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Title
The Science of a Lab Relocation
Thursday, June 20, 2019
George Rohlfing
Key points to ensure a successful lab relocation.
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Natural Product Drug Discovery From Marine Organisms With Advanced UPLC and MS Technology
Wednesday, May 22, 2019
Espen Hansen
A marine bioprospecting project demonstrated the use of MS/MS-based molecular networking as a dereplication strategy to identify known compounds, their analogs, and related compounds.
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How to Choose the Right Liquid Handling Automation Platform
Friday, January 11, 2019
Hal Wehrenberg
This article discusses some of the key points to consider when choosing a liquid handling platform for your laboratory.
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Automation in Bioprocess Development: Near-, Mid-, and Long-Term Opportunities
Tuesday, January 08, 2019
Paul Denny-Gouldson
Claire Hill
Automation, combined with other technological advances such as the Internet of Things (IoT) and analytics platforms like?machine?learning,?will be a major part of the future of bioprocess development.
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Top-Down Proteomics: An Emerging Technology Propelled by Mass Spectrometry
Wednesday, July 26, 2017
Rohan A. Thakur
Rapid developments in mass spectrometry technology facilitate innovative solutions to the challenges in top-down proteomics.
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Long-Range Genomics Is Reviving a Lost Art
Wednesday, July 26, 2017
Chris Boles
The instrument described here was designed to treat DNA gently enough that users can prepare libraries of extremely large fragments directly from blood samples, bacterial and tissue cultures, or other...
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Scalable Synthesis Technology
Wednesday, June 07, 2017
Philipp Wenter
A DNA synthesis platform addresses the need for smaller-scale oligo production without sacrificing quality, accuracy or turnaround time.
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A Redesigned Confocal Microscope for Super-Resolution Microscopy
Tuesday, May 09, 2017
Erik Manders
Peter Drent
Ronald Breedijk
A simple optical redesign converts a standard confocal microscope to a super-resolution microscope.
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Liquid Handling Uses Acoustic Droplet Ejection for Improved Results
Monday, May 08, 2017
Mark Fischer-Colbrie
Acoustic drop ejection systems can pave the way for entirely new applications, bringing higher throughput and greater flexibility to many areas of biology.
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Individual Cell Analysis for Protein Expression and Cell Health Markers
Tuesday, March 21, 2017
Robin T. Clark
The Muse instrument uses microcapillary fluidics and preoptimized reagents to create an inexpensive, compact, portable cell analyzer that requires minimal setup and no expertise to operate.
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Comparison of ICP-QQQ and MP-AES to Alternative Atomic Spectroscopy Techniques
Friday, February 17, 2017
Shane Elliott
This article gives an overview of the various atomic spectroscopy techniques available to address a range of applications in environmental science, food and agriculture, life sciences and academic ...
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Refrigeration Practices for Biological Sample Preservation
Friday, February 17, 2017
Robert Sandor
Preservation of biological samples such as tissues, plasma and forensic and pathology specimens relies on maintaining proper storage temperatures and on the type of sample and analysis to be done. ...
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Super-Resolution Microscopy Techniques Combine to Clarify Spatiotemporal Structure of the Endoplasmic Reticulum
Friday, February 17, 2017
Robert L. Stevenson, Ph.D.
Super-resolution microscopy encompasses several new techniques for direct spatiotemporal imaging of structural features much smaller than the diffraction limit of light. The endoplasmic reticulum (ER)...
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siRNA Knockdown: Implementing Negative Controls in Antibody QC
Friday, January 20, 2017
Will Olds
This article presents an overview of short interfering RNA (siRNA) knockdown, a powerful negative control method, followed by tips to optimize siRNA transfection experiments.
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NGS Library Validation Using Automated Capillary Gel Electrophoresis
Friday, November 11, 2016
Varouj Amirkhanian
Eric Tsai
Jemmie Chang
Alice Lin
Next-generation sequencing (NGS) is widely used in genomics, epigenetics and transcriptomics, etc., and also in such clinical diagnostics applications as cancer screening and drug development.
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For Accurate Cell-Based Assay Results, Transfer Technique Matters
Wednesday, November 09, 2016
John Lesnick
From smaller-scale assays to industrial-scale screening operations, cell-based assays are critical for applications that include elucidating basic mechanisms of cell function, target validation and ...
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Ten Tips for Proper Pipetting
Monday, November 07, 2016
A. Björn Carle
Pipetting proficiency is one of the most critical elements to ensure accuracy and precision, particularly in the face of high personnel turnover, growing laboratory workloads and increasingly complex ...
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Achieving Accuracy and Reproducibility With Electronic Pipettes
Monday, November 07, 2016
Nora Meneceur
Beatrice Guieu-Presle
Researchers are continuously seeking ways to improve efficiency while ensuring that their methods are reliable and their research is reproducible.
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Automating 3-D Cell Culture and Screening by Flow Cytometry and High-Content Imaging
Friday, November 04, 2016
Michael Kowalski
For over half a century, researchers have used 2-D cell culture methods, though the physiological relevance of these models has frequently been in doubt, largely because monolayer culture systems ...
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High-Throughput Drug Screening of Multicellular Tumor Spheroids
Tuesday, September 27, 2016
Ana Maria P. Pardo
Hannah J. Gitschier
David H. Randle
Terry Riss
Three-dimensional (3-D) culture models are increasingly being used for drug discovery in oncology, as they better represent the complexity of the in vivo microenvironment of solid tumors.
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