Super resolution imaging techniques have provided great advances in the observation of nanoscopic cell structures, however, a large gap still exists between lateral and axial resolution. This gap, in which axial resolution falls behind lateral resolution by a factor of two to three, limits the ability to view biological structures as they truly exist – in 3D. A research team led by Göttingen University, including the University of Würzburg and the Center for Cancer Research in the US, recently combined two imaging techniques, allowing them to achieve isotropic super resolution for imaging of biological samples.
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