Read the Latest Technical Articles for Lab Professionals - Technical Articles

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A High-Throughput Device for Processing Samples on Solid Supports
Saturday, April 01, 2006
O. Mitch Griffith
Crime statistics now support the effectiveness of aggressively analyzing breaking-and-entering cases and developing genotype databases of these felons. read more
A Microfluidics-Based Droplet Plate Reader for Nucleic Acid and Protein Quantification
Wednesday, September 01, 2010
Tony Montoye
Life science laboratories are gradually moving toward automated liquid handling to achieve cost reduction, productivity increases, and improved data consistency and quality. read more
A Microwave Sample Preparation Procedure for the Commercial Testing Lab
Friday, February 15, 2013
Sumedh Phatak
Commercial testing laboratories that offer services for trace metals analysis have realized a variety of potential growth opportunities given the current passing of various local and international ... read more
A Molecular Diagnostic Platform for Use in the Physician’s Office to Treat Infectious Disease
Tuesday, April 28, 2015
Ihor Boszko Shana Kelley
The current standard of care for infectious disease management typically involves a nucleic acid amplification test (NAAT) to produce a definitive diagnosis. Due to the complexity of molecular ... read more
A New Paradigm for the Development of Fluorescent RNA Imaging Technology Using Synthetic Molecules
Monday, October 02, 2006
Kazunori Koide
In vivo protein imaging technology has been greatly advanced over the last decade by the development of green fluorescent protein (GFP) and its derivatives as investigational tools. read more
A Novel Chemical Route to Stable, Regenerable Zirconia-Based Chiral Stationary Phases for HPLC
Saturday, October 01, 2005
Richard A. Henry Clayton V. McNeff Bingwen Yan Thomas R. Hoye
High-performance liquid chromatography has become the dominant method for the analytical and preparative separation of chiral pharmaceuticals. read more
A Novel Mechanism for Controlling and Monitoring Real-Time Pipet Information in a Manual System
Thursday, September 13, 2007
Jim Petrek
The modern manual pipet has been a laboratory workhorse for several decades, providing researchers with a convenient tool to transfer liquids from one vessel to another with high levels of confidence ... read more
A Novel Performance Test for Outlet Check Valve Function in HPLC Pumps
Tuesday, September 28, 2010
Eduard Rogatsky Matthew Gallitto Daniel T. Stein
Check valves are a vital mechanical component of HPLC pump hardware. A detailed description of check valve function and hardware designs is given in Ref. 1. read more
A Practical Guide to Publishing RT-qPCR Data That Conform to the MIQE Guidelines
Tuesday, March 23, 2010
Sean Taylor
Real-time quantitative PCR (qPCR) has become a definitive technique for quantitating differences in gene expression levels between samples. read more
A Promise Kept: Stem Cells Key to Life-Saving Operation
Wednesday, August 26, 2009
John Meech
Prof. Anthony Hollander had always believed that he would be able to save lives. He believed it so strongly, in fact, that he wrote to a television program as a child asking for a few tools to help ... read more
A Single Molecular Multianalyte Fluorescent Probe and Its Application to Imaging Intracellular Multianalyte Dynamics
Tuesday, October 10, 2006
Hirokazu Komatsu Kotaro Oka Koji Suzuki
Single molecular multianalyte sensors are molecular sensors that can determine multiple analytes by recognition of the various analytes based on the difference of the spectral changes. read more
A System Approach to Automated Scanning Electron Microscopy
Tuesday, August 02, 2011
Timothy J. Drake Frederick H. Schamber
Much of the innovative activity in scanning electron microscopes (SEMs)has been devoted to ultrahigh-magnification instruments for the use of researchers characterizing materials and processes at ... read more
A Systematic Computational Approach for Identifying Small Molecules From Accurate-Mass Fragmentation Data
Saturday, November 03, 2007
Daniel L. Sweeney
The relative ease of obtaining accurate-mass fragmentation data on modern LC-MS instruments, faster computers, and the availability of large molecular structure databases have recently made it ... read more
A Thermal Analysis Technique That Combines Differential Scanning Calorimetry and Light Microscopy
Wednesday, June 24, 2015
Mike Reading Duncan Stacey
Thermal analysis by structural characterization (TASC) combines with differential scanning calorimetry (DSC) and light microscopy to provide a powerful technique for characterizing polymers, ... read more
A Valve Switching Ion Chromatography System With Integrated Automation Management
Friday, September 01, 2006
Richard Jack Rong Lin Brian De Borba Kannan Srinivasan Yoko Sekiguchi Yuichi Nakanishi Kazue Yoshimura
Valve switching applications are becoming popular in ion chromatography (IC). Example applications include matrix diversion or matrix elimination prior to analysis of trace components. read more
A Versatile Column for Surfactant Analysis by HPLC
Friday, November 25, 2005
Xiaodong Liu Chris Pohl
Surfactants are widely used for industrial, agricultural, and pharmaceutical applications, in products as diverse as pesticides, detergent powders, petroleum products, cosmetics,and pharmaceuticals. read more
A Weak Anion-Exchange/Reversed-Phase Mixed-Mode HPLC Column and its Applications
Monday, October 01, 2007
Xiaodong Liu Christopher Pohl
Mixed-mode columns address key challenges in analytical method development for HPLC. Reversed-phase (RP) columns (e.g., C18) are most widely used for HPLC separations. read more
A Weak Cation-Exchange, Reversed-Phase Mixed-Mode HPLC Column and its Applications
Friday, April 17, 2009
Xiaodong Liu Christopher Pohl
Basic compounds are widely used in many areas, such as pharmaceutical development, biological research, consumer products, and in the chemical industry. Although reversed-phase (RP) liquid ... read more
A Zoom Fluorescence Research Microscope for Macro- to Microfluorescence Imaging
Friday, November 25, 2005
Christopher Higgins
Scientists are increasingly interested in viewing both ends of the research spectrum—from cellular and subcellular level observations to tissue,organ, and whole animal studies. read more
Absolute Size Exclusion Chromatography
Monday, March 24, 2008
Ulf Nobbmann
Size exclusion chromatography (SEC) and dynamic light scattering (DLS) are common technologies in protein laboratories. read more

Technical Articles

Sort

A High-Throughput Device for Processing Samples on Solid Supports

A Microfluidics-Based Droplet Plate Reader for Nucleic Acid and Protein Quantification

A Microwave Sample Preparation Procedure for the Commercial Testing Lab

A Molecular Diagnostic Platform for Use in the Physician’s Office to Treat Infectious Disease

A New Paradigm for the Development of Fluorescent RNA Imaging Technology Using Synthetic Molecules

A Novel Chemical Route to Stable, Regenerable Zirconia-Based Chiral Stationary Phases for HPLC

A Novel Mechanism for Controlling and Monitoring Real-Time Pipet Information in a Manual System

A Novel Performance Test for Outlet Check Valve Function in HPLC Pumps

A Practical Guide to Publishing RT-qPCR Data That Conform to the MIQE Guidelines

A Promise Kept: Stem Cells Key to Life-Saving Operation

A Single Molecular Multianalyte Fluorescent Probe and Its Application to Imaging Intracellular Multianalyte Dynamics

A System Approach to Automated Scanning Electron Microscopy

A Systematic Computational Approach for Identifying Small Molecules From Accurate-Mass Fragmentation Data

A Thermal Analysis Technique That Combines Differential Scanning Calorimetry and Light Microscopy

A Valve Switching Ion Chromatography System With Integrated Automation Management

A Versatile Column for Surfactant Analysis by HPLC

A Weak Anion-Exchange/Reversed-Phase Mixed-Mode HPLC Column and its Applications

A Weak Cation-Exchange, Reversed-Phase Mixed-Mode HPLC Column and its Applications

A Zoom Fluorescence Research Microscope for Macro- to Microfluorescence Imaging

Absolute Size Exclusion Chromatography

Product Guide

Micromachined HPLC Columns Can Revolutionize Proteomics Workflows

Buyer's Guide: GC-MS for Monitoring Environmental Pollutants

Refocusing the Lens of Cancer Screening

Study: NGS Should Be Go-to Technology on Day Zero of the Next Pandemic

Overcoming Common Challenges in Sample Viability for Single-Cell Research