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Innovations in Gravimetric Preparation of Analytical Solutions: Regulatory and Compendial Perspectives
Tuesday, June 05, 2012
Gregory P. Martin
Advances in technology for the preparation of solutions have the potential to improve accuracy in the testing of pharmaceutical samples.
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Innovation Thrives at the American Society for Mass Spectrometry 2013
Tuesday, August 06, 2013
Paul O Danis
When J.J. Thomson, the father of mass spectrometry, published his seminal book, Rays of Positive Electricity, 100 years ago, he could not have imagined the vast array of applications that would be ...
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Use of Transgenic Mouse Models to Test for Carcinogenicity
Tuesday, April 21, 2015
Scott Hickman
Carcinogenicity studies are conducted to determine the tumorigenic potential of pharmaceuticals and chemicals, as required by regulatory authorities. Two-year bioassays in rats and mice have ...
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Infrared Thermal Cameras: Technology Overview and Buyers’ Guide
Wednesday, April 11, 2012
T. Keith Brock
Users in the market for infrared thermal cameras have a number of selection criteria prior to purchase. This article is a comprehensive guide to choosing an IR thermal camera. The author discusses ...
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Informatics for the Sciences at Molecular Med Tri-Con 2014: Show Me the Data!
Wednesday, March 26, 2014
Robert L. Stevenson, Ph.D.
Data management is the current choke point in many scientific endeavors. New workflows enabled by advances in hardware and software are making big data a reality for many labs and staff. To me, big ...
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Influence of Sample Preparation on the Assay of Phytochemicals
Wednesday, March 01, 2006
Devanand L. Luthria
Sample preparation is often considered a means to an end.
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Increasing the Stability of Liquid Stationary Phases for Improved Stability in High-Temperature GC
Wednesday, March 01, 2006
Jaap de Zeeuw
Coen Duvekot
Martine Barnes
The attempt to stabilize stationary phases for use in gas chromatography is ongoing.
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Improving Tools for Structured Query Language (SQL)
Monday, December 10, 2012
Robert L. Stevenson, Ph.D.
Since structured query language (SQL) was introduced 40 years ago, it has evolved and mutated to become the most popular tool for managing tabular databases.
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Improving the Laboratory Work Experience When Homogenizing
Friday, November 28, 2008
Karl Jahn
It is no secret to researchers who homogenize tissue samples as part of their regular laboratory routine that the job can be messy and loud, and produce results that are sometimes inconsistent.
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Improving Quantitative Accuracy and Precision of Isobaric Labeling Strategies for Quantitative Proteomics Using Multistage (MS3) Mass Spectrometry
Tuesday, January 15, 2013
Emanuel M. Schreiber
Over the past decade, the field of proteomics has progressed from the identification of proteins in biological samples to protein quantification. Several strategies have been developed, one of which ...
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Improving and Speeding up the Characterization of Substances, Materials, and Products: Benefits and Potentials of High-Speed DSC
Monday, April 10, 2006
Vincent B.F. Mathot
Geert Vanden Poel
Thijs F.J. Pijpers
High-speed calorimetry, and specifically high-speed differential scanning calorimetry (DSC), has received a great deal of attention in recent years.
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Improved Column Chromatography Performance Using Arginine
Thursday, February 01, 2007
Daisuke Ejima
Kouhei Tsumoto
Tsutomu Arakawa
Protein purification and analysis using column chromatography is facing new challenges because of increasing demands in the proteomic and biotechnology fields.
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Implementing Natural Ventilation in the Offices of a Research Laboratory Building
Tuesday, June 01, 2010
Chris Flint Chatto
The University of Washington (UW) is a leading public research and educational institution, with its largest of three campuses located in Seattle and adjacent to Lake Washington.
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Impact of HTS on Multidetection Microplate Readers and Benefits For Life Science Research Laboratories
Tuesday, August 01, 2006
Xavier Amouretti
The basic concept behind high-throughput screening (HTS) is a numbers game: If one has the technical ability to test thousands upon thousands of potential drug compounds against a specific target, it ...
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Identifying Pharmaceuticals in Surface Water Using LC-MS/MS in Both Positive and Negative Ion Modes
Thursday, January 01, 2009
Chin-Kai Meng
Compounds such as antibiotics, over-the- counter medicines, and caffeine drain through the sewage system largely unaltered into rivers and streams, and even enter the drinking water supply in very ...
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Identification of Volatile and Semivolatile Organic Compounds in Salt Lake Brine
Thursday, September 01, 2011
Qianqian Song
Bin Xu
Xinning Li
Wu Li
Guimin Qian
The deposited salts and brine from salt lakes are important industrial resources for many kinds of salts, such as edible salt, potassium, boron, lithium, and a few heavy metals.
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Hyphenation: The Next Step in Thermal Analysis
Friday, January 01, 2010
Kevin P. Menard
Richard Spragg
Greg Johnson
Craig Sellman
Thermal analysis, like most mature technologies, sees mostly incremental increases in its capabilities, such as the introduction of modulated temperature techniques in the early 1990s or the ...
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Hydrogen/Deuterium Exchange-MS for Biologics: Higher-Order Structure Analysis and Epitope Mapping
Monday, January 01, 2018
Yoshitomo Hamuro
Biologics are the fastest-growing sector in the pharmaceutical industry, with global sales approaching $200 billion and making up about 20% of all pharmaceuticals.
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HPLC Column Technology: The First 50 Years
Friday, September 28, 2018
Ronald E. Majors
This article focuses on the role of the column throughout the history of HPLC.
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HPLC 2013: 40th International Symposium on High Performance Liquid Phase Separations and Related Techniques
Monday, March 03, 2014
Robert L. Stevenson, Ph.D.
The prior 39 symposia in the HPLC series span 40 years and global locations in Asia, Europe, and North America, but this was the first in the Southern Hemisphere.
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