. EPA methods for the determination of total nitrogen in ambient water and wastewater. There are approved methods for the determination of inorganic nitrogen (NO3... read more

The cell-based assay arena is slowly entering center stage due to the major and growing medical problems facing the world—both financial (i.e., drug development) and curative (i.e., antibiotic ... read more